Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Hesta V. McNeill"'
Autor:
Kelly Coffey, Timothy J Blackburn, Susan Cook, Bernard T Golding, Roger J Griffin, Ian R Hardcastle, Lorraine Hewitt, Kety Huberman, Hesta V McNeill, David R Newell, Celine Roche, Claudia A Ryan-Munden, Anna Watson, Craig N Robson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45539 (2012)
Tip60 (KAT5) is a histone acetyltransferase (HAT enzyme) involved in multiple cellular processes including transcriptional regulation, DNA damage repair and cell signalling. In prostate cancer, aggressive cases over-express Tip60 which functions as a
Externí odkaz:
https://doaj.org/article/ad0f8a29724847c78bbacae4be080277
Autor:
Frances V. Fuller-Pace, John Lunec, Hesta V. McNeill, David W. Meek, Craig N. Robson, Ian R. Logan, Xiaohong Lu, Susan Cook
Publikováno v:
Nucleic Acids Research
Here we define an important role for heat shock factor 1 (HSF1) in the cellular response to genotoxic agents. We demonstrate for the first time that HSF1 can complex with nuclear p53 and that both proteins are co-operatively recruited to p53-responsi