Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hesther de Ruiter"'
Autor:
Bas Molenaar, Louk T. Timmer, Marjolein Droog, Ilaria Perini, Danielle Versteeg, Lieneke Kooijman, Jantine Monshouwer-Kloots, Hesther de Ruiter, Monika M. Gladka, Eva van Rooij
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Molenaar et al. use scRNA-seq to profile cardiac cell gene expression changes at three time points following ischemic injury. They observe that B2M is secreted by cardiomyocytes following injury, promoting scar formation. This data may be useful in f
Externí odkaz:
https://doaj.org/article/4ad3dd3f14f6498bac1a498a6c119c9c
Autor:
Christoph Göbl, Vanessa K. Morris, Loes van Dam, Marieke Visscher, Paulien E. Polderman, Christoph Hartlmüller, Hesther de Ruiter, Manuel Hora, Laura Liesinger, Ruth Birner-Gruenberger, Harmjan R. Vos, Bernd Reif, Tobias Madl, Tobias B. Dansen
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
The tumor suppressor p16INK4A induces cell cycle arrest and senescence in response to oncogenic transformation and is therefore frequently lost in cancer. p16INK4A is also known to accumulate under conditions of oxidative stress. Thus, we hypothesize
Externí odkaz:
https://doaj.org/article/455304bdf2544f08bd2e21616c0f6c16
Autor:
Sebastiaan J. van Kampen, Su Ji Han, Willem B. van Ham, Eirini Kyriakopoulou, Elizabeth W. Stouthart, Birgit Goversen, Jantine Monshouwer-Kloots, Ilaria Perini, Hesther de Ruiter, Petra van der Kraak, Aryan Vink, Linda W. van Laake, Judith A. Groeneweg, Teun P. de Boer, Hoyee Tsui, Cornelis J. Boogerd, Toon A.B. van Veen, Eva van Rooij
Publikováno v:
Stem Cell Reports. 18:749-764
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9731983c42617636e28f39b28b5143
https://doi.org/10.1016/j.stemcr.2023.01.015
https://doi.org/10.1016/j.stemcr.2023.01.015
Autor:
Hoyee Tsui, Sebastiaan Johannes van Kampen, Su Ji Han, Viviana Meraviglia, Willem B. van Ham, Simona Casini, Petra van der Kraak, Aryan Vink, Xiaoke Yin, Manuel Mayr, Alexandre Bossu, Gerard A. Marchal, Jantine Monshouwer-Kloots, Joep Eding, Danielle Versteeg, Hesther de Ruiter, Karel Bezstarosti, Judith Groeneweg, Sjoerd J. Klaasen, Linda W. van Laake, Jeroen A.A. Demmers, Geert J.P.L. Kops, Christine L. Mummery, Toon A.B. van Veen, Carol Ann Remme, Milena Bellin, Eva van Rooij
Publikováno v:
Science Translational Medicine, 15(688):eadd4248. American Association for the Advancement of Science
Arrhythmogenic cardiomyopathy (ACM) is an inherited progressive cardiac disease. Many patients with ACM harbor mutations in desmosomal genes, predominantly in plakophilin-2 ( PKP2 ). Although the genetic basis of ACM is well characterized, the underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808e5a3b69efcf55e7b85a6c68336d37
https://pure.eur.nl/en/publications/b9118c51-f369-4627-b2a5-3b2872f8dccd
https://pure.eur.nl/en/publications/b9118c51-f369-4627-b2a5-3b2872f8dccd
Autor:
Cornelis J Boogerd, Grégory P A Lacraz, Ábel Vértesy, Sebastiaan J van Kampen, Ilaria Perini, Hesther de Ruiter, Danielle Versteeg, Andreas Brodehl, Petra van der Kraak, Mauro Giacca, Nicolaas de Jonge, Jan Philipp Junker, Alexander van Oudenaarden, Aryan Vink, Eva van Rooij
Publikováno v:
Cardiovascular Research. Oxford University Press
Aims Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that is characterized by progressive loss of myocardium that is replaced by fibro-fatty cells, arrhythmias, and sudden cardiac death. While myocardial degeneration and fibro-fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb1a73dcfa64ab9ef09d4f03d0a95fb
https://doi.org/10.1093/cvr/cvac072
https://doi.org/10.1093/cvr/cvac072
Autor:
Lieneke Kooijman, Monika M Gladka, Charlotte J Demkes, Hesther de Ruiter, Joep E C Eding, Aryan Vink, Alexander Bossu, Marta Vigil-Garcia, Ilaria Perini, Toon A.B. van Veen, Eva van Rooij, Magdalena Harakalova, Folkert W. Asselbergs, Cornelis J. Boogerd, Danielle Versteeg
Publikováno v:
Cardiovascular research. Oxford University Press
Cardiovascular Research
Cardiovascular Research. Oxford University Press
Cardiovascular Research
Cardiovascular Research. Oxford University Press
Aims Pathological cardiac remodeling is characterized by cardiomyocyte hypertrophy and fibroblast activation, which can ultimately lead to maladaptive hypertrophy and heart failure (HF). Genome-wide expression analysis on heart tissue has been instru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49023405e16c071e6ed3524712ce087e
https://pure.amc.nl/en/publications/gene-expression-profiling-of-hypertrophic-cardiomyocytes-identifies-new-players-in-pathological-remodelling(bc12e8b4-f019-4bdd-bd30-868992114894).html
https://pure.amc.nl/en/publications/gene-expression-profiling-of-hypertrophic-cardiomyocytes-identifies-new-players-in-pathological-remodelling(bc12e8b4-f019-4bdd-bd30-868992114894).html
Autor:
Vanessa K. Morris, Christoph Göbl, Laura Liesinger, Harmjan R. Vos, Tobias B. Dansen, Manuel Hora, Paulien E. Polderman, Bernd Reif, Christoph Hartlmueller, Ruth Birner-Gruenberger, Tobias Madl, Marieke Visscher, Hesther de Ruiter, Loes van Dam
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biol. 28:101316 (2020)
Redox Biology
Redox Biol. 28:101316 (2020)
The tumor suppressor p16INK4A induces cell cycle arrest and senescence in response to oncogenic transformation and is therefore frequently lost in cancer. p16INK4A is also known to accumulate under conditions of oxidative stress. Thus, we hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0c192bc880623b2c14023c5a1b1886
http://www.sciencedirect.com/science/article/pii/S2213231719307918
http://www.sciencedirect.com/science/article/pii/S2213231719307918
Autor:
Charlotte Demkes, Mauro Giacca, Bastiaan Spanjaard, Farhad Akbari Moqadam, Lieneke Kooijman, Hesther de Ruiter, Lorena Zentilin, D Versteeg, Bas Molenaar, Anne Katrine Johansen, Eva van Rooij, Ana Rita Leitoguinho
Publikováno v:
Circulation Research, 121(10), 1168-1181. Lippincott Williams & Wilkins
Rationale: CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated protein 9)–based DNA editing has rapidly evolved as an attractive tool to modify the genome. Although CRISPR/Cas9 has been extensively used to manipulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb66c30d26a595eda1fb2d3c95d584e3
https://doi.org/10.1161/circresaha.116.310370
https://doi.org/10.1161/circresaha.116.310370
Autor:
Folkert W. Asselbergs, J. E. C. Eding, Aryan Vink, Danielle Versteeg, Monika M Gladka, Marta Vigil-Garcia, Alex Bossu, Charlotte Demkes, Eva van Rooij, Magdalena Harakalova, Hesther de Ruiter, Toon A.B. van Veen
Publikováno v:
Circulation Research. 125
Pathological remodeling during cardiac disease is a detrimental response characterized by cardiomyocyte hypertrophy and fibroblast activation, which can ultimately lead to heart failure. Genome wide expression analysis on full heart tissue have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63bc19db88c27d83a1d5fd94b0cd866
https://doi.org/10.1161/res.125.suppl_1.262
https://doi.org/10.1161/res.125.suppl_1.262
Autor:
Eva van Rooij, Jan Philip Junker, Manon M. H. Huibers, Petra van der Kraak, Hesther de Ruiter, Ábel Vértesy, Cornelis J. Boogerd, Aryan Vink, Grègory P.A. Lacraz, Nicolaas de Jonge, Ilaria Perini, Andreas Brodehl
Publikováno v:
Circulation Research. 125
Introduction: Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder characterized by progressive loss of contractile myocardium which is replaced by fibrous and adipose tissue, ventricular arrhythmias, and sudden cardiac death. Fibrofa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::405aa3a74bc68bcf7e7b9b84875f751f
https://doi.org/10.1161/res.125.suppl_1.510
https://doi.org/10.1161/res.125.suppl_1.510