Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial.

Autor: Machiels JP; Institut Roi Albert II, Cliniques universitaires Saint-Luc and Institut de Recherche Clinique et Expérimentale (Pole MIRO), UCLouvain, Brussels, Belgium. Electronic address: jean-pascal.machiels@saintluc.uclouvain.be., Tao Y; Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France., Licitra L; Fondazione IRCCS Istituto Nazionale dei Tumori and University of Milan, Milan, Italy., Burtness B; Department of Medicine and Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USA., Tahara M; National Cancer Center Hospital East, Kashiwa, Japan., Rischin D; Department of Medical Oncology, Peter MacCallum Cancer Centre and the University of Melbourne, Melbourne, VIC, Australia., Alves G; Centro Integrado de Pesquisa em Oncologia, Hospital Nossa Senhora de Conceição, Porto Alegre, Brazil., Lima IPF; CRIO-Centro Regional Integrado de Oncologia, Fortaleza, Brazil., Hughes BGM; Royal Brisbane and Women's Hospital and University of Queensland, Brisbane, QLD, Australia., Pointreau Y; Centre Jean Bernard, Institut Inter-Régional de Cancérologie, Centre de Cancérologie de la Sarthe, Le Mans, France., Aksoy S; Hacettepe University Cancer Institute, Ankara, Turkey., Laban S; Department of Otorhinology and Head and Neck Surgery, Ulm University Medical Center and Comprehensive Cancer Center Ulm, Ulm, Germany., Greil R; Paracelsus Medical University, Salzburg Cancer Research Institute-CCCIT, Cancer Cluster Salzburg, Salzburg, Austria., Burian M; Krankenhaus der Barmherzigen Schwestern Linz, Linz, Austria., Hetnał M; Andrzej Frycz Modrzewski Krakow University, Amethyst Radiotherapy Centre, Rydygier Hospital, Krakow, Poland., Delord JP; Institut Claudius Regaud, IUCT-Oncopole, Toulouse, France., Mesía R; Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain., Taberna M; Catalan Institute of Oncology, ONCOBELL, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain., Waldron JN; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and University of Toronto, Toronto, ON, Canada., Simon C; CHUV University of Lausanne, Lausanne, Switzerland., Grégoire V; Radiation Oncology Department, Centre Léon Bérard, Lyon, France., Harrington KJ; The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, National Institute of Health Research Biomedical Research Centre, London, UK., Swaby RF; Merck & Co, Rahway, NJ, USA., Zhang Y; Merck & Co, Rahway, NJ, USA., Gumuscu B; Merck & Co, Rahway, NJ, USA., Bidadi B; Merck & Co, Rahway, NJ, USA., Siu LL; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre and University of Toronto, Toronto, ON, Canada.

Publikováno v: The Lancet. Oncology [Lancet Oncol] 2024 May; Vol. 25 (5), pp. 572-587. Date of Electronic Publication: 2024 Mar 29.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

LBA5 Primary results of the phase III KEYNOTE-412 study: Pembrolizumab (pembro) with chemoradiation therapy (CRT) vs placebo plus CRT for locally advanced (LA) head and neck squamous cell carcinoma (HNSCC)

Autor: Machiels, J-P., Tao, Y., Burtness, B., Tahara, M., Rischin, D., Alves, G.V., Lima, I.P.F., Hughes, B.G.M., Pointreau, Y., Aksoy, S., Laban, S., Greil, R., Burian, M., Hetnal, M., Licitra, L.F., Swaby, R., Zhang, Y., Gumuscu, B., Bidadi, B., Siu, L.L.

Publikováno v: In Annals of Oncology September 2022 33 Supplement 7:S1399-S1399

A chain mediation model on COVID-19 symptoms and mental health outcomes in Americans, Asians and Europeans.

Autor: Wang C; Institute of Cognitive Neuroscience, Faculty of Education, Huaibei Normal University, Huaibei, China., Chudzicka-Czupała A; Faculty of Psychology, SWPS University of Social Sciences and Humanities, Katowice, Poland., Tee ML; University of the Philippines Manila, Manila, Philippines., Núñez MIL; Department of Social, Work and Differential Psychology, Faculty of Psychology, Complutense University of Madrid, Somosaguas Campus, Madrid, Spain., Tripp C; Department of Psychology, East Carolina University, Greenville, NC, USA., Fardin MA; Department of Psychology, Zahedan Branch, Islamic Azad University, Zahedan, Iran., Habib HA; Institute of Clinical Psychology, University of Karachi, Karachi, Pakistan., Tran BX; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, 100000, Vietnam.; Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 21205, USA., Adamus K; Faculty of Psychology, SWPS University of Social Sciences and Humanities, Katowice, Poland., Anlacan J; University of the Philippines Manila, Manila, Philippines., García MEA; Department of Social, Work and Differential Psychology, Faculty of Psychology, Complutense University of Madrid, Somosaguas Campus, Madrid, Spain., Grabowski D; Faculty of Psychology, SWPS University of Social Sciences and Humanities, Katowice, Poland., Hussain S; DHQ Hospital Jhelum, Jhelum, Pakistan., Hoang MT; Institute for Global Health Innovations, Duy Tan University, Da Nang, Vietnam., Hetnał M; Faculty of Psychology, SWPS University of Social Sciences and Humanities, Katowice, Poland., Le XT; Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Ma W; Institute of Cognitive Neuroscience, Faculty of Education, Huaibei Normal University, Huaibei, China., Pham HQ; Faculty of Medicine, Duy Tan University, Da Nang, Vietnam., Reyes PWC; University of the Philippines Manila, Manila, Philippines., Shirazi M; Department of Psychology, University of Sistan and Baluchestan, Zahedan, Iran., Tan Y; Institute of Cognitive Neuroscience, Faculty of Education, Huaibei Normal University, Huaibei, China., Tee CA; University of the Philippines Manila, Manila, Philippines., Xu L; Institute of Cognitive Neuroscience, Faculty of Education, Huaibei Normal University, Huaibei, China., Xu Z; Institute of Cognitive Neuroscience, Faculty of Education, Huaibei Normal University, Huaibei, China., Vu GT; Center of Excellence in Evidence-Based Medicine, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam., Zhou D; Institute of Cognitive Neuroscience, Faculty of Education, Huaibei Normal University, Huaibei, China., Chan NA; Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK., Kuruchittham V; Southeast Asia One Health University Network (SEAOHUN), Chiang Mai, Thailand., McIntyre RS; Mood Disorders Psychopharmacology Unit, University Health Network, University of Toronto, Toronto, Canada., Ho CSH; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ho R; Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. pcmrhcm@nus.edu.sg.; Institute of Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore, Singapore. pcmrhcm@nus.edu.sg., Sears SF; Department of Psychology, East Carolina University, Greenville, NC, USA.

Publikováno v: Scientific reports [Sci Rep] 2021 Mar 19; Vol. 11 (1), pp. 6481. Date of Electronic Publication: 2021 Mar 19.

Risk Perception of Coronavirus Disease 2019 and Subjective Well-Being Among University Students in China During Quarantine: The Moderating Function of Perceived Social Support.

Autor: Ding, Yadong¹ (AUTHOR), Li, Jing¹ (AUTHOR) jli@cumt.edu.cn

Publikováno v: SAGE Open. Jul-Sep2024, Vol. 14 Issue 3, p1-13. 13p.