Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Heyao Wang"'
Autor:
Minmin Zhang, Yun Fan, Xueliang Wang, Jinghua Wang, Rong Chen, Husheng Pan, Yanqun Xiao, Heyao Wang, Weigang Huang, Hualiang Wang
Publikováno v:
View, Vol 5, Iss 2, Pp n/a-n/a (2024)
Abstract Rabies is a lethal infectious disease caused by rabies virus (RABV). The mortality rate is very high after the appearance of clinical symptoms, with a survival rate of almost 0%. There is presently no cure for rabies. In the present study, w
Externí odkaz:
https://doaj.org/article/2ce02675379d4d92b22eb9fe96338da5
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113981- (2022)
Hydroxyeicosatetraenoic acids (HETEs) are metabolites of arachidonate acid (AA) oxidized by lipoxygenases or cytochrome P450 enzymes (CYP450). Since lipoxygenases and CYP450 enzymes widely exist in different organs and tissues, HETEs play significant
Externí odkaz:
https://doaj.org/article/443d23e6fffd4a3cabff5429b5914308
Autor:
Yiping Zhu, Dandan Yin, Yali Su, Xuyang Xia, Takaya Moriyama, Rina Nishii, Fei Liao, Shouyue Zhang, Xia Guo, Qianqian Hou, Yuan Ai, Xueyan Zhou, Shuwen Sun, Duyu Zhang, Yan Zhang, Chao Lin, Yiqi Deng, Xiaoxi Lu, Yuelan Wang, Zhigui Ma, Heyao Wang, Bo Liu, Li Yang, Wei Zhang, Jun J. Yang, Yang Shu, Ju Gao, Heng Xu
Publikováno v:
Haematologica, Vol 103, Iss 7 (2018)
Externí odkaz:
https://doaj.org/article/0b8ffb33d5264394851cf9428d3791bf
Publikováno v:
Molecules, Vol 23, Iss 12, p 3318 (2018)
This study investigated the possible enhancement of berberine’s (BB) hypoglycemic activity by oligomeric proanthocyanidins (OPCs) and its underlying mechanism. The hypoglycemic activity of the studied compounds was evaluated in diabetic db/db mice.
Externí odkaz:
https://doaj.org/article/abe2c74d2ef546a7878a5ad31cb622a0
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132411 (2015)
Lipotoxicity plays an important role in pancreatic β-cell failure during the development of type 2 diabetes. Prolonged exposure of β-cells to elevated free fatty acids level could cause deterioration of β-cell function and induce cell apoptosis. T
Externí odkaz:
https://doaj.org/article/0c7fcc5127084bd18a6955b81291cf19
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66744 (2013)
G protein-coupled receptor 40 (GPR40) mediates both acute and chronic effects of free fatty acids (FFAs) on insulin secretion. However, it remains controversial whether inhibition of GPR40 would be beneficial in prevention of type 2 diabetes. This st
Externí odkaz:
https://doaj.org/article/a53542f5ffd74f059489f804e6d9ee9a
Autor:
Yulong He, Shunyi Li, Yueyue Zhu, Yujie Wang, Yuqi Chen, Deqiang Zhang, Heyao Wang, Yingxia Li
Publikováno v:
European Journal of Medicinal Chemistry. 253:115319
Publikováno v:
Chinese Journal of Organic Chemistry. 43:636
Autor:
Xu Xu, Te Du, Xi Huang, Xiaofan Shi, Liu Yang, Lihong Hu, Xin Xu, Ji-Ming Ye, Heyao Wang, Jianlu Lv, Xu Shen, Jian Lu, Jing Chen
Publikováno v:
Journal of Endocrinology. 240:195-214
Vincamine, a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle, is clinically used for the treatment of cardio-cerebrovascular diseases, while also treated as a dietary supplement with nootropic function. Given the neuronal prote
Autor:
Yan Zhang, Bo Liu, Zhigui Ma, Xuyang Xia, Wei Zhang, Heyao Wang, Yiping Zhu, Y. Wang, Ge Zhang, Fei Liao, Hong Wang, Qianqian Hou, Lanlan Wang, Xue Yang, Shouyue Zhang, Yang Shu, Junlong Zhang, Heng Xu, Dandan Yin
Publikováno v:
Oncotarget
Thiopurines are widely used as anticancer and immunosuppressive agents. However, life-threatening myelotoxicity has been noticed and largely explained by genetic variations, including NUDT15 polymorphisms (e.g., rs116855232). In this study, we conduc