Remodeling of skeletal muscle myosin metabolic states in hibernating mammals.

Autor: Lewis CTA; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Melhedegaard EG; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Ognjanovic MM; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Olsen MS; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Laitila J; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Seaborne RAE; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.; Centre for Human and Applied Physiological Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Gronset M; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Zhang C; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, United States., Iwamoto H; Spring-8, Japan Synchrotron Radiation Research Institute, Hyogo, Japan., Hessel AL; Institute of Physiology II, University of Muenster, Muenster, Germany.; Accelerated Muscle Biotechnologies Consultants, Boston, United States., Kuehn MN; Institute of Physiology II, University of Muenster, Muenster, Germany.; Accelerated Muscle Biotechnologies Consultants, Boston, United States., Merino C; Biosfer Teslab, Reus, Spain., Amigo N; Biosfer Teslab, Reus, Spain., Frobert O; Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark.; Faculty of Health, Department of Cardiology, Örebro University, Örebro, Sweden., Giroud S; Energetics Lab, Department of Biology, Northern Michigan University, Marquette, United States.; Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Sciences, University of Veterinary Medicine Vienna, Vienna, Austria., Staples JF; Department of Biology, University of Western Ontario, London, Canada., Goropashnaya AV; Center for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, United States., Fedorov VB; Center for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, United States., Barnes B; Center for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, United States., Toien O; Center for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, United States., Drew K; Center for Transformative Research in Metabolism, Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, United States., Sprenger RJ; Department of Zoology, University of British Columbia, Vancouver, Canada., Ochala J; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: ELife [Elife] 2024 May 16; Vol. 13. Date of Electronic Publication: 2024 May 16.

Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads.

Autor: Hessel AL; Institute of Physiology II, University of Muenster, Muenster, Germany. anthony.hessel@uni-muenster.de.; Accelerated Muscle Biotechnologies Consultants, Boston, MA, USA. anthony.hessel@uni-muenster.de., Engels NM; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA., Kuehn MN; Institute of Physiology II, University of Muenster, Muenster, Germany.; Accelerated Muscle Biotechnologies Consultants, Boston, MA, USA., Nissen D; BioCAT, Department of Biology, Illinois Institute of Technology, Chicago, IL, USA., Sadler RL; Department of Physiology, University of Arizona, Tucson, AZ, USA., Ma W; BioCAT, Department of Biology, Illinois Institute of Technology, Chicago, IL, USA., Irving TC; BioCAT, Department of Biology, Illinois Institute of Technology, Chicago, IL, USA., Linke WA; Institute of Physiology II, University of Muenster, Muenster, Germany., Harris SP; Department of Physiology, University of Arizona, Tucson, AZ, USA. samharris@arizona.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Mar 23; Vol. 15 (1), pp. 2628. Date of Electronic Publication: 2024 Mar 23.

Titin-based force regulates cardiac myofilament structures mediating length-dependent activation.

Autor: Hessel AL; Institute of Physiology II, University of Muenster; Muenster, Germany., Kuehn MN; Institute of Physiology II, University of Muenster; Muenster, Germany., Engels NM; Department of Cellular and Molecular Medicine, University of Arizona; Tucson, AZ, USA., Nissen DL; BioCAT, Department of Biology, Illinois Institute of Technology; Chicago, USA., Freundt JK; Institute of Physiology II, University of Muenster; Muenster, Germany., Ma W; BioCAT, Department of Biology, Illinois Institute of Technology; Chicago, USA., Irving TC; BioCAT, Department of Biology, Illinois Institute of Technology; Chicago, USA., Linke WA; Institute of Physiology II, University of Muenster; Muenster, Germany.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 13. Date of Electronic Publication: 2023 Nov 13.

Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure.

Autor: Hessel AL; Institute of Physiology II, University of Muenster; Muenster, Germany., Kuehn M; Institute of Physiology II, University of Muenster; Muenster, Germany., Han SW; Institute of Physiology II, University of Muenster; Muenster, Germany., Ma W; BioCAT, Department of Biology, Illinois Institute of Technology; Chicago, USA., Irving TC; BioCAT, Department of Biology, Illinois Institute of Technology; Chicago, USA., Momb BA; Department of Kinesiology, University of Massachusetts - Amherst; Amherst, MA, USA., Song T; Center for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA., Sadayappan S; Center for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA., Linke WA; Institute of Physiology II, University of Muenster; Muenster, Germany., Palmer BM; Department of Molecular Physiology and Biophysics, University of Vermont; Burlington, VT, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 23. Date of Electronic Publication: 2023 Oct 23.

Predominant myosin superrelaxed state in canine myocardium with naturally occurring dilated cardiomyopathy.

Autor: Ochala J; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Lewis CTA; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Beck T; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Iwamoto H; SPring-8, Japan Synchrotron Radiation Research Institute, Hyogo, Japan., Hessel AL; Institute of Physiology II, University of Muenster, Muenster, Germany.; Accelerated Muscle Biotechnologies, Boston, Massachusetts, United States., Campbell KS; Department of Physiology, University of Kentucky, Lexington, Kentucky, United States.; Division of Cardiovascular Medicine, University of Kentucky, Lexington, Kentucky, United States., Pyle WG; IMPART Investigator Team, Dalhousie Medicine, Saint John, New Brunswick, Canada.; Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada.

Publikováno v: American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2023 Sep 01; Vol. 325 (3), pp. H585-H591. Date of Electronic Publication: 2023 Jul 28.