Zobrazeno 1 - 10
of 4 209
pro vyhledávání: '"Hi‐C"'
Autor:
Mateusz Chiliński, Dariusz Plewczynski
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Prediction of chromatin interactions from DNA sequence has been a significant research challenge in the last couple of years. Several solutions have been proposed, most of which are based on encoder-decoder architecture, where 1D sequence is
Externí odkaz:
https://doaj.org/article/c7b7196adf184ba6a41bcce9375e5cb0
Autor:
Mir Henglin, Maryam Ghareghani, William T. Harvey, David Porubsky, Sergey Koren, Evan E. Eichler, Peter Ebert, Tobias Marschall
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Haplotype information is crucial for biomedical and population genetics research. However, current strategies to produce de novo haplotype-resolved assemblies often require either difficult-to-acquire parental data or an intermediate haploty
Externí odkaz:
https://doaj.org/article/3512fe7340b944e4bcccd787429f9cff
Publikováno v:
BMC Genomics, Vol 22, Iss S5, Pp 1-12 (2024)
Abstract Background Cell type prediction is crucial to cell type identification of genomics, cancer diagnosis and drug development, and it can solve the time-consuming and difficult problem of cell classification in biological experiments. Therefore,
Externí odkaz:
https://doaj.org/article/cb4ba368a9b54ed68f3d55cbd3eafe15
Autor:
Xiaoyan Zhu, Yi Yang, Qiuyao Li, Jing Li, Lin Du, Yanhan Zhou, Hongbo Jin, Liwen Song, Qi Chen, Bingzhong Ren
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Baryscapus dioryctriae (Chalcidodea: Eulophidae) is a parasitic wasp that parasitizes the pupae of many Pyralidae members and has been used as a biological control agent against Dioryctria pests of pinecones. Results This B. diory
Externí odkaz:
https://doaj.org/article/9162ed31082f404592ef3db220304376
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Chromosome organization plays an important role in biological processes such as replication, regulation, and transcription. One way to study the relationship between chromosome structure and its biological functions is through Hi-
Externí odkaz:
https://doaj.org/article/b20881c1c94c4b09a32b7406e4c0ff5f
Autor:
Sean M. Flynn, Somdutta Dhir, Krzysztof Herka, Colm Doyle, Larry Melidis, Angela Simeone, Winnie W. I. Hui, Rafael de Cesaris Araujo Tavares, Stefan Schoenfelder, David Tannahill, Shankar Balasubramanian
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization. However, such methods do not capture the possible involvement of other epigenomic
Externí odkaz:
https://doaj.org/article/64f8f18f52c349d5bcf820beb8d79a27
Autor:
Akanksha Rajput, Colleen Reilly, Airen Zaldivar Peraza, Jian Wang, Edgar Sioson, Gavriel Matt, Robin Paul, Congyu Lu, Aleksandar Acic, Karishma Gangwani, Xin Zhou
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3467-3471 (2024)
The ProteinPaint Hi-C tool (ppHiC) facilitates web-based visualization and collaborative exploration of Hi-C data, a vital resource for understanding three-dimensional genomic structures. ppHiC allows researchers to easily analyze large Hi-C datasets
Externí odkaz:
https://doaj.org/article/2709347619be4a0a91221077b9e73e36
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1584-1593 (2024)
For many years, multi-scale models of chromatin domains, such as A/B compartments, sub-compartments, topologically associated domains (TADs), sub-TADs, and loops have been popular. However, existing methods can only identify structures at a single sc
Externí odkaz:
https://doaj.org/article/44e309a698a84d3abd66c2f8e1981d7f
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Background Understanding the interactions and dynamics of microbiotas within biological wastewater treatment systems is essential for ensuring their stability and long-term sustainability. In this study, we developed a systematic framework e
Externí odkaz:
https://doaj.org/article/e2cdf907a30d4fa8b89d44979c20c6c2
Autor:
Hang Yan, Yunhao Zhu, Haoyu Jia, Yuanjun Li, Yongguang Han, Xiaoke Zheng, Xiule Yue, Le Zhao, Weisheng Feng
Publikováno v:
BMC Genomic Data, Vol 25, Iss 1, Pp 1-4 (2024)
Abstract Objectives As a traditional Chinese medicine, Lepidium apetalum is commonly used for purging the lung, relieving dyspnea, alleviating edema, and has the significant pharmacological effects on cardiovascular disease, hyperlipidemia, etc. In a
Externí odkaz:
https://doaj.org/article/86ccd160a85b4bc99c459e413bcfdb14