Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hester C. van Wyk"'
Autor:
Colin S. Wood, Kathryn A.F. Pennel, Holly Leslie, Assya Legrini, Andrew J. Cameron, Lydia Melissourgou-Syka, Jean A. Quinn, Hester C. van Wyk, Jennifer Hay, Antonia K. Roseweir, Colin Nixon, Campbell S.D. Roxburgh, Donald C. McMillan, Andrew V. Biankin, Owen J. Sansom, Paul G. Horgan, Joanne Edwards, Colin W. Steele, Nigel B. Jamieson
Publikováno v:
Cancer Research. 83:1329-1344
Strong immune responses in primary colorectal cancer correspond with better patient survival following surgery compared with tumors with predominantly stromal microenvironments. However, biomarkers to identify patients with colorectal cancer liver me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774945f4abcfa2bf86be777d51c0e348
https://doi.org/10.1158/0008-5472.can-22-2794
https://doi.org/10.1158/0008-5472.can-22-2794
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
All supplementary figures and supplementary tables 1 and 2 from the manuscript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403e64c8ec0da6f59bb48f6e55065ecc
https://doi.org/10.1158/0008-5472.22633296.v1
https://doi.org/10.1158/0008-5472.22633296.v1
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
Gene Set Enrichment Analysis results obtained by interrogating ranked list of differentially expressed KM high vs KM low genes against the REACTOME curated gene set database using ClusterProfiler package
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eb2629c57087ccdf7531fa25bf1bf6
https://doi.org/10.1158/0008-5472.22633287.v1
https://doi.org/10.1158/0008-5472.22633287.v1
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
Supplementary details regarding methods and materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c84d91b354ecd603c7bb4d3097c5852
https://doi.org/10.1158/0008-5472.22633293.v1
https://doi.org/10.1158/0008-5472.22633293.v1
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
SpatialDecon derived immune cell counts aggregated by Region, KM grade and KRAS status with pairwise comparison between groups. Mann-Whitney test used to determine statistical significance between groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58adec63ac2802bd346cb81495e87314
https://doi.org/10.1158/0008-5472.22633290
https://doi.org/10.1158/0008-5472.22633290
Autor:
Nigel B. Jamieson, Colin W. Steele, Joanne Edwards, Paul G. Horgan, Owen J. Sansom, Andrew V. Biankin, Donald C. McMillan, Campbell S.D. Roxburgh, Colin Nixon, Antonia K. Roseweir, Jennifer Hay, Hester C. van Wyk, Jean A. Quinn, Lydia Melissourgou-Syka, Andrew J. Cameron, Assya Legrini, Holly Leslie, Kathryn A.F. Pennel, Colin S. Wood
Strong immune responses in primary colorectal cancer correspond with better patient survival following surgery compared with tumors with predominantly stromal microenvironments. However, biomarkers to identify patients with colorectal cancer liver me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0623b1dd2a51eb627cb56e66bac841
https://doi.org/10.1158/0008-5472.c.6599682.v1
https://doi.org/10.1158/0008-5472.c.6599682.v1
Autor:
Colin S Wood, Kathryn AF Pennel, Holly Leslie, Assya Legrini, Andrew J Cameron, Lydia Melissourgou-Syka, Jean A Quinn, Hester C van Wyk, Jennifer Hay, Antonia K Roseweir, Colin Nixon, Campbell SD Roxburgh, Donald C McMillan, Andrew V Biankin, Owen J Sansom, Paul G Horgan, Joanne Edwards, Colin W Steele, Nigel B Jamieson
BackgroundPatients demonstrating strong immune responses to primary colorectal cancer (CRC) have a survival benefit following surgery, while those with predominantly stromal microenvironments do poorly. Biomarkers to identify patients with colorectal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c8fc92f58d773ceeffcae3fb4890683
https://doi.org/10.1101/2022.09.21.508569
https://doi.org/10.1101/2022.09.21.508569
Autor:
Kathryn Af, Pennel, Jean A, Quinn, Colin, Nixon, Jitwadee, Inthagard, Hester C, van Wyk, David, Chang, Selma, Rebus, Jennifer, Hay, Noori N, Maka, Campbell Sd, Roxburgh, Paul G, Horgan, Donald C, McMillan, James H, Park, Antonia K, Roseweir, Colin W, Steele, Joanne, Edwards
Publikováno v:
The journal of pathology. Clinical research. 8(6)
CXCL8 is an inflammatory chemokine elevated in the colorectal cancer (CRC) tumour microenvironment. CXCR2, the major receptor for CXCL8, is predominantly expressed by neutrophils. In the cancer setting, CXCL8 plays important roles in neutrophil chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1aa71863d043e46e2f3e3fedb9d19fdc
https://pubmed.ncbi.nlm.nih.gov/35879507
https://pubmed.ncbi.nlm.nih.gov/35879507
Autor:
Hester C. van Wyk, Phimmada Hatthakarnkul, Amna Ahmed Mohemmd Matly, Aula Ammar, Donald C. McMillan, Joanne Edwards, Jean A. Quinn
Publikováno v:
Critical reviews in oncology/hematology. 167
Introduction:\ud Despite a well-known prognostic role in colorectal cancer, the genomic profiling of tumour budding remains to be elucidated. We aim to review the association of common mutations with tumour budding.\ud \ud Methods:\ud A systematic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cbc8f168c50e90de9eee7eec0dc4ab
https://pubmed.ncbi.nlm.nih.gov/34619332
https://pubmed.ncbi.nlm.nih.gov/34619332
Autor:
Paul G. Horgan, Emilie Combet, James H. Park, Domenic G Di Rollo, Campbell S.D. Roxburgh, Hester C. van Wyk, Cariss Little, Fiona A Ross, David Mansouri, Donald C. McMillan
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and IrelandREFERENCES. 24(2)
Although the relationship between colorectal neoplasia and inflammation is well described, the role of faecal calprotectin (FC) in clinical practice to diagnose or screen patients for colorectal neoplasia is less defined. This prospective study chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5eb45b4f6ed7e3c13239e90fe6ee22e
https://pubmed.ncbi.nlm.nih.gov/34614299
https://pubmed.ncbi.nlm.nih.gov/34614299