Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Hestia Mellert"'
Autor:
Audrey Audetat, Chérie Tschida, Sarah Kreston, Adam Stephen, Brittany D’Alessio, Madeline Bondy, Leisa Jackson, Hestia Mellert, Niki Givens, Ubaradka G. Sathyanarayana, Gary A. Pestano
Publikováno v:
Diagnostics, Vol 12, Iss 3, p 729 (2022)
Liquid biopsies are an integral part of the diagnosis of cancer. Here, we have extended previous validation studies of a new targeted NGS panel to include the detection of copy number amplifications (CNAs), fusions, and exon skipping variants. Detect
Externí odkaz:
https://doaj.org/article/cc965d9bf42b4d178be891be87e839f8
Autor:
Hestia Mellert, Jordan Reese, Leisa Jackson, Victoria Maxwell, Chérie Tschida, Gary A. Pestano
Publikováno v:
Diagnostics, Vol 11, Iss 2, p 155 (2021)
Liquid biopsy tests have become an integral part of the molecular diagnosis of patients with non-small cell lung cancer (NSCLC). We describe a new test panel that uses very low input (20 ng) of cell-free nucleic acids extracted from human plasma, whi
Externí odkaz:
https://doaj.org/article/87c50d5d684247908d933632be9a9a19
Publikováno v:
Diagnostics, Vol 10, Iss 12, p 1032 (2020)
A major hurdle for blood-based proteomic diagnostics is efficient transport of specimens from the collection site to the testing laboratory. Dried blood spots have shown utility for diagnostic applications, specifically those where red blood cell hem
Externí odkaz:
https://doaj.org/article/b09254735e6f424e8839f3f735924be9
Autor:
Jessica A. Monteith, Hestia Mellert, Morgan A. Sammons, Laudita A. Kuswanto, Stephen M. Sykes, Lois Resnick-Silverman, James J. Manfredi, Shelley L. Berger, Steven B. McMahon
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1207-1220 (2016)
The p53 tumor suppressor gene encodes a sequence‐specific transcription factor. Mutations in the coding sequence of p53 occur frequently in human cancer and often result in single amino acid substitutions (missense mutations) in the DNA binding dom
Externí odkaz:
https://doaj.org/article/c5baaa74142c491f88e3fa18ba1e495f
Autor:
Hestia Mellert, Joaquín M. Espinosa
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1335-1336 (2013)
The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Reports, Timofeev et al. (2013) and Valente et al. (2013) reveal context-dependent contributions of p53-dependent apoptosis to its tumor-suppressive functio
Externí odkaz:
https://doaj.org/article/efb5d9e3d4cb4cf1aa104854f4d617b5
Autor:
Robert B. Den, Karen E. Knudsen, Adam P. Dicker, Paolo Fortina, Ruth Birbe, Adam Ertel, Sankar Addya, Hestia Mellert, Steve B. McMahon, Ankur Sharma, Raymond O' Neill, Yi Liu, Steve Ciment, Ettickan Boopathi, Chellappagounder Thangavel
Supplemental Figure 5. RB status is retained in biopsy proven local recurrence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669d941dd0b6cb659a2ca51770357e91
https://doi.org/10.1158/1078-0432.22461255.v1
https://doi.org/10.1158/1078-0432.22461255.v1
Autor:
Robert B. Den, Karen E. Knudsen, Adam P. Dicker, Paolo Fortina, Ruth Birbe, Adam Ertel, Sankar Addya, Hestia Mellert, Steve B. McMahon, Ankur Sharma, Raymond O' Neill, Yi Liu, Steve Ciment, Ettickan Boopathi, Chellappagounder Thangavel
Purpose: Perturbations in the retinoblastoma pathway are over-represented in advanced prostate cancer; retinoblastoma loss promotes bypass of first-line hormone therapy. Conversely, preliminary studies suggested that retinoblastoma-deficient tumors m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6389d89b86332b06cc736d5aa73892c1
https://doi.org/10.1158/1078-0432.c.6524742.v1
https://doi.org/10.1158/1078-0432.c.6524742.v1
Autor:
Robert B. Den, Karen E. Knudsen, Adam P. Dicker, Paolo Fortina, Ruth Birbe, Adam Ertel, Sankar Addya, Hestia Mellert, Steve B. McMahon, Ankur Sharma, Raymond O' Neill, Yi Liu, Steve Ciment, Ettickan Boopathi, Chellappagounder Thangavel
Supplemental Figure 2. RB deficiency promotes enhanced apoptotic pathway in response to ionizing radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd1dc1de5704ee8c45d6f25d6d63955
https://doi.org/10.1158/1078-0432.22461264
https://doi.org/10.1158/1078-0432.22461264
Autor:
Robert B. Den, Karen E. Knudsen, Adam P. Dicker, Paolo Fortina, Ruth Birbe, Adam Ertel, Sankar Addya, Hestia Mellert, Steve B. McMahon, Ankur Sharma, Raymond O' Neill, Yi Liu, Steve Ciment, Ettickan Boopathi, Chellappagounder Thangavel
Supplemental Figure 1. RB status does not impinge on the alterations of cell cycle after radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451889832bee2f409357dd04df90d56a
https://doi.org/10.1158/1078-0432.22461267
https://doi.org/10.1158/1078-0432.22461267
Autor:
Robert B. Den, Karen E. Knudsen, Adam P. Dicker, Paolo Fortina, Ruth Birbe, Adam Ertel, Sankar Addya, Hestia Mellert, Steve B. McMahon, Ankur Sharma, Raymond O' Neill, Yi Liu, Steve Ciment, Ettickan Boopathi, Chellappagounder Thangavel
Supplemental Figure 4. PLK3 expression promotes apoptotic cell death in the setting of RB loss.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf4a122274619d362e80c1535d1fd4f
https://doi.org/10.1158/1078-0432.22461258
https://doi.org/10.1158/1078-0432.22461258