Zobrazeno 1 - 10
of 114
pro vyhledávání: '"HiChIP"'
Autor:
Eva D’haene, Víctor López-Soriano, Pedro Manuel Martínez-García, Soraya Kalayanamontri, Alfredo Dueñas Rey, Ana Sousa-Ortega, Silvia Naranjo, Stijn Van de Sompele, Lies Vantomme, Quinten Mahieu, Sarah Vergult, Ana Neto, José Luis Gómez-Skarmeta, Juan Ramón Martínez-Morales, Miriam Bauwens, Juan Jesús Tena, Elfride De Baere
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Background Vision depends on the interplay between photoreceptor cells of the neural retina and the underlying retinal pigment epithelium (RPE). Most genes involved in inherited retinal diseases display specific spatiotemporal expression wit
Externí odkaz:
https://doaj.org/article/a3d8d2ce3b6a449b865a48720cdd33d6
Autor:
Kade P. Pettie, Maxwell Mumbach, Amanda J. Lea, Julien Ayroles, Howard Y. Chang, Maya Kasowski, Hunter B. Fraser
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Current evidence suggests that cis-regulatory elements controlling gene expression may be the predominant target of natural selection in humans and other species. Detecting selection acting on these elements is critical to underst
Externí odkaz:
https://doaj.org/article/029208ac9127460faeb7e0e1b32c4b4f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 931-939 (2023)
High-throughput chromatin conformation capture technologies, such as Hi-C and Micro-C, have enabled genome-wide view of chromatin spatial organization. Most recently, Hi-C-derived enrichment-based technologies, including HiChIP and PLAC-seq, offer at
Externí odkaz:
https://doaj.org/article/90edf465ee8645e48e6847001a777ba9
Autor:
Jingjin Li, Yue Xiang, Lu Zhang, Xiaolong Qi, Zhuqing Zheng, Peng Zhou, Zhenshuang Tang, Yi Jin, Qiulin Zhao, Yuhua Fu, Yunxia Zhao, Xinyun Li, Liangliang Fu, Shuhong Zhao
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Gene expression programs are intimately linked to the interplay of active cis regulatory elements mediated by chromatin contacts and associated RNAs. Genome-wide association studies (GWAS) have identified many variants in these re
Externí odkaz:
https://doaj.org/article/26edad5b00bd491a8cf952267d1ac207
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Chromatin conformation capture (3C)-based technologies have enabled the accurate detection of topological genomic interactions, and the adoption of ChIP techniques to 3C-based protocols makes it possible to identify long-range interactions.
Externí odkaz:
https://doaj.org/article/e9ca690c41f742d1b3baf63353c1e3d2
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Jonathan D. Rosen, Yuchen Yang, Armen Abnousi, Jiawen Chen, Michael Song, Ian R. Jones, Yin Shen, Ming Hu, Yun Li
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 1156-1170 (2021)
HiChIP and PLAC-Seq are emerging technologies for studying genome-wide long-range chromatin interactions mediated by the protein of interest, enabling more sensitive and cost-efficient interrogation of protein-centric chromatin conformation. However,
Externí odkaz:
https://doaj.org/article/a59ca0fb7f4a47158be9c67a65b04b56
Autor:
James S. Smith, Katrina M. Lappin, Stephanie G. Craig, Fabio G. Liberante, Clare M. Crean, Simon S. McDade, Alexander Thompson, Ken I. Mills, Kienan I. Savage
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background The cohesin complex plays a major role in folding the human genome into 3D structural domains. Mutations in members of the cohesin complex are known early drivers of myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML
Externí odkaz:
https://doaj.org/article/3da9f9f6b1b142149744239d66e7c7a9
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract We present Mustache, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps. Mu
Externí odkaz:
https://doaj.org/article/98b8ae8643c14d5fa0d862a04635b1c0