A Combined LC-MS and Immunoassay Approach to Characterize Preservative-Induced Destabilization of Human Papillomavirus Virus-like Particles Adsorbed to an Aluminum-Salt Adjuvant.

Autor: Caringal RT; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA., Hickey JM; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA., Sharma N; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA., Jerajani K; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA., Bewaji O; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA., Brendle S; Department of Pathology, College of Medicine, Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA., Christensen N; Department of Pathology, College of Medicine, Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA., Batwal S; Serum Institute of India Pvt. Ltd., Pune 411028, India., Mahedvi M; Serum Institute of India Pvt. Ltd., Pune 411028, India., Rao H; Serum Institute of India Pvt. Ltd., Pune 411028, India., Dogar V; Serum Institute of India Pvt. Ltd., Pune 411028, India., Chandrasekharan R; Serum Institute of India Pvt. Ltd., Pune 411028, India., Shaligram U; Serum Institute of India Pvt. Ltd., Pune 411028, India., Joshi SB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA., Volkin DB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2024 May 26; Vol. 12 (6). Date of Electronic Publication: 2024 May 26.

Formulation development and comparability studies with an aluminum-salt adjuvanted SARS-CoV-2 spike ferritin nanoparticle vaccine antigen produced from two different cell lines.

Autor: Kumru OS; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS 66047, USA., Sanyal M; Department of Biochemistry, Stanford University School of Medicine, Palo Alto, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA., Friedland N; Department of Biochemistry, Stanford University School of Medicine, Palo Alto, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA., Hickey JM; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS 66047, USA., Joshi R; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS 66047, USA., Weidenbacher P; Department of Biochemistry, Stanford University School of Medicine, Palo Alto, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA., Do J; Department of Biochemistry, Stanford University School of Medicine, Palo Alto, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA., Cheng YC; Department of Biochemistry, Stanford University School of Medicine, Palo Alto, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA., Kim PS; Department of Biochemistry, Stanford University School of Medicine, Palo Alto, CA 94305, USA; Sarafan ChEM-H, Stanford University, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Joshi SB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS 66047, USA., Volkin DB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS 66047, USA. Electronic address: volkin@ku.edu.

Publikováno v: Vaccine [Vaccine] 2023 Oct 20; Vol. 41 (44), pp. 6502-6513. Date of Electronic Publication: 2023 Aug 22.

Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor-binding domain (RBD).

Autor: Kumru OS; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USA., Bajoria S; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USA., Kaur K; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USA., Hickey JM; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USA., Van Slyke G; Division of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Doering J; Division of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Berman K; Division of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Richardson C; Technical Operations, Icosavax, Seattle, WA, USA., Lien H; Quality, Icosavax, Seattle, WA, USA., Kleanthous H; Discovery & Translational Sciences, Global Health, Bill and Melinda Gates Foundation, Seattle, WA, USA., Mantis NJ; Division of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, NY, USA., Joshi SB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USA., Volkin DB; Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USA.

Publikováno v: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2023 Aug; Vol. 19 (2), pp. 2264594. Date of Electronic Publication: 2023 Nov 06.

A genome-wide association study for loin depth and muscle pH in pigs from intensely selected purebred lines.

Autor: Desire S; The Roslin Institute, The University of Edinburgh, Midlothian, UK. sdesire@ed.ac.uk., Johnsson M; Swedish University of Agricultural Sciences, Uppsala, Sweden., Ros-Freixedes R; Departament de Ciència Animal, Universitat de Lleida-Agrotecnio-CERCA Center, Lleida, Spain., Chen CY; The Pig Improvement Company, Genus Plc, Hendersonville, TN, USA., Holl JW; The Pig Improvement Company, Genus Plc, Hendersonville, TN, USA., Herring WO; The Pig Improvement Company, Genus Plc, Hendersonville, TN, USA., Gorjanc G; The Roslin Institute, The University of Edinburgh, Midlothian, UK., Mellanby RJ; The Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Midlothian, UK., Hickey JM; The Roslin Institute, The University of Edinburgh, Midlothian, UK., Jungnickel MK; The Roslin Institute, The University of Edinburgh, Midlothian, UK.

Publikováno v: Genetics, selection, evolution : GSE [Genet Sel Evol] 2023 Jun 15; Vol. 55 (1), pp. 42. Date of Electronic Publication: 2023 Jun 15.

Multi-line ssGBLUP evaluation using preselected markers from whole-genome sequence data in pigs.

Autor: Jang S; Department of Animal and Dairy Science, University of Georgia, Athens, GA, United States., Ros-Freixedes R; Departament de Ciència Animal, Universitat de Lleida-Agrotecnio-CERCA Center, Lleida, Spain., Hickey JM; The Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Edinburgh, Scotland, United Kingdom., Chen CY; The Pig Improvement Company, Genus plc, Hendersonville, TN, United States., Herring WO; The Pig Improvement Company, Genus plc, Hendersonville, TN, United States., Holl J; The Pig Improvement Company, Genus plc, Hendersonville, TN, United States., Misztal I; Department of Animal and Dairy Science, University of Georgia, Athens, GA, United States., Lourenco D; Department of Animal and Dairy Science, University of Georgia, Athens, GA, United States.

Publikováno v: Frontiers in genetics [Front Genet] 2023 May 12; Vol. 14, pp. 1163626. Date of Electronic Publication: 2023 May 12 (Print Publication: 2023).