Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Heterocomplexes"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Infiltrating immune cells are a key component of the tumor microenvironment and play central roles in dictating tumor fate, either promoting anti-tumor immune responses, or sustaining tumor growth, angiogenesis and metastasis. A distinctive microenvi
Externí odkaz:
https://doaj.org/article/46da4250fb814b6290fc200ba6c937da
Autor:
Simona Daniele, Daniela Frosini, Deborah Pietrobono, Lucia Petrozzi, Annalisa Lo Gerfo, Filippo Baldacci, Jonathan Fusi, Chiara Giacomelli, Gabriele Siciliano, Maria Letizia Trincavelli, Ferdinando Franzoni, Roberto Ceravolo, Claudia Martini, Ubaldo Bonuccelli
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Neurodegenerative disorders (NDs) are characterized by abnormal accumulation/misfolding of specific proteins, primarily α-synuclein (α-syn), β-amyloid1–42 (Aβ1–42) and tau, in both brain and peripheral tissues. In addition to oligomers, the r
Externí odkaz:
https://doaj.org/article/b2216fc8bfcd4159826db0d3fe13f4da
Autor:
Simona Daniele, Deborah Pietrobono, Jonathan Fusi, Annalisa Lo Gerfo, Eugenio Cerri, Lucia Chico, Caterina Iofrida, Lucia Petrozzi, Filippo Baldacci, Chiara Giacomelli, Fabio Galetta, Gabriele Siciliano, Ubaldo Bonuccelli, Maria L. Trincavelli, Ferdinando Franzoni, Claudia Martini
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
The loss of protein homeostasis that has been associated with aging leads to altered levels and conformational instability of proteins, which tend to form toxic aggregates. In particular, brain aging presents characteristic patterns of misfolded olig
Externí odkaz:
https://doaj.org/article/d052b85dbbf54be094d387502644bb7a
Akademický článek
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Autor:
Jing Li, Johannes Buchner
Publikováno v:
Biomedical Journal, Vol 36, Iss 3, Pp 106-117 (2013)
Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone which is essential in eukaryotes. It is required for the activation and stabilization of a wide variety of client proteins and many of them are involved in important cellular pathw
Externí odkaz:
https://doaj.org/article/a3d7e158c37446e7b56a94e9c66961e6
Autor:
Lucia Chico, Ubaldo Bonuccelli, Claudia Martini, Simona Daniele, Ferdinando Franzoni, Maria Letizia Trincavelli, Caterina Iofrida, Chiara Giacomelli, Jonathan Fusi, Annalisa Lo Gerfo, Deborah Pietrobono, Fabio Galetta, Eugenio Cerri, Lucia Petrozzi, Gabriele Siciliano, Filippo Baldacci
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
The loss of protein homeostasis that has been associated with aging leads to altered levels and conformational instability of proteins, which tend to form toxic aggregates. In particular, brain aging presents characteristic patterns of misfolded olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382e248685b78a4267988032ada195ec
http://journal.frontiersin.org/article/10.3389/fnagi.2018.00017/full
http://journal.frontiersin.org/article/10.3389/fnagi.2018.00017/full
Publikováno v:
Frontiers in Immunology
Infiltrating immune cells are a key component of the tumor microenvironment and play central roles in dictating tumor fate, either promoting anti-tumor immune responses, or sustaining tumor growth, angiogenesis and metastasis. A distinctive microenvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e3fa52a1d53782dc992684c1738b10b3
http://doc.rero.ch/record/326631/files/DAgostino_FI_2018.pdf
http://doc.rero.ch/record/326631/files/DAgostino_FI_2018.pdf
Septinas são proteínas que ligam GTP e interagem entre si formando heterocomplexos, os quais se organizam em filamentos e estruturas de maior nível de organização. Em humanos são encontrados 13 genes que codificam septinas, as quais se dividem
Autor:
Roberto Ceravolo, Ubaldo Bonuccelli, Maria Letizia Trincavelli, Linda Giampietri, Lucia Petrozzi, Paolo Libertini, Annalisa Lo Gerfo, Daniela Frosini, Filippo Sean Giorgi, Filippo Baldacci, Gloria Tognoni, Valentina Nicoletti, Claudia Martini, Deborah Pietrobono, Laura Betti, Simona Daniele, Rebecca Piccarducci, Elena Donadio, Gabriele Siciliano
A plethora of complex misfolded protein combinations have been found in Alzheimer disease (AD) brains besides the classical pathological hallmarks. Recently, α-synuclein (α-syn) and its heterocomplexes with amyloid-β (Aβ) and tau have been sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa2481aca2a130a4ba53bc0ae358365
http://hdl.handle.net/11568/977967
http://hdl.handle.net/11568/977967
Autor:
Ubaldo Bonuccelli, Deborah Pietrobono, Chiara Giacomelli, Maria Letizia Trincavelli, Jonathan Fusi, Gabriele Siciliano, Simona Daniele, Lucia Petrozzi, Claudia Martini, Filippo Baldacci, Annalisa Lo Gerfo, Roberto Ceravolo, Ferdinando Franzoni, Daniela Frosini
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Neurodegenerative disorders (NDs) are characterized by abnormal accumulation/misfolding of specific proteins, primarily α-synuclein (α-syn), β-amyloid1-42 (Aβ1-42) and tau, in both brain and peripheral tissues. In addition to oligomers, the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f596bfe12ffaa3d15f0cbcbc5a807c19
http://journal.frontiersin.org/article/10.3389/fnmol.2018.00053/full
http://journal.frontiersin.org/article/10.3389/fnmol.2018.00053/full