Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hetal V. Shah"'
Autor:
Sonya B Dumanis, Kristen Ratan, Souad McIntosh, Hetal V Shah, Matt Lewis, Timothy H Vines, Randy Schekman, Ekemini A Riley
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011626 (2023)
Externí odkaz:
https://doaj.org/article/b2580ab34e274be5a64bb4e9844b5b58
Autor:
Kristen Ratan, Souad McIntosh, Hetal V. Shah, Matt Lewis, Sonya B. Dumanis, Timothy H. Vines, Randy Schekman, Ekemini A Riley
This is a critical moment in the open science landscape. Over the past few years there has been growing momentum to improve open research policies and require grantees to share all research outputs, from datasets to code to protocols, inFAIR (findabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cebbbb4576b08d75c3f321a345f8537b
https://doi.org/10.1101/2023.02.27.530238
https://doi.org/10.1101/2023.02.27.530238
Autor:
Shireen A. Sarraf, Michael E. Ward, Lynne A. Holtzclaw, Richard J. Youle, Hetal V. Shah, Gil Kanfer, Alicia M. Pickrell
Publikováno v:
Mol Cell
Summary Protein aggregates disrupt cellular homeostasis, causing toxicity linked to neurodegeneration. Selective autophagic elimination of aggregates is critical to protein quality control, but how aggregates are selectively targeted for degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9639dca7754c89b981679202a32049f6
https://europepmc.org/articles/PMC7771836/
https://europepmc.org/articles/PMC7771836/
Publikováno v:
Interventional pulmonology.
Autor:
Dragan Maric, Gil Kanfer, William A. Prinz, Hetal V. Shah, Eric H. Baehrecke, Heather Baldwin, Richard J. Youle, Chunxin Wang, Norbert Brüggemann, Allyson L. Anding, Antonio Velayos-Baeza, Marija Dulovic-Mahlow
Publikováno v:
The Journal of Cell Biology
The VPS13 proteins (VPS13A–D) are thought to mediate lipid transport between organelles and are linked to distinct neurological disorders in humans. Baldwin et al. found that, in addition to known involvement in mitochondrial morphology, VPS13D is
Misfolded protein aggregates can disrupt cellular homeostasis and cause toxicity, a hallmark of numerous neurodegenerative diseases. Protein quality control by the ubiquitin proteasome system (UPS) and autophagy is vital for clearance of aggregates a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d52d8c48eeaa0a95b1c7422b660768
https://doi.org/10.1101/558767
https://doi.org/10.1101/558767