Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hessam, Siavash"'
Publikováno v:
Current Cancer Drug Targets. 4:637-651
Head and neck cancer, the sixth most common type of cancer worldwide, is associated with a dismal prognosis that has minimally improved during the last few decades. Future advances in the treatment and prognosis of this fatal disease largely rely upo
Publikováno v:
British Journal of Cancer
Cyclopentenone 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) exerts antineoplastic effects on various types of human cancer. We recently showed that treatment with 15d-PGJ(2) induces apoptosis accompanied by downregulation of the oncogenic si
Publikováno v:
Cancer Letters. 211:97-103
Antineoplastic properties of cyclopentenone 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) involve peroxisome proliferator-activated receptor gamma (PPARgamma) dependent and independent mechanisms. We recently reported that 15d-PGJ2 inhibits cell gr
Autor:
John J. Sauk, Helen Rivera, John C. Papadimitriou, Sleygh Castillo Castillo, Hessam Siavash, Nikolaos G. Nikitakis
Publikováno v:
Journal of Oral Pathology & Medicine. 32:431-437
Background: The diffuse infiltrative lymphocytosis syndrome (DILS) in HIV patients is characterized by the persistence of CD8-circulating lymphocytes and lymphocytic infiltration, predominantly in salivary glands. Methods: We examined seven HIV-posit
Autor:
Márcio Ajudarte Lopes, Robert A. Ord, Nikolaos G. Nikitakis, Helen Rivera, Mark A. Reynolds, John J. Sauk, Hessam Siavash
Publikováno v:
American Journal of Clinical Pathology. 119:574-586
The aim of this study was to evaluate the histopathologic features and the expression of angiogenesis-related markers in primary tumors and metastatic lymph nodes of oral squamous cell carcinomas (SCCs) with multiple lymph node involvement in compari
Autor:
Anne W. Hamburger, Nikolaos G. Nikitakis, Carla Hebert, Hessam Siavash, Mark A. Reynolds, John J. Sauk
Publikováno v:
British Journal of Cancer
Activation of peroxisome proliferator-activated receptor gamma (PPARγ) has been linked to induction of differentiation, cell growth inhibition and apoptosis in several types of human cancer. However, the possible effects of PPARγ agonists on human
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 10
Hsp47 was originally discovered as a cell surface collagen binding protein, colligin, and was later shown to be an endoplasmic reticulum (ER) resident protein with collagen binding properties in chick fibroblasts. Hsp47 has been termed J6, gp46, CB48
Publikováno v:
International journal of cancer. 114(2)
Low pO2 values are a common finding among oral squamous cell carcinomas (SCC). Our objective was to determine the role that oxygen tension plays on the direct tumor effect of endostatin (ES). Squamous carcinoma cell lines were grown under normoxic or
Signal transducers and activators of transcription: insights into the molecular basis of oral cancer
Publikováno v:
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 15(5)
Recent efforts on developing more direct and effective targets for cancer therapy have revolved around a family of transcription factors known as STATs (signal transducers and activators of transcription). STAT proteins are latent cytoplasmic transcr
Autor:
Kathleen Norris, Carla Hebert, J. Stewart, Hessam Siavash, Nikolaos G. Nikitakis, John J. Sauk
Publikováno v:
Oral oncology. 39(8)
The present study sought to determine the potential role of stress activated MAPK and phosphatidylinositol 3-kinase (PI3K) signaling pathways in mediating phenotypic switching between angiogenic and angiostatic elements among squamous cell carcinoma