Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Heth R. Turnquist"'
Autor:
Virginia Camacho, Victoria R. Matkins, Sweta B. Patel, Jeremie M. Lever, Zhengqin Yang, Li Ying, Ashley E. Landuyt, Emma C. Dean, James F. George, Henry Yang, Paul Brent Ferrell, Craig L. Maynard, Casey T. Weaver, Heth R. Turnquist, Robert S. Welner
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
The nonimmune roles of Tregs have been described in various tissues, including the BM. In this study, we comprehensively phenotyped marrow Tregs, elucidating their key features and tissue-specific functions. We show that marrow Tregs are migratory an
Externí odkaz:
https://doaj.org/article/1f60283a5d9849e4826f16038c6c5f98
Autor:
Madeline Cramer, Catalina Pineda Molina, George Hussey, Heth R. Turnquist, Stephen F. Badylak
Publikováno v:
Tissue Engineering Part A. 28:867-878
The innate immune response, particularly the phenotype of responding macrophages, has significant clinical implications in the remodeling outcome following implantation of biomaterials and engineered tissues. In general, facilitation of an anti-infla
Autor:
Raphael J. Crum, Brydie R. Huckestien, Gaelen Dwyer, Lisa Mathews, David G. Nascari, George S. Hussey, Heth R. Turnquist, John F. Alcorn, Stephen F. Badylak
Publikováno v:
Science Advances. 9
Cytokine storm describes a life-threatening, systemic inflammatory syndrome characterized by elevated levels of proinflammatory cytokines and immune cell hyperactivation associated with multi-organ dysfunction. Matrix-bound nanovesicles (MBV) are a s
Publikováno v:
Adv Drug Deliv Rev
Cardiovascular disease is the leading cause of death around the world, in which myocardial infarction (MI) is a precipitating event. However, current therapies do not adequately address the multiple dysregulated systems following MI. Consequently, re
Autor:
Jing Xu, Jesse Guardado, Rosemary Hoffman, Hui Xu, Rami Namas, Yoram Vodovotz, Li Xu, Mostafa Ramadan, Joshua Brown, Heth R Turnquist, Timothy R Billiar
Publikováno v:
PLoS Medicine, Vol 14, Iss 7, p e1002365 (2017)
BACKGROUND:The immunosuppression and immune dysregulation that follows severe injury includes type 2 immune responses manifested by elevations in interleukin (IL) 4, IL5, and IL13 early after injury. We hypothesized that IL33, an alarmin released ear
Externí odkaz:
https://doaj.org/article/d6af9c6390da4978a694e647077cadec
Autor:
Jing Chang, Yuefeng Xia, Karla Wasserloos, Meihong Deng, Kory J Blose, David A Vorp, Heth R Turnquist, Timothy R Billiar, Bruce A Pitt, Ma-Zhong Zhang, Li-Ming Zhang
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184770 (2017)
Interleukin 33 (IL-33), an inflammatory and mechanically responsive cytokine, is an important component of a TLR4-dependent innate immune process in mucosal epithelium. Although TLR4 also plays a role in sensing biomechanical stretch, a pathway of st
Externí odkaz:
https://doaj.org/article/ee713999558f46b38ed7e096cd03e223
Autor:
Yalcin Kulahci, Liwei Dong, Wensheng Zhang, Heth R. Turnquist, Jignesh V. Unadkat, Chiaki Komatsu, Steven R. Little, Ali Mubin Aral, Abhinav P. Acharya, Riccardo Schweizer, Mario G. Solari, Jonas T. Schnider, James D. Fisher, Vijay S. Gorantla, Angus W. Thomson, Stephen C. Balmert, Vasil E. Erbas
Publikováno v:
Proc Natl Acad Sci U S A
For individuals who sustain devastating composite tissue loss, vascularized composite allotransplantation (VCA; e.g., hand and face transplantation) has the potential to restore appearance and function of the damaged tissues. As with solid organ tran
Autor:
Tengfang Li, Khodor I. Abou-Daya, Sebastien Gingras, Hiromi Kubagawa, Peter Nickerson, Matthew L. Nicotra, Wenhao Chen, Jayne S. Danska, Peixiang Lan, Eiji Takayama, Chris Wiebe, Lisa R. Mathews, Steven M. Mortin-Toth, Jianjiao Chen, Heth R. Turnquist, Wentao Liu, Hehua Dai, Wei Chen, Daqiang Zhao, Amanda L. Williams, Andrew J. Friday, Tao Sun, Martin H. Oberbarnscheidt, Fadi G. Lakkis, Xian Chang Li, Mark J. Shlomchik
Publikováno v:
Frontiers in Immunology
Science
Science
Innate immune cells remember Immunological memory is a phenomenon by which immune cells can quickly recognize an antigen that the host has previously encountered. Certain cells of the innate immune system exhibit memory-like responses know as trained
Publikováno v:
Transplantation. 106:S487-S487
Autor:
Zhenzhen Shao, Zhuang Yu, Bruce R. Pitt, Zhixia Chen, Li-Ming Zhang, Xibing Ding, Heth R. Turnquist, Yao Tong, Li Xu, Timothy R. Billiar, Quan Li, Shuqing Jin
Publikováno v:
Shock. 52:e1-e11
Mechanical ventilation (MV) is frequently employed to manage respiratory failure in sepsis patients and is required for the surgical management of intra-abdominal sepsis. The impact of MV varies dramatically depending on tidal volume, with even moder