Differences in Systemic IgA Reactivity and Circulating Th Subsets in Healthy Volunteers With Specific Microbiota Enterotypes

Autor: Christina Grosserichter-Wagener, Djawad Radjabzadeh, Hessel van der Weide, Kyra N. Smit, Robert Kraaij, John P. Hays, Menno C. van Zelm

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Changes in the intestinal microbiota have been associated with the development of immune-mediated diseases in humans. Additionally, the introduction of defined bacterial species into the mouse intestinal microbiota has been shown to impact on the ada

Externí odkaz: https://doaj.org/article/879bea92b03e4432b320ba43a7fad51b

Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia–Septicemia Model in Rats

Autor: Mireille van Westreenen, Hessel van der Weide, Stefan A. Boers, Wil H. F. Goessens, Rixt A. Wijma, John P. Hays, Marian T. ten Kate, Denise M. C. Vermeulen-de Jongh, Aart van der Meijden, Irma A. J. M. Bakker-Woudenberg

Publikováno v: Antibiotics, Vol 9, Iss 3, p 109 (2020)
Antibiotics
Antibiotics-Basel, 9(3):109. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 9
Issue 3

Background: Recent scientific reports on the use of high dose tigecycline monotherapy as a &ldquo
drug of last resort&rdquo
warrant further research into the use of this regimen for the treatment of severe multidrug-resistant, Gram-negative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211670a5771abd2f6ce9de98be482db1
https://www.mdpi.com/2079-6382/9/3/109

Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles

Autor: Irma A. J. M. Bakker-Woudenberg, Wil H. F. Goessens, Alessandro Pini, Denise M. C. Vermeulen-de Jongh, Hessel van der Weide, John P. Hays, Deborah Kreft, Stefan A. Boers, Aart van der Meijden, Marian T. ten Kate, Magnus Strandh, Chiara Falciani

Publikováno v: International Journal of Antimicrobial Agents, 54(2), 159-166. Elsevier

Colistin is an antimicrobial peptide (AMP) used as a drug of last resort, although plasmid-mediated colistin resistance (MCR) has been reported. AA139 and SET-M33 are novel AMPs currently in development for the treatment of multidrug-resistant (MDR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8a5b85943ebf700bf11ffe8279f753
https://pure.eur.nl/en/publications/dcfcb07e-00fd-405d-893c-ce58bbc09d39