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pro vyhledávání: '"Heterologous host"'
Akademický článek
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Publikováno v:
Synthetic and Systems Biotechnology, Vol 6, Iss 1, Pp 1-11 (2021)
Natural products have had a major impact upon quality of life, with antibiotics as a classic example of having a transformative impact upon human health. In this contribution, we will highlight both historic and emerging methods of natural product bi
Externí odkaz:
https://doaj.org/article/46f9a99cf18a4678a7b8445188cbaa9e
Autor:
Yousra Ahmed, Yuriy Rebets, Marta Rodríguez Estévez, Josef Zapp, Maksym Myronovskyi, Andriy Luzhetskyy
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Heterologous expression of secondary metabolite gene clusters is used to achieve increased production of desired compounds, activate cryptic gene clusters, manipulate clusters from genetically unamenable strains, obtain natural pr
Externí odkaz:
https://doaj.org/article/1c123e65dc6e4a108024937001eafa56
Autor:
Ramona Grützner, Ramona Schubert, Claudia Horn, Changqing Yang, Thomas Vogt, Sylvestre Marillonnet
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Betalains are pigments found in plants of the Caryophyllales order, and include the red-purple betacyanins and the yellow-orange betaxanthins. The red pigment from red beets, betanin, is made from tyrosine by a biosynthetic pathway that consists of a
Externí odkaz:
https://doaj.org/article/bbf5cbd9ca1c4b42820f620e6f62511e
Akademický článek
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Publikováno v:
Plants, Vol 10, Iss 7, p 1307 (2021)
Phytocannabinoids are a structurally diverse class of bioactive naturally occurring compounds found in angiosperms, fungi, and liverworts and produced in several plant organs such as the flower and glandular trichrome of Cannabis sativa, the scales i
Externí odkaz:
https://doaj.org/article/c1d86e729b0a4688bf5da1f71baf331f
Publikováno v:
Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology, Vol 6, Iss 1, Pp 1-11 (2021)
Synthetic and Systems Biotechnology, Vol 6, Iss 1, Pp 1-11 (2021)
Natural products have had a major impact upon quality of life, with antibiotics as a classic example of having a transformative impact upon human health. In this contribution, we will highlight both historic and emerging methods of natural product bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139363db35fd231d86e42ec1eb36a8a8
https://doi.org/10.1016/j.synbio.2020.12.001
https://doi.org/10.1016/j.synbio.2020.12.001
Autor:
Zver, Špela
Bakterije iz rodu Streptomyces so proizvajalci medicinsko in industrijsko pomembnih sekundarnih metabolitov. Genom streptomicet zapisuje biosintezne genske gruče (BGG) za več kot 20 različnih sekundarnih metabolitov, vendar večino teh metabolitov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3505::296f5309dc19fe1eff87dfcf37a21d2d
https://repozitorij.uni-lj.si/Dokument.php?id=155509&dn=
https://repozitorij.uni-lj.si/Dokument.php?id=155509&dn=
Autor:
Katherine Williams, Trong Tuan Dao, Colin M. Lazarus, Christine L. Willis, Kate M. J. de Mattos-Shipley, Andy M. Bailey, Marija K Zacharova, Ian M. Prosser
Publikováno v:
Dao, T T, De Mattos-Shipley, K M, Prosser, I M, Williams, K, Zacharova, M K, Lazarus, C M, Willis, C L & Bailey, A M 2021, ' Cleaning the Cellular Factory : Deletion of McrA in Aspergillus oryzae NSAR1 and the generation of a novel kojic acid deficient strain for cleaner heterologous production of secondary metabolites ', Frontiers in Fungal Biology, vol. 2, no. 632542 . https://doi.org/10.3389/ffunb.2021.632542
The use of filamentous fungi as cellular factories, where natural product pathways can be refactored and expressed in a host strain, continues to aid the field of natural product discovery. Much work has been done to develop host strains which are ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d285edc027df24b10cb4da54588a90c3
https://doi.org/10.3389/ffunb.2021.632542
https://doi.org/10.3389/ffunb.2021.632542
Autor:
Li Changxing, Faiz-ul Hassan, Daidong Fang, Zubia Rashid, Muhammad Naveed, Saddia Galani, Afsheen Arif, Asma Ashraf, Li Jianhua, Arif Ali Chishti, Wang Qi, Muhammad Saeed
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 132, Iss, Pp 110918-(2020)
The plant kingdom is a rich source of bioactive compounds, many of which have been used since pre-history for their therapeutic properties to treat a range of illnesses. These metabolites have recently attracted attention to their antineoplastic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391bcbc30d7d1fba252d6ecb91747e5f
http://www.sciencedirect.com/science/article/pii/S0753332220311100
http://www.sciencedirect.com/science/article/pii/S0753332220311100