Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Heterochromatin maintenance"'
Autor:
Abdulla, Amith Zafal
Publikováno v:
Biophysics. Ecole normale supérieure de lyon-ENS LYON, 2022. English. ⟨NNT : 2022ENSL0044⟩
A multitude of stable and heritable phenotypes arise from the same DNA sequence, owing to epigenetic regulatory mechanisms relying on the molecular cooperativity of ``reader-writer'' histone modifying enzymes. We introduce a unified modeling framewor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3393::72d01f2b60cba8d9507af1146206f4c5
https://theses.hal.science/tel-03968006/file/ABDULLA_A_Z_2022ENSL0044_These.pdf
https://theses.hal.science/tel-03968006/file/ABDULLA_A_Z_2022ENSL0044_These.pdf
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-17 (2020)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
BackgrounddADD1 and dXNP proteins are the orthologs inDrosophila melanogasterof the ADD and SNF2 domains, respectively, of the ATRX vertebrate’s chromatin remodeler, they suppress position effect variegation phenotypes and participate in heterochro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a3323d2cbc0acd74e0fca92a5de3b3
http://link.springer.com/article/10.1186/s12860-020-00257-2
http://link.springer.com/article/10.1186/s12860-020-00257-2
Publikováno v:
Proc Natl Acad Sci U S A
In plants and mammals, DNA methylation plays a critical role in transcriptional silencing by delineating heterochromatin from transcriptionally active euchromatin. A homeostatic balance between heterochromatin and euchromatin is essential to genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbbe74e7ca2c456ff2d039ab9923419
https://doi.org/10.1073/pnas.1918172117
https://doi.org/10.1073/pnas.1918172117
Publikováno v:
Journal of Cell Science. 135
Male germ cells establish a unique heterochromatin domain, the XY-body, early in meiosis. How this domain is maintained through the end of meiosis and into post-meiotic germ cell differentiation is poorly understood. ADAD2 is a late meiotic male germ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c8c2a8bd2dce51728f3a19b587c4a3
https://doi.org/10.1242/jcs.259196
https://doi.org/10.1242/jcs.259196
Autor:
Polly Huang, Thomas A. Rando, Albin Huang, Alexander Lieu, Michelle Mao, Qiang Gan, Mingyu Chung, Kevin Yu, Cristina Rodriguez-Mateo, Ling Liu, Gregory W. Charville, Sharon Yang
Publikováno v:
Proc Natl Acad Sci U S A
Skeletal muscle possesses remarkable regenerative ability because of the resident muscle stem cells (MuSCs). A prominent feature of quiescent MuSCs is a high content of heterochromatin. However, little is known about the mechanisms by which heterochr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b4dfe20f6a184ad7845330ff015139
https://doi.org/10.1073/pnas.2025281118
https://doi.org/10.1073/pnas.2025281118
TRIM28 inhibits alternative lengthening of telomere phenotypes by protecting SETDB1 from degradation
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-13 (2021)
Cell & Bioscience
Cell & Bioscience
Background About 10–15% of tumor cells extend telomeres through the alternative lengthening of telomeres (ALT) mechanism, which is a recombination-dependent replication pathway. It is generally believed that ALT cells are related to the chromatin m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c994b0570a679f6a107dd63ad658f255
https://doi.org/10.1186/s13578-021-00660-y
https://doi.org/10.1186/s13578-021-00660-y
Autor:
Vendula Novosadova, Jan Prochazka, Veronika Gresakova, Radislav Sedlacek, Michaela Prochazkova
Publikováno v:
Experimental cell research. 406(2)
Maintenance of genome stability is essential for every living cell as genetic information is repeatedly challenged during DNA replication in each cell division event. Errors, defects, delays, and mistakes that arise during mitosis or meiosis lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295812bc3fb2907e874ac6a2ed0bf112
https://pubmed.ncbi.nlm.nih.gov/34216590
https://pubmed.ncbi.nlm.nih.gov/34216590
Autor:
Benedito Pereira, Antonio M. Lerario, Suely Kazue Nagahashi Marie, Sueli Mieko Oba-Shinjo, Paula R. Sola, Stella G. Cavalcante
Publikováno v:
Clinical neurology and neurosurgery. 210
ATRX-DAXX-H3.3 chromatin remodeler complex is a well known epigenetic factor responsible for the heterochromatin maintenance and control. ATRX is an important nucleosome controller, especially in tandem repeat regions, and DAXX is a multi-function pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee52ff2bdd8aca16fbaf0206a8f441be
https://pubmed.ncbi.nlm.nih.gov/34624827
https://pubmed.ncbi.nlm.nih.gov/34624827
Autor:
Antoine Canat, Adeline Veillet, Renaud Batrin, Clara Dubourg, Robert Illingworth, Emmanuelle Fabre, Pierre Therizols
Genomes comprise a large fraction of repetitive sequences folded into constitutive heterochromatin to protect genome integrity and cell identity.De novoformation of heterochromatin during preimplantation development is an essential step for preservin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::615d561a368c4b87a88f344c7b1e45fe
https://doi.org/10.1101/2021.04.28.441827
https://doi.org/10.1101/2021.04.28.441827
The Arabidopsis F-box protein FBW2 degrades AGO1 to avoid spurious loading of illegitimate small RNA
Autor:
Brun D, Pérez-Salamó I, Blake C. Meyers, Marion Clavel, Nathalie Bouteiller, Hervé Vaucheret, Patricia Baldrich, Hacquard T, Benoît Derrien, Marieke Dubois, Mikhail Schepetilnikov, Lauriane Kuhn, Pascal Genschik, Esther Lechner, Philippe Hammann
RNA silencing is a conserved mechanism in eukaryotes and is involved in development, heterochromatin maintenance and defense against viruses. In plants, ARGONAUTE1 (AGO1) protein plays a central role in both microRNA (miRNA) and small interfering RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce36c62a26de7eee073ec734173eadb5
https://doi.org/10.1101/2021.03.24.436811
https://doi.org/10.1101/2021.03.24.436811