Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hicham Naimy"'
Autor:
Christian J. Hendriksz MD, Joseph Muenzer MD, PhD, Barbara K. Burton MD, Luying Pan PhD, Nan Wang MS, Hicham Naimy PhD, Arian Pano MD, MPH, Ann J. Barbier MD, PhD
Publikováno v:
Journal of Inborn Errors of Metabolism and Screening, Vol 3 (2015)
Hunter syndrome (mucopolysaccharidosis II [MPS II]) is characterized by lysosomal glycosaminoglycan (GAG) accumulation. Although a majority of patients with MPS II experience neurocognitive involvement, few data are available on cerebrospinal fluid (
Externí odkaz:
https://doaj.org/article/44f864c277834cba9dd735f119dfda5b
Autor:
Hicham Naimy, Barbara K. Burton, Nan Wang, Luying Pan, Arian Pano, Ann J. Barbier, Christian J. Hendriksz, Joseph Muenzer
Publikováno v:
Journal of Inborn Errors of Metabolism and Screening, Volume: 3, Article number: e150002, Published: 19 JUN 2019
Journal of Inborn Errors of Metabolism and Screening, Vol 3 (2015)
Journal of Inborn Errors of Metabolism and Screening v.3 2015
Journal of Inborn Errors of Metabolism and Screening
Instituto Genética para Todos (IGPT)
instacron:IGPT
Journal of Inborn Errors of Metabolism and Screening, Vol 3 (2015)
Journal of Inborn Errors of Metabolism and Screening v.3 2015
Journal of Inborn Errors of Metabolism and Screening
Instituto Genética para Todos (IGPT)
instacron:IGPT
Hunter syndrome (mucopolysaccharidosis II [MPS II]) is characterized by lysosomal glycosaminoglycan (GAG) accumulation. Although a majority of patients with MPS II experience neurocognitive involvement, few data are available on cerebrospinal fluid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c4674d9cb4b6a7c5966e73a2069bbd
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942015000100601&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2326-45942015000100601&lng=en&tlng=en
Autor:
Yongchang Qiu, Thomas McCauley, John R Moriarity, Kendall D. Powell, Patrick A. J. Haslett, Hicham Naimy, Ann J. Barbier, Jiang Wu
Publikováno v:
Bioanalysis. 8(4)
Aims: Heparan sulfate (HS) accumulates in the central nervous system in mucopolysaccharidosis III type A (MPS IIIA). A validated LC–MS/MS assay was developed to measure HS in human cerebrospinal fluid (CSF). Methods & results: HS was extracted and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f187c38a1cb5bec4bbdf46560fb697df
https://pubmed.ncbi.nlm.nih.gov/26847798
https://pubmed.ncbi.nlm.nih.gov/26847798
Publikováno v:
Journal of the American Society for Mass Spectrometry. 23:1498-1511
Heparan sulfate (HS) is a polysaccharide modified with sulfation, acetylation, and epimerization that enable its binding with protein ligands and regulation of important biological processes. Tandem mass spectrometry has been employed to sequence lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090e7ad01ca66915775ba657fc52a9a5
https://doi.org/10.1007/s13361-012-0429-4
https://doi.org/10.1007/s13361-012-0429-4
Autor:
Joseph Zaia, Xiaofeng Shi, Catherine E. Costello, Alicia M. Hitchcock, Christine A. Miller, Nancy Leymarie, Gregory O. Staples, Hicham Naimy, James M. Lau, Michael J. Bowman
Publikováno v:
PROTEOMICS. 9:686-695
A key challenge to investigations into the functional roles of glycosaminoglycans (GAGs) in biological systems is the difficulty in achieving sensitive, stable and reproducible mass spectrometric analysis. GAGs are linear carbohydrates with domains t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dec1b141216fea14ce8e035512cbb97
https://doi.org/10.1002/pmic.200701008
https://doi.org/10.1002/pmic.200701008
Publikováno v:
Biochemistry. 47:3155-3161
Heparan sulfate (HS) is a sulfated glycosaminoglycan attached to a core protein on the cell surface. Protein binding to cell surface HS is a key regulatory event for many cellular processes such as blood coagulation, cell proliferation, and migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af950ae33ba12658e9190008a5e7a07c
https://doi.org/10.1021/bi702043e
https://doi.org/10.1021/bi702043e
The biological functions of glycoconjugate glycans arise in the context of structural heterogeneity resulting from non-template driven biosynthetic reactions. Such heterogeneity is particularly apparent for the glycosaminoglycan (GAG) classes, of whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64992af6556bba90c9e6054361fffae8
https://europepmc.org/articles/PMC3329220/
https://europepmc.org/articles/PMC3329220/
Publikováno v:
Biochemistry. 49(17)
Heparan sulfate (HS) is a sulfated glycosaminoglycan located on the surface and extracellular matrix of mammalian cells. HS is constituted of highly N-sulfated domains (NS domains) interrupted by lower sulfation domains. The arrangement of these doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d08dad68825fb9066854fce465ed6a
https://pubmed.ncbi.nlm.nih.gov/20345121
https://pubmed.ncbi.nlm.nih.gov/20345121
Autor:
Kevin Kileen, Joseph Zaia, Karsten Kraiczek, Hicham Naimy, Gregory O. Staples, Hongfeng Yin, Catherine E. Costello
Publikováno v:
Analytical chemistry. 82(2)
Heparan sulfate (HS) and heparin are linear, heterogeneous carbohydrates of the glycosaminoglycan (GAG) family that are modified by N-acetylation, N-sulfation, O-sulfation, and uronic acid epimerization. HS interacts with growth factors in the extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481c2121dfe9ff4bb11eaef71512f71c
https://pubmed.ncbi.nlm.nih.gov/20000724
https://pubmed.ncbi.nlm.nih.gov/20000724