Zobrazeno 1 - 10
of 951
pro vyhledávání: '"Heskamp A"'
Autor:
Daan F. Boreel, Anne P.M. Beerkens, Sandra Heskamp, Milou Boswinkel, Johannes P.W. Peters, Gosse J. Adema, Paul N. Span, Johan Bussink
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 49, Iss , Pp 100875- (2024)
Introduction: Tumor hypoxia is a feature of many solid malignancies and is known to cause radio resistance. In recent years it has become clear that hypoxic tumor regions also foster an immunosuppressive phenotype and are involved in immunotherapy re
Externí odkaz:
https://doaj.org/article/cae6230e8058466b98f4a09faac3e1ce
Autor:
Anne P. M. Beerkens, Daan F. Boreel, James A. Nathan, Jiri Neuzil, Gang Cheng, Balaraman Kalyanaraman, Micael Hardy, Gosse J. Adema, Sandra Heskamp, Paul N. Span, Johan Bussink
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background Hypoxia is a common feature of many solid tumors and causes radiotherapy and immunotherapy resistance. Pharmacological inhibition of oxidative phosphorylation (OXPHOS) has emerged as a therapeutic strategy to reduce hypoxia. Howev
Externí odkaz:
https://doaj.org/article/6158a99077a34dd2a03b9ab6923fa43f
Autor:
Wenker, S.T.M., van Lith, S.A.M., Tamborino, G., Konijnenberg, M.W., Bussink, J., Heskamp, S.
Publikováno v:
In Nuclear Medicine and Biology January-February 2025 140-141
Autor:
Boreel, Daan F., Beerkens, Anne P.M., Heskamp, Sandra, Boswinkel, Milou, Peters, Johannes P.W., Adema, Gosse J., Span, Paul N., Bussink, Johan
Publikováno v:
In Clinical and Translational Radiation Oncology November 2024 49
Autor:
Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy Lloyd, Vitalijs Ovcinnikovs, Gijs G. Zom, Renoud J. Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin G. W. Sandker, Sandra Heskamp, Sjoerd H. van der Burg, Tsolere Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CD3 bispecific antibody (CD3 bsAb) therapy is clinically approved for refractory hematological malignancies, but responses in solid tumors have been limited so far. One of the main hurdles in solid tumors is the lack of sufficient T-cell inf
Externí odkaz:
https://doaj.org/article/36795cab2cda485e96053669065dc63a
Autor:
Heskamp, Linda, Birkbeck, Matthew G., Hall, Julie, Schofield, Ian.S., Bashford, James, Williams, Timothy L., De Oliveira, Hugo M., Whittaker, Roger G., Blamire, Andrew M.
Publikováno v:
In Clinical Neurophysiology May 2024 161:246-255
Autor:
Sanne C.C. Vincenten, Karlien Mul, Daniël vanAs, Julia J. Jansen, Linda Heskamp, Arend Heerschap, Baziel G.M. vanEngelen, Nicol C. Voermans
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1695-1706 (2023)
Abstract Background It is unclear how changes in quantitative muscle magnetic resonance imaging (MRI) relate to changes in clinical outcome in facioscapulohumeral muscular dystrophy (FSHD), although this information is crucial for optimal use of MRI
Externí odkaz:
https://doaj.org/article/9f75fa9bef2e4cbab604efb78a1219d3
Autor:
Oprea-Lager, Daniela-Elena, MacLennan, Steven, Bjartell, Anders, Briganti, Alberto, Burger, Irene A., de Jong, Igle, De Santis, Maria, Eberlein, Uta, Emmett, Louise, Fizazi, Karim, Gillessen, Silke, Herrmann, Ken, Heskamp, Sandra, Iagaru, Andrei, Jereczek-Fossa, Barbara Alicja, Kunikowska, Jolanta, Lam, Marnix, Nanni, Cristina, O'Sullivan, Joe M., Panebianco, Valeria, Sala, Evis, Sathekge, Mike, Sosnowski, Roman, Tilki, Derya, Tombal, Bertrand, Treglia, Giorgio, Tunariu, Nina, Walz, Jochen, Yakar, Derya, Dierckx, Rudi, Sartor, Oliver, Fanti, Stefano
Publikováno v:
In European Urology January 2024 85(1):49-60
Autor:
Milou Boswinkel, René Raavé, Andor Veltien, Tom WJ Scheenen, Nina Fransén Petterson, René in ‘t Zandt, Lars E. Olsson, Karin von Wachenfeldt, Sandra Heskamp, Irma Mahmutovic Persson
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2023)
ObjectiveAccurate imaging biomarkers that indicate disease progression at an early stage are highly important to enable timely mitigation of symptoms in progressive lung disease. In this context, reproducible experimental models and readouts are key.
Externí odkaz:
https://doaj.org/article/a405629d6a6940eca5062731026e2424
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-12 (2022)
Heskamp et al. perform quantitative MRI analysis of end-to-end muscle fat fractions in a series of patients with facioscapulohumeral dystrophy. The authors report that disease initiation commonly occurs at the distal end of affected muscles, with wav
Externí odkaz:
https://doaj.org/article/331a61bf3cdf4e8abb2d159e0ddf1d4a