Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hetal B Patel"'
Publikováno v:
Frontiers in Immunology, Vol 2 (2011)
Macrophages have crucial functions in initiating the inflammatory reaction in a strict temporal and spatial manner to provide a ‘clear-up’ response required for resolution. Hormonal peptides such as melanocortins modulate macrophage reactivity an
Externí odkaz:
https://doaj.org/article/60b61a6ca8f041e296f7e020a426e2d3
Autor:
Tulsi J. Dalwadi, Tanvi N. Parmar, Hetal B. Patel, Shilpa Ashok Jani, Sagar K. Parmar, Yesha M. Parekh
Publikováno v:
International Journal of Current Microbiology and Applied Sciences. 5:767-787
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbad3d098062d0a70d35641a699809d2
https://doi.org/10.20546/ijcmas.2016.505.078
https://doi.org/10.20546/ijcmas.2016.505.078
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9a0e6ce7f675e8e12315c1a74e5e94
https://doi.org/10.1096/fasebj.2018.32.1_supplement.675.7
https://doi.org/10.1096/fasebj.2018.32.1_supplement.675.7
Autor:
Hetal B. Patel, Mauro Perretti, Thomas E. N. Jonassen, Trinidad Montero-Melendez, Søren Nielsen, Michael Seed
Publikováno v:
The American Journal of Pathology. 179:259-269
Synthetic and natural melanocortin (MC) peptides afford inhibitory properties in inflammation and tissue injury, but characterization of receptor involvement is still elusive. We used the agonist AP214 to test MC-dependent anti-inflammatory effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567502208459e3c6730b84dd1652e263
https://doi.org/10.1016/j.ajpath.2011.03.042
https://doi.org/10.1016/j.ajpath.2011.03.042
Publikováno v:
Current Rheumatology Reports. 13:138-145
Gouty arthritis is a form of acute joint inflammation provoked by joint deposition of urate crystals. Although this acute pathology resolves after a few days, the marked degree of inflammation in the joint and--possibly more important to the patient-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc78f0543c748626741d491f37dd076
https://doi.org/10.1007/s11926-011-0163-0
https://doi.org/10.1007/s11926-011-0163-0
Autor:
Mohini Gray, Costantino Pitzalis, André L. F. Sampaio, Mauro Perretti, Paolo Grieco, Stephen J. Getting, Fulvio D'Acquisto, Michele Bombardieri, Hetal B. Patel
Publikováno v:
The FASEB Journal. 24:4835-4843
The development of biological therapies has improved management of rheumatoid arthritis. However, costs and unresponsiveness to therapy in a sizeable proportion of patients limit their use, making it imperative to identify new targets for drug develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ea2dae7419e4f1cd78b0ed2c8881e7
https://doi.org/10.1096/fj.10.167759
https://doi.org/10.1096/fj.10.167759
Autor:
Mohini Gray, Robert Hannon, Fulvio D'Acquisto, Julia C. Buckingham, Jesmond Dalli, Vincenzo Brancaleone, Hetal B. Patel, Mauro Perretti, Neil Dufton, Roderick J. Flower
Publikováno v:
The Journal of Immunology. 184:2611-2619
The human formyl-peptide receptor (FPR)-2 is a G protein-coupled receptor that transduces signals from lipoxin A4, annexin A1, and serum amyloid A (SAA) to regulate inflammation. In this study, we report the creation of a novel mouse colony in which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751da6b7e0cfec9aa3ca998afe0439dc
https://doi.org/10.4049/jimmunol.0903526
https://doi.org/10.4049/jimmunol.0903526
Autor:
Ian J. Jackson, Donald J. Davidson, Mauro Perretti, Sheila Webb, Fiona Semple, Mohini Gray, Hsin-Ni Li, Julia R. Dorin, Hetal B. Patel
Publikováno v:
European Journal of Immunology. 40:1073-1078
Beta-defensins are antimicrobial peptides with an essential role in the innate immune response. In addition beta-defensins can also chemoattract cells involved in adaptive immunity. Until now, based on evidence from dendritic cell stimulation, human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86e6aedc11a121a9f733e74feb13faef
https://doi.org/10.1002/eji.200940041
https://doi.org/10.1002/eji.200940041
Autor:
Mark J.P. Kerrigan, Derek Renshaw, Y. Bhadresa, Magdalena Kaneva, Hetal B. Patel, Giovanna Leoni, Stephen J. Getting, Ian C. Locke
Publikováno v:
The Scientific World Journal
The Scientific World Journal, Vol 9, Pp 1394-1414 (2009)
The Scientific World Journal, Vol 9, Pp 1394-1414 (2009)
Arthritic pathologies are a major cause of morbidity within the western world, with rheumatoid arthritis affecting approximately 1% of adults. This review highlights the therapeutic potential of naturally occurring hormones and their peptides, in bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e826e4af80ca2bdf85d9404d4ea12c
http://europepmc.org/articles/PMC5823194
http://europepmc.org/articles/PMC5823194
Autor:
Hetal B. Patel, Paolo Grieco, Joanne F. Murray, Giovanna Leoni, Mauro Perretti, Stephen J. Getting, André L. F. Sampaio, Felicity N. E. Gavins
Publikováno v:
The FASEB Journal
The existence of anti-inflammatory circuits centered on melanocortin receptors (MCRs) has been supported by the inhibitory properties displayed by melanocortin peptides in models of inflammation and tissue injury. Here we addressed the pathophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f19c6064e01f118da51b6add92eabd
https://doi.org/10.1096/fj.08-113886
https://doi.org/10.1096/fj.08-113886