Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Hichem Ben Jannet"'
Publikováno v:
Molecules, Vol 29, Iss 13, p 3091 (2024)
Oleanolic acid (OA) is a vegetable chemical that is present naturally in a number of edible and medicinal botanicals. It has been extensively studied by medicinal chemists and scientific researchers due to its biological activity against a wide range
Externí odkaz:
https://doaj.org/article/0606db62c4a841aca85fdf952aa962cb
Autor:
Wiem Baccari, Ilyes Saidi, Insaf Filali, Mansour Znati, Moncef Tounsi, Roberta Ascrizzi, Guido Flamini, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 9, Pp 105044- (2023)
Oxidative stress is closely related to cancer aspects, such as the induction of gene mutations resulting from cellular injury and the effects on transcription and signal transduction factors. In addition, antibiotic resistance is also linked with oxi
Externí odkaz:
https://doaj.org/article/354930b596bb48f99250a061d0277e14
Autor:
Assia Hamdi, Mabrouk Horchani, Hichem Ben Jannet, Mejdi Snoussi, Emira Noumi, Nouha Bouali, Adel Kadri, Flavio Polito, Vincenzo De Feo, Hayet Edziri
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1669 (2023)
Citrus, which belongs to the Rutaceae family, is a very widespread genus in the Mediterranean Basin. In Tunisia, various parts of these spontaneous or cultivated plants are used in common dishes or in traditional medicine. The purpose of this work wa
Externí odkaz:
https://doaj.org/article/2881c46052fb455eb0c2029817da2809
Autor:
Mayssa Zayene, Faisal K. Algethami, Hani Nasser Abdelhamid, Mohamed R. Elamin, Babiker Y. Abdulkhair, Youssef O. Al-Ghamdi, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 11, Pp 104177- (2022)
Despite all the progress made to enrich the existing bank of drugs used to treat and cure Alzheimer and cancer patients, there is still a need to research and develop new bioactive candidates with superior efficacy but minimal side effects. In this c
Externí odkaz:
https://doaj.org/article/87344b2cfcd24c4c9873581e81d2afa2
Autor:
Ghofrane Lahmadi, Mabrouk Horchani, Amal Dbeibia, Abdelkarim Mahdhi, Anis Romdhane, Ata Martin Lawson, Adam Daïch, Abdel Halim Harrath, Hichem Ben Jannet, Mohamed Othman
Publikováno v:
Molecules, Vol 28, Iss 12, p 4655 (2023)
As part of the valorization of agricultural waste into bioactive compounds, a series of structurally novel oleanolic acid ((3β-hydroxyolean-12-en-28-oic acid, OA-1)-phtalimidines (isoindolinones) conjugates 18a–u bearing 1,2,3-triazole moieties we
Externí odkaz:
https://doaj.org/article/f255bfd412ca4455837e6e59ad9d82ae
Autor:
Ameur Rahmouni, Anis Romdhane, Abderrahim Ben said, Vincent Guérineau, David Touboul, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 1974-1982 (2019)
3,6-Dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 3 was prepared by an intramolecular cyclization of N-(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl) acetamide 2 in ethanol in the presence of piperidine. N-allylation and N-propargyl alkylation
Externí odkaz:
https://doaj.org/article/db3c44c67d0442469b6b73527d66e038
Autor:
Karim Chouaïb, Anis Romdhane, Stéphanie Delemasure, Patrick Dutartre, Nicolas Elie, David Touboul, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3732-3742 (2019)
The oleanolic acid (1), a natural pentacyclic triterpenoid, was quantitatively isolated from pomace olive (Olea europaea L.) under ultra-sonication conditions (6.8 g (3.4 mg/g DW)). Two series of oleanolic acid-1-phenyl-1H-[1,2,3]triazol-4-ylmethyles
Externí odkaz:
https://doaj.org/article/c77d83f9e3f742eda325d0aeda342f60
Autor:
Ikram Allagui, Mabrouk Horchani, Nourhene Zammel, Maroua Jalouli, Abdelfatteh Elfeki, Choumous Kallel, Lamjed Mansour, Salah Alwasel, Abdel Halim Harrath, Hichem Ben Jannet, Mohamed Salah Allagui, Kheiria Hcini
Publikováno v:
Molecules, Vol 28, Iss 1, p 26 (2022)
In recent decades, the use of herbs and plants has been of great interest, as they have been the sources of natural products, commonly named as bioactive compounds. In specific, the natural compounds from the Capparaceae family which has been proved
Externí odkaz:
https://doaj.org/article/d578c35941a94ca28c7f408a1a278f88
Autor:
Zaineb Abdelkafi-Koubaa, Imen Aissa, Hichem Ben Jannet, Najet Srairi-Abid, Naziha Marrakchi, Samia Menif
Publikováno v:
Molecules, Vol 27, Iss 16, p 5086 (2022)
In the present study, we assess tyrosol derivatives bearing 3,5-disubstituted isoxazoles and 1,4-disubstituted triazoles for their ability to inhibit the proliferation of K562 cells derived from leukemia as well as primary chronic myeloid leukemia (C
Externí odkaz:
https://doaj.org/article/347e41a799e44221a0412bc3d2c9b529
Autor:
Mabrouk Horchani, Niels V. Heise, René Csuk, Hichem Ben Jannet, Abdel Halim Harrath, Anis Romdhane
Publikováno v:
Molecules, Vol 27, Iss 16, p 5303 (2022)
In addition to vaccines, antiviral drugs are essential in order to suppress COVID-19. Although some inhibitor candidates have been determined to target the SARS-CoV-2 protein, there is still an urgent need to continue researching novel inhibitors of
Externí odkaz:
https://doaj.org/article/4c42a2fbf83b4a4bbcfbea64f4139332