Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Heyne Lee"'
Autor:
Walther Haenseler, Federico Zambon, Heyne Lee, Jane Vowles, Federica Rinaldi, Galbha Duggal, Henry Houlden, Katrina Gwinn, Selina Wray, Kelvin C. Luk, Richard Wade-Martins, William S. James, Sally A. Cowley
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract To examine the pathogenic role of α-synuclein (αS) in Parkinson’s Disease, we have generated induced Pluripotent Stem Cell lines from early onset Parkinson’s Disease patients with SNCA A53T and SNCA Triplication mutations, and in this
Externí odkaz:
https://doaj.org/article/079e9c373cb245c5abd9ca8f629f34fc
Autor:
Ilse S. Pienaar, Cecilia Heyne Lee, Joanna L. Elson, Louisa McGuinness, Stephen M. Gentleman, Raj N. Kalaria, David T. Dexter
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 392-405 (2015)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an accepted treatment for motor symptoms in a subset of Parkinson's disease (PD) patients. The mechanisms why DBS is effective are incompletely understood, but previous studies
Externí odkaz:
https://doaj.org/article/86cbc8150e8048b786c474f66ca51211
Autor:
Phillippa J. Carling, William James, Rowan Flynn, Walther Haenseler, Monika Stegmann, Jane Vowles, Heyne Lee, Sally A. Cowley, Francesca J. Nicholls, Ishta Sharma, Emma R. Haberman, Richard Wade-Martins
Publikováno v:
Stem Cell Reports
Summary The Parkinson's disease-associated gene, LRRK2, is also associated with immune disorders and infectious disease and is expressed in immune subsets. Here, we characterize a platform for interrogating the expression and function of endogenous L
Autor:
Peter Reinhardt, Alfredo Cabrera Socorro, Eric G. Mohler, Margot H.M. Bakker, Marco Rocha Curado, Francesco V. Rao, Janina S. Ried, Laura Madrid, Armel Nicolas, Lamiaa Bahnassawy, Clara Grezella, Gayathri Ramaswamy, María Eugenia Sáez, Heyne Lee
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Janina S. Ried, Heyne Lee, Marco Rocha Curado, Clara Grezella, Armel Nicolas, Gayathri Ramaswamy, María Eugenia Sáez, Lamiaa Bahnassawy, Laura Madrid, Eric G. Mohler, Francesco V. Rao, Peter Reinhardt, Alfredo Cabrera Socorro, Margot H.M. Bakker
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Viktor Lakics, Margot H.M. Bakker, Gayathri Ramaswamy, Janina S. Ried, Francesco V. Rao, Lamiaa Bahnassawy, María Eugenia Sáez, Juergen Korffmann, Oliver Brüstle, Clara Grezella, Marco Rocha Curado, Heyne Lee, M Cik, Armel Nicolas, Michael Peitz, Eric G. Mohler, Peter Reinhardt, Alfredo Cabrera Socorro, Johanna Buchheit, Charlotte Kaplan, Christopher Untucht, Santos Mañes
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Ishta Sharma, Richard Wade-Martins, Phillippa J. Carling, Francesca J. Nicholls, Sally A. Cowley, William James, Rowan Flynn, Jane Vowles, Heyne Lee, Monika Stegmann
SummaryThe Parkinson’s disease-associated gene, LRRK2, is also associated with immune disorders and infectious disease, and is expressed in immune subsets. Here, we characterise a platform for interrogating the expression and function of endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f1353d7e878f7e9b17fd8cc0c1dc10
Autor:
Brian D. Dill, Paul Davies, Ian G. Ganley, Maximiliano G. Gutierrez, Susanne Herbst, Patrick A. Lewis, Jennifer Martinez, Sally A. Cowley, Heyne Lee, Dario R. Alessi, Anetta Härtlova, Angela Rodgers, Alastair D. Reith, Julien Peltier, Orsolya Bilkei-Gorzo, Matthias Trost, Antony Fearns, Rowan Flynn
Publikováno v:
Embo Journal
Mutations in the leucine-rich repeat kinase 2 (LRRK2) are associ- ated with Parkinson’s disease, chronic inflammation and mycobac- terial infections. Although there is evidence supporting the idea that LRRK2 has an immune function, the cellular fun
Autor:
Anetta, Härtlova, Susanne, Herbst, Julien, Peltier, Angela, Rodgers, Orsolya, Bilkei-Gorzo, Antony, Fearns, Brian D, Dill, Heyne, Lee, Rowan, Flynn, Sally A, Cowley, Paul, Davies, Patrick A, Lewis, Ian G, Ganley, Jennifer, Martinez, Dario R, Alessi, Alastair D, Reith, Matthias, Trost, Maximiliano G, Gutierrez
Publikováno v:
The EMBO Journal
Mutations in the leucine‐rich repeat kinase 2 (LRRK2) are associated with Parkinson's disease, chronic inflammation and mycobacterial infections. Although there is evidence supporting the idea that LRRK2 has an immune function, the cellular functio
Autor:
Stephen M. Gentleman, Louisa McGuinness, Ilse S. Pienaar, Cecilia Heyne Lee, David T. Dexter, Raj N. Kalaria, Joanna L. Elson
Publikováno v:
Neurobiology of Disease, Vol 74, Iss, Pp 392-405 (2015)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an accepted treatment for motor symptoms in a subset of Parkinson's disease (PD) patients. The mechanisms why DBS is effective are incompletely understood, but previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5e38c3303616026e3bf4e000ce193a
http://hdl.handle.net/10044/1/19683
http://hdl.handle.net/10044/1/19683