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Akademický článek

Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment

Autor: Wiechert Lars, Németh Julia, Pusterla Tobias, Bauer Christine, De Ponti Aurora, Manthey Sandra, Marhenke Silke, Vogel Arndt, Klingmüller Ursula, Hess Jochen, Angel Peter

Publikováno v: Cell Communication and Signaling, Vol 10, Iss 1, p 40 (2012)

Abstract Background Calprotectin consists of the Ca2+-binding proteins S100a8 and S100a9 that are induced in epithelial cells in response to tissue damage and infection. Both proteins are also secreted by activated innate immune cells and numerous st

Externí odkaz: https://doaj.org/article/819f0e6997d44ef9913eca63f6f973b3

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Akademický článek

Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells

Autor: Acuña Sanhueza Gustavo A, Faller Leonie, George Babitha, Koffler Jennifer, Misetic Vinko, Flechtenmacher Christa, Dyckhoff Gerhard, Plinkert Peter P, Angel Peter, Simon Christian, Hess Jochen

Publikováno v: BMC Cancer, Vol 12, Iss 1, p 72 (2012)

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent and lethal cancers worldwide and mortality mostly results from loco-regional recurrence and metastasis. Despite its significance, our knowledge on molecula

Externí odkaz: https://doaj.org/article/df524d7aa32a4254ba96a73d94808f28

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Akademický článek

Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation

Autor: Gebhardt Christoffer, Németh Julia, Mark Regina, Busch Hauke, Brors Benedikt, Bauer Tobias, Riehl Astrid, Bierhaus Angelika, Nawroth Peter, Eils Roland, König Rainer, Angel Peter, Hess Jochen

Publikováno v: BMC Genomics, Vol 11, Iss 1, p 537 (2010)

Abstract Background In the past, molecular mechanisms that drive the initiation of an inflammatory response have been studied intensively. However, corresponding mechanisms that sustain the expression of inflammatory response genes and hence contribu

Externí odkaz: https://doaj.org/article/eb45e21835784dc08aecece949309174

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Akademický článek

The receptor RAGE: Bridging inflammation and cancer

Autor: Hess Jochen, Angel Peter, Németh Julia, Riehl Astrid

Publikováno v: Cell Communication and Signaling, Vol 7, Iss 1, p 12 (2009)

Abstract The receptor for advanced glycation end products (RAGE) is a single transmembrane receptor of the immunoglobulin superfamily that is mainly expressed on immune cells, neurons, activated endothelial and vascular smooth muscle cells, bone form

Externí odkaz: https://doaj.org/article/24445313850e4d449792e269669fb2e6

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