Mass composition of ultra-high energy cosmic rays from distribution of their arrival directions with the Telescope Array

Autor: Telescope Array Collaboration, Abbasi, R. U., Abe, Y., Abu-Zayyad, T., Allen, M., Arai, Y., Arimura, R., Barcikowski, E., Belz, J. W., Bergman, D. R., Blake, S. A., Buckland, I., Cheon, B. G., Chikawa, M., Fujii, T., Fujisue, K., Fujita, K., Fujiwara, R., Fukushima, M., Furlich, G., Globus, N., Gonzalez, R., Hanlon, W., Hayashida, N., He, H., Hibi, R., Hibino, K., Higuchi, R., Honda, K., Ikeda, D., Inoue, N., Ishii, T., Ito, H., Ivanov, D., Iwasaki, A., Jeong, H. M., Jeong, S., Jui, C. C. H., Kadota, K., Kakimoto, F., Kalashev, O., Kasahara, K., Kasami, S., Kawakami, S., Kawata, K., Kharuk, I., Kido, E., Kim, H. B., Kim, J. H., Kim, S. W., Kimura, Y., Komae, I., Kuzmin, V., Kuznetsov, M., Kwon, Y. J., Lee, K. H., Lubsandorzhiev, B., Lundquist, J. P., Matsumiya, H., Matsuyama, T., Matthews, J. N., Mayta, R., Mizuno, K., Murakami, M., Myers, I., Nagataki, S., Nakai, K., Nakamura, T., Nishio, E., Nonaka, T., Oda, H., Ogio, S., Onishi, M., Ohoka, H., Okazaki, N., Oku, Y., Okuda, T., Omura, Y., Ono, M., Oshima, A., Oshima, H., Ozawa, S., Park, I. H., Park, K. Y., Potts, M., Pshirkov, M. S., Remington, J., Rodriguez, D. C., Rott, C., Rubtsov, G. I., Ryu, D., Sagawa, H., Saito, R., Sakaki, N., Sako, T., Sakurai, N., Sato, D., Sato, K., Sato, S., Sekino, K., Shah, P. D., Shibata, N., Shibata, T., Shikita, J., Shimodaira, H., Shin, B. K., Shin, H. S., Shinto, D., Smith, J. D., Sokolsky, P., Stokes, B. T., Stroman, T. A., Takagi, Y., Takahashi, K., Takamura, M., Takeda, M., Takeishi, R., Taketa, A., Takita, M., Tameda, Y., Tanaka, K., Tanaka, M., Tanoue, Y., Thomas, S. B., Thomson, G. B., Tinyakov, P., Tkachev, I., Tokuno, H., Tomida, T., Troitsky, S., Tsuda, R., Tsunesada, Y., Udo, S., Urban, F., Warren, D., Wong, T., Yamazaki, K., Yashiro, K., Yoshida, F., Zhezher, Y., Zundel, Z.

We use a new method to estimate the injected mass composition of ultrahigh cosmic rays (UHECRs) at energies higher than 10 EeV. The method is based on comparison of the energy-dependent distribution of cosmic ray arrival directions as measured by the

Externí odkaz: http://arxiv.org/abs/2406.19286

Isotropy of Cosmic Rays beyond 10^{20}  eV Favors Their Heavy Mass Composition.

Autor: Abbasi RU; Department of Physics, Loyola University Chicago, Chicago, Illinois 60660, USA., Abe Y; Academic Assembly School of Science and Technology Institute of Engineering, Shinshu University, Nagano, Nagano 380-8554, Japan., Abu-Zayyad T; Department of Physics, Loyola University Chicago, Chicago, Illinois 60660, USA.; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Allen M; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Arai Y; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Arimura R; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Barcikowski E; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Belz JW; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Bergman DR; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Blake SA; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Buckland I; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Cheon BG; Department of Physics and The Research Institute of Natural Science, Hanyang University, Seongdong-gu, Seoul 426-791, Korea., Chikawa M; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Fujii T; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan.; Nambu Yoichiro Institute of Theoretical and Experimental Physics, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Fujisue K; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan.; Institute of Physics, Academia Sinica, Taipei City 115201, Taiwan., Fujita K; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Fujiwara R; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Fukushima M; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Furlich G; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Globus N; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Gonzalez R; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Hanlon W; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Hayashida N; Faculty of Engineering, Kanagawa University, Yokohama, Kanagawa 221-8686, Japan., He H; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Hibi R; Academic Assembly School of Science and Technology Institute of Engineering, Shinshu University, Nagano, Nagano 380-8554, Japan., Hibino K; Faculty of Engineering, Kanagawa University, Yokohama, Kanagawa 221-8686, Japan., Higuchi R; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Honda K; Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Kofu, Yamanashi 400-8511, Japan., Ikeda D; Faculty of Engineering, Kanagawa University, Yokohama, Kanagawa 221-8686, Japan., Inoue N; The Graduate School of Science and Engineering, Saitama University, Saitama, Saitama 338-8570, Japan., Ishii T; Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Kofu, Yamanashi 400-8511, Japan., Ito H; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Ivanov D; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Iwasaki A; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Jeong HM; Department of Physics, SungKyunKwan University, Jang-an-gu, Suwon 16419, Korea., Jeong S; Department of Physics, SungKyunKwan University, Jang-an-gu, Suwon 16419, Korea., Jui CCH; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Kadota K; Department of Physics, Tokyo City University, Setagaya-ku, Tokyo 158-8557, Japan., Kakimoto F; Faculty of Engineering, Kanagawa University, Yokohama, Kanagawa 221-8686, Japan., Kalashev O; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Kasahara K; Faculty of Systems Engineering and Science, Shibaura Institute of Technology, Minato-ku, Tokyo 337-8570, Japan., Kasami S; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Kawakami S; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Kawata K; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Kharuk I; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Kido E; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Kim HB; Department of Physics and The Research Institute of Natural Science, Hanyang University, Seongdong-gu, Seoul 426-791, Korea., Kim JH; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Kim JH; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Kim SW; Department of Physics, SungKyunKwan University, Jang-an-gu, Suwon 16419, Korea., Kimura Y; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Komae I; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Kuzmin V; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Kuznetsov M; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia.; Service de Physique Théorique, Université Libre de Bruxelles, Brussels 1050, Belgium., Kwon YJ; Department of Physics, Yonsei University, Seodaemun-gu, Seoul 120-749, Korea., Lee KH; Department of Physics, SungKyunKwan University, Jang-an-gu, Suwon 16419, Korea., Lubsandorzhiev B; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Lundquist JP; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA.; Center for Astrophysics and Cosmology, University of Nova Gorica, Nova Gorica 5297, Slovenia., Matsumiya H; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Matsuyama T; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Matthews JN; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Mayta R; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Mizuno K; Academic Assembly School of Science and Technology Institute of Engineering, Shinshu University, Nagano, Nagano 380-8554, Japan., Murakami M; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Myers I; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Lee KH; Department of Physics and The Research Institute of Natural Science, Hanyang University, Seongdong-gu, Seoul 426-791, Korea., Nagataki S; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Nakai K; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Nakamura T; Faculty of Science, Kochi University, Kochi, Kochi 780-8520, Japan., Nishio E; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Nonaka T; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Oda H; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Ogio S; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Onishi M; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Ohoka H; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Okazaki N; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Oku Y; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Okuda T; Department of Physical Sciences, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan., Omura Y; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Ono M; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Oshima A; College of Engineering, Chubu University, Kasugai, Aichi 487-8501, Japan., Oshima H; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Ozawa S; Quantum ICT Advanced Development Center, National Institute for Information and Communications Technology, Koganei, Tokyo 184-8795, Japan., Park IH; Department of Physics, SungKyunKwan University, Jang-an-gu, Suwon 16419, Korea., Park KY; Department of Physics and The Research Institute of Natural Science, Hanyang University, Seongdong-gu, Seoul 426-791, Korea., Potts M; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Pshirkov MS; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia.; Sternberg Astronomical Institute, Moscow M.V. Lomonosov State University, Moscow 119991, Russia., Remington J; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Rodriguez DC; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Rott C; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA.; Department of Physics, SungKyunKwan University, Jang-an-gu, Suwon 16419, Korea., Rubtsov GI; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Ryu D; Department of Physics, School of Natural Sciences, Ulsan National Institute of Science and Technology, UNIST-gil, Ulsan 689-798, Korea., Sagawa H; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Saito R; Academic Assembly School of Science and Technology Institute of Engineering, Shinshu University, Nagano, Nagano 380-8554, Japan., Sakaki N; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Sako T; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Sakurai N; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Sato D; Academic Assembly School of Science and Technology Institute of Engineering, Shinshu University, Nagano, Nagano 380-8554, Japan., Sato K; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Sato S; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Sekino K; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Shah PD; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Shibata N; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Shibata T; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Shikita J; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Shimodaira H; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Shin BK; Department of Physics, School of Natural Sciences, Ulsan National Institute of Science and Technology, UNIST-gil, Ulsan 689-798, Korea., Shin HS; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan.; Nambu Yoichiro Institute of Theoretical and Experimental Physics, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Shinto D; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Smith JD; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Sokolsky P; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Stokes BT; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Stroman TA; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Takagi Y; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Takahashi K; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Takamura M; Department of Physics, Tokyo University of Science, Noda, Chiba 162-8601, Japan., Takeda M; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Takeishi R; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Taketa A; Earthquake Research Institute, University of Tokyo, Bunkyo-ku, Tokyo 277-8582, Japan., Takita M; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan., Tameda Y; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Tanaka K; Graduate School of Information Sciences, Hiroshima City University, Hiroshima, Hiroshima 731-3194, Japan., Tanaka M; Institute of Particle and Nuclear Studies, KEK, Tsukuba, Ibaraki 305-0801, Japan., Tanoue Y; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Thomas SB; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Thomson GB; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Tinyakov P; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia.; Service de Physique Théorique, Université Libre de Bruxelles, Brussels 1050, Belgium., Tkachev I; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Tokuno H; Graduate School of Science and Engineering, Tokyo Institute of Technology, Meguro, Tokyo 152-8550, Japan., Tomida T; Academic Assembly School of Science and Technology Institute of Engineering, Shinshu University, Nagano, Nagano 380-8554, Japan., Troitsky S; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Tsuda R; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Tsunesada Y; Graduate School of Science, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan.; Nambu Yoichiro Institute of Theoretical and Experimental Physics, Osaka Metropolitan University, Sugimoto, Sumiyoshi, Osaka 558-8585, Japan., Udo S; Faculty of Engineering, Kanagawa University, Yokohama, Kanagawa 221-8686, Japan., Urban F; CEICO, Institute of Physics, Czech Academy of Sciences, Prague 182 21, Czech Republic., Warren D; Astrophysical Big Bang Laboratory, RIKEN, Wako, Saitama 351-0198, Japan., Wong T; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA., Yamazaki K; College of Engineering, Chubu University, Kasugai, Aichi 487-8501, Japan., Yashiro K; Department of Physics, Tokyo University of Science, Noda, Chiba 162-8601, Japan., Yoshida F; Graduate School of Engineering, Osaka Electro-Communication University, Hatsu-cho, Neyagawa-shi, Osaka 572-8530, Japan., Zhezher Y; Institute for Cosmic Ray Research, University of Tokyo, Kashiwa, Chiba 277-8582, Japan.; Institute for Nuclear Research of the Russian Academy of Sciences, Moscow 117312, Russia., Zundel Z; High Energy Astrophysics Institute and Department of Physics and Astronomy, University of Utah, Salt Lake City, Utah 84112-0830, USA.

Publikováno v: Physical review letters [Phys Rev Lett] 2024 Jul 26; Vol. 133 (4), pp. 041001.

Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation.

Autor: Echizen H; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Hanaoka K; Graduate School of Pharmaceutical Sciences, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, 105-8512, Japan. khanaoka@keio.jp., Shimamoto K; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Hibi R; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Toma-Fukai S; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.; Graduate School of Science and Technology, Nara Institute of Science and Technology, Nara, 630-0192, Japan., Ohno H; Graduate School of Pharmaceutical Sciences, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, 105-8512, Japan., Sasaki E; Graduate School of Pharmaceutical Sciences, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo, 105-8512, Japan., Komatsu T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Ueno T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Tsuchiya Y; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Machida-shi 194-8543, Tokyo, Japan., Watanabe Y; Faculty of Pharmaceutical Sciences, Showa Pharmaceutical University, Machida-shi 194-8543, Tokyo, Japan., Otsuka T; Graduate School of Medicine, Kyoto University, 53 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan., Saito H; Faculty of Pharmaceutical Sciences, Hokuriku University, 3 Ho Kanakawa-cho, Kanazawa, Ishikawa, 920-1181, Japan., Nagatoishi S; Medical Device Development and Regulation Research Center, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.; Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan., Tsumoto K; Medical Device Development and Regulation Research Center, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.; Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan., Kojima H; Drug Discovery Initiative, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Okabe T; Drug Discovery Initiative, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Shimizu T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Urano Y; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. uranokun@m.u-tokyo.ac.jp.; Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. uranokun@m.u-tokyo.ac.jp.

Publikováno v: Scientific reports [Sci Rep] 2023 Sep 30; Vol. 13 (1), pp. 16456. Date of Electronic Publication: 2023 Sep 30.

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Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.

Autor: Toma-Fukai S; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan., Hibi R; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan., Naganuma T; Department of Molecular Metabolic Regulation, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Shinjyuku-ku, Tokyo, Japan., Sakai M; Department of Molecular Metabolic Regulation, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Shinjyuku-ku, Tokyo, Japan., Saijo S; Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki, Japan., Shimizu N; Photon Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki, Japan., Matsumoto M; Department of Molecular Metabolic Regulation, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Shinjyuku-ku, Tokyo, Japan., Shimizu T; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. Electronic address: shimizu@mol.f.u-tokyo.ac.jp.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2020 Oct 23; Vol. 295 (43), pp. 14630-14639. Date of Electronic Publication: 2020 Aug 19.