Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Heying Pei"'
Autor:
Mengshi Hu, Tao Yang, Linyu Yang, Lu Niu, Jinbing Zhu, Ailin Zhao, Mingsong Shi, Xue Yuan, Minghai Tang, Jianhong Yang, Heying Pei, Zhuang Yang, Qiang Chen, Haoyu Ye, Ting Niu, Lijuan Chen
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/6aeb2b5162d94e52bba8affde5d0b2f5
Autor:
Zejiang Zhu, Jiaolin Wen, Yaohui Xu, Heying Pei, Dan Li, Minghai Tang, Peng Bai, Jun He, Zhuang Yang, Lijuan Chen
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 743-753 (2022)
Background: Previous studies have proven that Purinostat Mesylate (PM) is a new HDAC inhibitor and exhibits significant antitumor efficacy. However, the clinical application of PM was greatly limited by its poor solubility in water and low bioavailab
Externí odkaz:
https://doaj.org/article/79621c5371944ab3ab0dc32252cd9bfa
Autor:
Mengshi Hu, Tao Yang, Linyu Yang, Lu Niu, Jinbing Zhu, Ailin Zhao, Mingsong Shi, Xue Yuan, Minghai Tang, Jianhong Yang, Heying Pei, Zhuang Yang, Qiang Chen, Haoyu Ye, Ting Niu, Lijuan Chen
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 3, Pp 1-13 (2022)
Abstract Janus kinase 2 (JAK2) hyperactivation by JAK2 V617F mutation leads to myeloproliferative neoplasms (MPNs) and targeting JAK2 could serve as a promising therapeutic strategy for MPNs. Here, we report that Flonoltinib Maleate (FM), a selective
Externí odkaz:
https://doaj.org/article/ee4d744644724e00a080c51ba6c16a47
Autor:
Jianyu Liu, Minghai Tang, Tao Li, Zhengying Su, Zejiang Zhu, Caixia Dou, Yan Liu, Heying Pei, Jianhong Yang, Haoyu Ye, Lijuan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/62b2acb3e46243b9928d4c0135d3e767
Autor:
Jianyu Liu, Minghai Tang, Tao Li, Zhengying Su, Zejiang Zhu, Caixia Dou, Yan Liu, Heying Pei, Jianhong Yang, Haoyu Ye, Lijuan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Post-myocardial infarction heart failure (post-MI HF) is one of the leading global causes of death, and current prevention and treatment methods still cannot avoid the increasing incidence. Honokiol (HK) has previously been reported to improve myocar
Externí odkaz:
https://doaj.org/article/3e23cf59dba741579293435566af7014
Autor:
Jiali Zhu, Tao Yang, Minghai Tang, Zhuang Yang, Heying Pei, Haoyu Ye, Yu Tang, Zhixuan Cheng, Ping Lin, Lijuan Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111373- (2021)
Psoriasis is a chronic, inflammatory autoimmune disease mediated by T cells, and characterized with abnormal proliferation and differentiation of keratinocytes, and inflammatory infiltration. The Janus kinase-signal transducer and activator of transc
Externí odkaz:
https://doaj.org/article/b9b20243def641058ae4ae274b15da2c
Autor:
Jiaolin Wen, Xianhuo Wang, Heying Pei, Caifeng Xie, Neng Qiu, Shucai Li, Wenwen Wang, Xia Cheng, Lijuan Chen
Publikováno v:
Journal of Pharmacological Sciences, Vol 128, Iss 3, Pp 116-124 (2015)
Honokiol (HK), a biphenolic neolignan isolated from Magnolia officinalis, has been reported to possess anti-inflammatory and anti-angiogenic activaties. In this study, our aim was to investigate anti-psoriatic activities of HK and the involved mechan
Externí odkaz:
https://doaj.org/article/1a0ff7bf0dcf43ae93eb615fad59ac9c
Autor:
Liang Ma, Li Huang, Heying Pei, Zhuowei Liu, Caifeng Xie, Lei Lei, Xiaoxin Chen, Haoyu Ye, Aihua Peng, Lijuan Chen
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 14687-14698 (2014)
Mai Tong Fang (MTF), a Chinese herbal combination, has been used for the treatment of diabetic nephropathy in traditional medical clinics in China. However, the anti-adipogenic and anti-hyperglycemic effects of MTF have not been fully elucidated, so
Externí odkaz:
https://doaj.org/article/dad124d5f131494093780d4dbb1496ea
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 6163-6183 (2014)
Leptin, the product of the obese gene, is an adipocyte-secreted protein hormone playing a key role in the progression of obesity and hepatic steatosis. In this study, 28 novel (thio)urea and guanidine-based analogues have been synthesized and N-(1-(4
Externí odkaz:
https://doaj.org/article/7ae9ab632ac24df5820a44d67e2e7cf3
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56349 (2013)
Rheumatoid arthritis (RA) is the most common arthritis and is mainly characterized by symmetric polyarticular joint disorders. Our previous study demonstrated a novel small molecule compound (Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin-5-yliden
Externí odkaz:
https://doaj.org/article/5dfe4dcda59f47029e5ff83591212267