Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Hewitson Jp"'
Autor:
Johnston, CJC, Smyth, DJ, Kodali, RB, White, MPJ, Harcus, Y, Filbey, KJ, Hewitson, JP, Hinck, CS, Ivens, A, Kemter, AM, Kildemoes, AO, Le, Bihan T, Soares, DC, Maizels, RM
Publikováno v:
Johnston, CJC, Smyth, DJ, Kodali, RB, White, MPJ, Harcus, Y, Filbey, KJ, Hewitson, JP, Hinck, CS, Ivens, A, Kemter, AM, Kildemoes, AO, Le, B T, Soares, DC & Maizels, RM 2017, ' A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells. ', Nature Communications . https://doi.org/10.1038/s41467-017-01886-6
Helminth parasites defy immune exclusion through sophisticated evasion mechanisms, including activation of host immunosuppressive regulatory T (Treg) cells. The mouse parasite Heligmosomoides polygyrus can expand the host Treg population by secreting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::a37d155afa03114f6fde3f5aaaecd18b
https://www.research.manchester.ac.uk/portal/en/publications/a-structurally-distinct-tgf-mimic-from-an-intestinal-helminth-parasite-potently-induces-regulatory-t-cells(ad6e920a-523f-49e6-a361-65aaab1d7c20).html
https://www.research.manchester.ac.uk/portal/en/publications/a-structurally-distinct-tgf-mimic-from-an-intestinal-helminth-parasite-potently-induces-regulatory-t-cells(ad6e920a-523f-49e6-a361-65aaab1d7c20).html
Autor:
Osbourn, M, Soares, DC, Vacca, F, Cohen, ES, Scott, IC, Gregory, WF, Smyth, DJ, Toivakka, M, Kemter, AM, le, Bihan T, Wear, M, Hoving, D, Filbey, KJ, Hewitson, JP, McSorley, HJ
Publikováno v:
Osbourn, M, Soares, DC, Vacca, F, Cohen, ES, Scott, IC, Gregory, WF, Smyth, DJ, Toivakka, M, Kemter, AM, le, B T, Wear, M, Hoving, D, Filbey, KJ, Hewitson, JP & McSorley, HJ 2017, ' HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33. ', Immunity . https://doi.org/10.1016/j.immuni.2017.09.015
Infection by helminth parasites is associated with amelioration of allergic reactivity, but mechanistic insights into this association are lacking. Products secreted by the mouse parasite Heligmosomoides polygyrus suppress type 2 (allergic) immune re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::020145deedcbf65e139b1106cb83fe05
https://doi.org/10.1016/j.immuni.2017.09.015
https://doi.org/10.1016/j.immuni.2017.09.015
Autor:
Rode, H, Fieggen, AG, Brown, RA, Cywes, S, Davies, MRQ, Hewitson, JP, Hoffman, EB, Jee, LD, Lawrenson, J, Mann, MD, Matthews, LS, Millar, AJW, Numanoglu, A, Peter, JC, Thomas, J, Wainwright, H
Publikováno v:
South African Medical Journal
South African Medical Journal; Vol 96, No 9 (2006): Part 2; 931-940
South African Medical Journal; Vol 96, No 9 (2006): Part 2; 931-940
Conjoined twins represent a rare but fascinating congenital condition, the aetiology of which remains obscure. Over the past four decades, the paediatric surgeons at Red Cross Children's Hospital have been involved in the management of 46 pairs of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6fb3311e85f83a8b06bae44d64f29e8a
http://hdl.handle.net/11427/16549
http://hdl.handle.net/11427/16549
Autor:
Hewitson Jp, von Oppell Uo
Publikováno v:
World journal of surgery. 21(5)
Lymphadenopathy is the hallmark of intrathoracic tuberculosis in children. The role of the thoracic surgeon in treating childhood tuberculosis is to relieve the more severe symptoms of lymphadenopathy, prevent the more long-term secondary damage that
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Grainger, Smith, KA, Hewitson, JP, McSorley, HJ, Harcus, Y, Filbey, KJ, Finney, CAM, Greenwood, EJD, Knox, DP, Wilson, MS, Belkaid, Y, Rudensky, AY, Maizels, RM
Foxp3-expressing regulatory T (T reg) cells have been implicated in parasite-driven inhibition of host immunity during chronic infection. We addressed whether parasites can directly induce T reg cells. Foxp3 expression was stimulated in naive Foxp3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320bb677ba31fcad9bf8aa33b8e76042
Autor:
Greenman JH; Department of Biology, University of York, Heslington, York, United Kingdom; York Biomedical Research Institute, University of York, Heslington, York, United Kingdom., Moss L; Department of Biology, University of York, Heslington, York, United Kingdom; York Biomedical Research Institute, University of York, Heslington, York, United Kingdom., Chakraborty S; Department of Biology, University of York, Heslington, York, United Kingdom; York Biomedical Research Institute, University of York, Heslington, York, United Kingdom., Whitehead BJ; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark., Palmfedt J; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Nejsum P; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark., Hewitson JP; Department of Biology, University of York, Heslington, York, United Kingdom; York Biomedical Research Institute, University of York, Heslington, York, United Kingdom. Electronic address: james.hewitson@york.ac.uk., Hitchcock IS; Department of Biology, University of York, Heslington, York, United Kingdom; York Biomedical Research Institute, University of York, Heslington, York, United Kingdom. Electronic address: Ian.hitchcock@york.ac.uk.
Publikováno v:
Experimental hematology [Exp Hematol] 2024 Nov 29; Vol. 142, pp. 104689. Date of Electronic Publication: 2024 Nov 29.
Autor:
Kay AG; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom., Fox JM; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom., Hewitson JP; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom., Stone AP; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom., Robertson S; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom., James S; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom., Wang XN; Translational and Clinical Research Institute, Newcastle University, Newcastle, United Kingdom., Kapasa E; Department of Oral Biology, School of Dentistry, University of Leeds, St James's University Hospital, Leeds, United Kingdom., Yang XB; Department of Oral Biology, School of Dentistry, University of Leeds, St James's University Hospital, Leeds, United Kingdom., Genever PG; York Biomedical Research Institute and Department of Biology, University of York, York, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2022 Dec 13; Vol. 13, pp. 1111042. Date of Electronic Publication: 2022 Dec 13 (Print Publication: 2022).