Výsledky vyhledávání

LncRNA SOCS2-AS1 inhibits progression and metastasis of colorectal cancer through stabilizing SOCS2 and sponging miR-1264

Autor: Heyi You, Xiaoxiao Li, Xiaojiao Ruan, Zhihai Zheng, Xiaofeng Zheng

Publikováno v: Aging (Albany NY)

Abnormal expression of long noncoding RNA (lncRNA) is involved in human cancers, including colorectal cancer (CRC). However, their functional mechanism is largely unknown. In this study, we explored the roles of lncRNA SOCS2-AS1 in modulating CRC pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13341819a4d31b8a23becba48a8ffeb7
https://pubmed.ncbi.nlm.nih.gov/32437330

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Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer

Autor: Jinfu Tu, Heyi You, Bingren Hu, Xue-Meng Xie

Publikováno v: Drug Design, Development and Therapy. 11:1439-1451

Given the important role that inhibitory kappa B (IκB) kinase β (IKKβ) plays in pancreatic cancer (PC) development and progression, inhibitors targeting IKKβ are believed to be increasingly popular as novel anti-PC therapies. Two synthetic molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f483d2afb53249a64e5a38b8b32ff6e
https://doi.org/10.2147/dddt.s133172

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Interleukin-32α inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial–mesenchymal transition, invasion, and metastasis in pancreatic cancer cells

Autor: Mengtao Zhou, Heyi You, Zongjing Chen, Bicheng Chen, Hongwei Sun, Jiadong Su, Silu Wang, Jingfeng Chen, Guanyu Chu

Publikováno v: OncoTargets and therapy

Jingfeng Chen,1,2,* Silu Wang,1,* Jiadong Su,1 Guanyu Chu,1 Heyi You,1 Zongjing Chen,1 Hongwei Sun,1 Bicheng Chen,1,3 Mengtao Zhou1 1Department of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 2Department of Surgery,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae23307a837e4cd75ccb603fbd84106c
https://doi.org/10.2147/ott.s103581

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Akademický článek

Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer.

Autor: Xuemeng Xie, Jinfu Tu, Heyi You, Bingren Hu

Publikováno v: Drug Design, Development & Therapy; 2017, Vol. 11, p1439-1451, 13p

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Promotion of Metastasis-associated Gene Expression in Survived PANC-1 Cells Following Trichostatin A Treatment

Autor: Benquan Wang, Heyi You, Meng Sun, Zongjing Chen, Yunxiu Yang, Bicheng Chen, Ling Zhang, Mengtao Zhou, Biao Liu

Publikováno v: Anti-cancer agents in medicinal chemistry. 15(10)

Objectives: Histone deacetylase inhibitors represent a promising class of potential anticancer agents for the treatment of human malignancies. In this study, the effects of trichostatin A (TSA) on apoptosis, metastasis-associated gene expression, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbf7505952e1e5e2a0e8cfee7877d6c
https://pubmed.ncbi.nlm.nih.gov/25991546

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Akademický článek

The Truth and Reconciliation Commission and gender: The Testimony of Mrs Konile revisited.

Autor: Kobe, Sandiswa L.^1,2 u16401116@tuks.co.za

Publikováno v: Hervormde Teologiese Studies. 2017, Vol. 73 Issue 3, p1-8. 8p.

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Akademický článek

Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer

Autor: Xie X, Tu J, You H, Hu B

Publikováno v: Drug Design, Development and Therapy, Vol Volume 11, Pp 1439-1451 (2017)

Xuemeng Xie, Jinfu Tu, Heyi You, Bingren Hu Department of Laparoscopic Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China Abstract: Given the important role that inhibitory kappa B (IκB)

Externí odkaz: https://doaj.org/article/adc3b8c5d88c4a67ab54ad1105e228ef

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