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Autor:
Byumseok Koh, Dahee Kim, Kwang Rok Kim, Sungsub Kim, Sang Dal Rhee, Won Hoon Jung, Ki-Young Kim, Hi Youn Kim
Publikováno v:
Oncology Letters
XAV939, a tankyrase inhibitor, exerts an anticancer effect in 3-dimensional (3D) cultured SW480 cells, however this is not exhibited in 2-dimensional (2D) cultured SW480 cells. In the current study, XAV939 induced a 3.7-fold increase in cellular apop