Zobrazeno 1 - 10 of 496 pro vyhledávání: '"Hg, Drexler"'
1
MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines
Autor: Corinna Meyer, Stefan Nagel, R A F MacLeod, Hilmar Quentmeier, Maren Kaufmann, HG Drexler
Publikováno v: Leukemia. 22:600-607
In T-cell acute lymphoblastic leukemia (T-ALL) the cardiac homeobox gene NKX2-5 (at 5q35) is variously deregulated by regulatory elements coordinating with BCL11B (at 14q32.2), or the T-cell receptor gene TRD (at 14q11.2), respectively. NKX2-5 is nor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916a4c0a5dc3bb873ec5a1a384fa7d88
https://doi.org/10.1038/sj.leu.2405067
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2
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
Autor: Roland Eils, Anke K. Bergmann, Marta Kulis, Volker Hovestadt, Roderick A. F. MacLeod, Andrea Haake, Bernhard Radlwimmer, Simone Picelli, Ralf Küppers, Siegfried Haas, Hendrik G. Stunnenberg, Sonja Eberth, Lorenz Trümper, Peter F. Stadler, Judith Arnolds, Maciej Rosolowski, Peter Lichter, Stephan H. Bernhart, Michael Hummel, Hinrik H.D. Kerstens, Matthias Schlesner, Birgit Burkhardt, Bingding Huang, Cristina López, Inga Nagel, Monika Szczepanowski, Markus Loeffler, Enrique Carrillo-de-Santa-Pau, Jana Gutwein, Marius Rohde, Frank Jühling, Qianhao Lu, Dido Lenze, Rabea Wagener, Julia Kolarova, Markus Kreuz, Peter Möller, Wolfram Klapper, Paul Flicek, Robert B. Russell, Wei Wang, Steve Hoffmann, Joost H.A. Martens, Marc A. Weniger, Markus Schilhabel, HG Drexler, Alexander Claviez, Julia Richter, Matthew J. Betts, Philip Rosenstiel, Inga Vater, Chris Lawerenz, Ole Ammerpohl, José I. Martín-Subero, Christian Otto, Daniel Rico, Gero Doose, Reiner Siebert, Helene Kretzmer, Dennis Karsch
Publikováno v: Nature Genetics, 47, 1316-1325
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Genetics, 47, 11, pp. 1316-1325
Although Burkitt lymphomas and follicular lymphomas both have features of germinal center B cells, they are biologically and clinically quite distinct. Here we performed whole-genome bisulfite, genome and transcriptome sequencing in 13 IG-MYC translo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d150729c6058f25ccd8ef3270a893e7
http://hdl.handle.net/2066/149282
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3
STAG2 (Stromal Antigen 2)
Autor: Suning Chen, Stefan Nagel, Raf MacLeod, HG Drexler
Publikováno v: Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Review on STAG2, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::925b4ebdbc22a110ab1812b565bb6e4f
https://doi.org/10.4267/2042/53538
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4
False human hematopoietic cell lines: cross-contaminations and misinterpretations
Autor: R A F MacLeod, HG Drexler, W. G. Dirks
Publikováno v: Leukemia. 13:1601-1607
The risk of adventitious contamination and subsequent overgrowth of cell lines by unrelated cells is a potential and often recurring problem where cells are grown and studied. This problem of intraspecies and interspecies cross-contamination among hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd188d662835228a8eef3a9126ac4a6
https://doi.org/10.1038/sj.leu.2401510
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8
In vitro beta2-microglobulin (β2m) secretion by normal and leukaemic B-cells: effects of recombinant cytokines and evidence for a differential response to the combined stimulus of phorbol ester and calcium ionophore
Autor: SM Gignac, HG Drexler, CS Scott, JA Child, RA Jones
Publikováno v: British Journal of Cancer
Due to the increasing therapeutic use of immunoregulatory agents and the potential effects on cellular function, we examined the modulation of in vitro beta 2-microglobulin (beta 2m) production rates by 'normal' tonsil and leukaemic B-cells in respon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8fd8f4f7624a123b1fef957e3afddf
https://doi.org/10.1038/bjc.1990.153
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9
HHV-8 infection is specific for cell lines derived from primary effusion (body cavity-based) lymphomas
Autor: CC Uphoff, S Habig, A Carbone, G Gaidano, HG Drexler
Publikováno v: Leukemia. 12(11)
Human herpes virus 8 (HHV-8; or KSHV, Kaposi's sarcoma-associated herpes virus) is a gamma herpes virus with sequence homology to Epstein-Barr virus (EBV). It was first isolated from Kaposi's sarcoma tumor cells and subsequently from tumor cells and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661c31f3242a2a650c35229c277d8706
https://pubmed.ncbi.nlm.nih.gov/9823957
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10
Aberrant Chromatin Modifications Mediate Ectopic Expression of Homeobox Gene NKX2-1 in B-Cell Lymphoma
Autor: Roderick A. F. MacLeod, Stefan Nagel, HG Drexler, Corinna Meyer, Maren Kaufmann
Publikováno v: Blood. 120:3494-3494
Abstract 3494 Homeobox genes encode transcription factors ubiquitously involved in basic developmental processes, and when deregulated promote cell transformation in multiple cancers including hematopoietic malignancies. In this context several membe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89950c0bd6c5ab3269723336c5626d5e
https://doi.org/10.1182/blood.v120.21.3494.3494
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