Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hianara A Bustamante"'
Autor:
Hianara A Bustamante, Karina Cereceda, Alexis E González, Guillermo E Valenzuela, Yorka Cheuquemilla, Sergio Hernández, Eloisa Arias-Muñoz, Cristóbal Cerda-Troncoso, Susanne Bandau, Andrea Soza, Gudrun Kausel, Bredford Kerr, Gonzalo A Mardones, Jorge Cancino, Ronald T Hay, Alejandro Rojas-Fernandez, Patricia V Burgos
Publikováno v:
Cells, Vol 9, Iss 3, p 777 (2020)
Ubiquitination regulates several biological processes, however the role of specific members of the ubiquitinome on intracellular membrane trafficking is not yet fully understood. Here, we search for ubiquitin-related genes implicated in protein membr
Externí odkaz:
https://doaj.org/article/3634f2aa74524a4e98b8cc55c16c1814
Autor:
Viviana A Cavieres, Alexis González, Vanessa C Muñoz, Claudia P Yefi, Hianara A Bustamante, Rafael R Barraza, Cheril Tapia-Rojas, Carola Otth, María José Barrera, Carlos González, Gonzalo A Mardones, Nibaldo C Inestrosa, Patricia V Burgos
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136313 (2015)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-β (Aβ) peptide. We have previously shown that the compound tetrahydrohyperforin (IDN5706) prevents accumulation of Aβ species in an in vivo model
Externí odkaz:
https://doaj.org/article/9775bf90c9e94a3aba8e18681276dc3a
Autor:
Hianara A Bustamante, Andrés Rivera-Dictter, Viviana A Cavieres, Vanessa C Muñoz, Alexis González, Yimo Lin, Gonzalo A Mardones, Patricia V Burgos
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83096 (2013)
Alzheimer's disease (AD) is characterized by the buildup of amyloid-β peptides (Aβ) aggregates derived from proteolytic processing of the β-amyloid precursor protein (APP). Amyloidogenic cleavage of APP by β-secretase/BACE1 generates the C-termin
Externí odkaz:
https://doaj.org/article/85bed3ae004d4287a6f9f193c954a431
Autor:
Camila Pino-Belmar, Rayén Aguilar, Guillermo E. Valenzuela-Nieto, Viviana A. Cavieres, Cristóbal Cerda-Troncoso, Valentina C. Navarrete, Paula Salazar, Patricia V. Burgos, Carola Otth, Hianara A. Bustamante
Publikováno v:
Cells, Vol 13, Iss 15, p 1256 (2024)
Autophagy engulfs cellular components in double-membrane-bound autophagosomes for clearance and recycling after fusion with lysosomes. Thus, autophagy is a key process for maintaining proteostasis and a powerful cell-intrinsic host defense mechanism,
Externí odkaz:
https://doaj.org/article/ac44167cac1a4a3fbfa4e0f9e70127fe
Publikováno v:
Cellular signalling. 101
PSMD14/POH1/Rpn11 plays a crucial role in cellular homeostasis. PSMD14 is a structural subunit of the lid subcomplex of the proteasome 19S regulatory particle with constitutive deubiquitinase activity. Canonically, PSMD14 removes the full ubiquitin c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c8bc8ab830ad6395496fd280051806
https://pubmed.ncbi.nlm.nih.gov/36241058
https://pubmed.ncbi.nlm.nih.gov/36241058
Autor:
Gabriela Vargas, Omar Cortés, Eloisa Arias-Muñoz, Sergio Hernández, Cristobal Cerda-Troncoso, Laura Hernández, Alexis E. González, Michael H. Tatham, Hianara A. Bustamante, Claudio Retamal, Jorge Cancino, Manuel Varas-Godoy, Ronald T. Hay, Alejandro Rojas-Fernández, Viviana A. Cavieres, Patricia V. Burgos
Publikováno v:
Frontiers in Cell and Developmental Biology. 10
Macroautophagy and the ubiquitin proteasome system work as an interconnected network in the maintenance of cellular homeostasis. Indeed, efficient activation of macroautophagy upon nutritional deprivation is sustained by degradation of preexisting pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d571783b35330cea2cece6285ad100
https://doi.org/10.3389/fcell.2022.743287
https://doi.org/10.3389/fcell.2022.743287
Autor:
Ronald T. Hay, Alexis Gonzalez, Cortes Oh, Manuel Varas-Godoy, Hernandez-Galaz Sf, Patricia Burgos, Michael H. Tatham, Alejandro Rojas-Fernandez, Vargas G, Jorge Cancino, Hianara A. Bustamante, Cristóbal Cerda-Troncoso, Claudio Retamal, Hernandez-Torres L, Arias-Munoz En, Cavieres Va
Macroautophagy and the ubiquitin proteasome system work as an interconnected network in the maintenance of cellular homeostasis. Indeed, efficient activation of macroautophagy upon nutritional deprivation is sustained by degradation of preexisting pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::338374674c81efa94e6277cb8402b311
https://doi.org/10.1101/2021.06.14.447273
https://doi.org/10.1101/2021.06.14.447273
Autor:
Alexis E González, Yunan C Januário, Gonzalo A. Mardones, Vanessa C. Muñoz, Viviana A Cavieres, Patricia V. Burgos, Hianara A. Bustamante, Claudio Hetz, Luis L. P. daSilva, Ibeth González, Alejandro Rojas-Fernandez, Víctor-Hugo Cornejo, Ronald T. Hay
Publikováno v:
The Faseb Journal
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Brain regions affected by Alzheimer disease (AD) display well-recognized early neuropathologic features in the endolysosomal and autophagy systems of neurons, including enlargement of endosomal compartments, progressive accumulation of autophagic vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8143301e35d6e40d10818c78944c32af
https://doi.org/10.1096/fj.201600713r
https://doi.org/10.1096/fj.201600713r
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3379 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3379 (2019)
Proteasome inhibitors have been actively tested as potential anticancer drugs and in the treatment of inflammatory and autoimmune diseases. Unfortunately, cells adapt to survive in the presence of proteasome inhibitors activating a variety of cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ec4430bfae10a8935893ef89ba87f5
https://pubmed.ncbi.nlm.nih.gov/31295808
https://pubmed.ncbi.nlm.nih.gov/31295808
Autor:
Alejandro Rojas, Ronald T. Hay, G. Kausel, Guillermo Valenzuela, Alexis E González, Karina Cereceda, Patricia V. Burgos, Eloisa Arias, Jorge Cancino, Yorka Cheuquemilla, Hianara A. Bustamante, Cristóbal Cerda-Troncoso, Sergio Hernández, Susanne Bandau, Bredford Kerr, Andrea Soza, Gonzalo A. Mardones
Publikováno v:
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 777 (2020)
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 777 (2020)
Ubiquitination regulates several biological processes, however the role of specific members of the ubiquitinome on intracellular membrane trafficking is not yet fully understood. Here, we search for ubiquitin-related genes implicated in protein membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a584a105d13cf25c4986d981469472
https://doi.org/10.3390/cells9030777
https://doi.org/10.3390/cells9030777