Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Hesham, Saeed"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9086 (2024)
Cancer cells can escape death and surveillance by the host immune system in various ways. Programmed cell death ligand 1 (PD-L1) is a transmembrane protein that is expressed by most cell types, including cancer cells, and can provide an inhibitory si
Externí odkaz:
https://doaj.org/article/8ef7d2cd241b45db9bb71ba5abb59579
Autor:
Mohammed Moustapha Anwar, Manal Aly Shalaby, Hesham Saeed, Haitham Mohammed Mostafa, Dalia Galal Hamouda, Howaida Nounou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Nile Tilapia fish scale collagen has high biodegradability, excellent biocompatibility, and low antigenicity. We assessed both the encapsulation efficiency of theophylline into Nile Tilapia fish scale-based collagen nanoparticles and their s
Externí odkaz:
https://doaj.org/article/df5d5c895ec2423eadd6b30aef5bacdf
Autor:
Manal Shalaby, Dalia Hamouda, Shaimaa M Khedr, Haitham M Mostafa, Hesham Saeed, Ahmed Z Ghareeb
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0282557 (2023)
The creation of innovative wound-healing nanomaterials based on natural compounds emerges as a top research goal. This research aimed to create a gel containing collagen nanoparticles and evaluate its therapeutic potential for skin lesions. Collagen
Externí odkaz:
https://doaj.org/article/4b3958e6d2a7450d8cfea9763ecc4135
Autor:
Diana K. Ghobrial, Nefertiti El-Nikhely, Eman Sheta, Hanan M. Ragab, Sherif A. F. Rostom, Hesham Saeed, Ahmed Wahid
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 637 (2023)
Liver Fibrosis can be life-threatening if left untreated as it may lead to serious, incurable complications. The common therapeutic approach is to reverse the fibrosis while the intervention is still applicable. Celecoxib was shown to exhibit some an
Externí odkaz:
https://doaj.org/article/2599163c563449319823adfd395d4604
Autor:
Nehad Noby, Husam Sabah Auhim, Samuel Winter, Harley L. Worthy, Amira M. Embaby, Hesham Saeed, Ahmed Hussein, Christopher R. Pudney, Pierre J. Rizkallah, Stephen A. Wells, D. Dafydd Jones
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Here we determined the structure of a cold active family IV esterase (EstN7) cloned from Bacillus cohnii strain N1. EstN7 is a dimer with a classical α/β hydrolase fold. It has an acidic surface that is thought to play a role in cold-adaption by re
Externí odkaz:
https://doaj.org/article/742a9bfe43b248879d57a96a80adc331
Autor:
Nehad Noby, Rachel L. Johnson, Jonathan D. Tyzack, Amira M. Embaby, Hesham Saeed, Ahmed Hussein, Sherine N. Khattab, Pierre J. Rizkallah, D. Dafydd Jones
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4703 (2022)
Cold active esterases have gained great interest in several industries. The recently determined structure of a family IV cold active esterase (EstN7) from Bacillus cohnii strain N1 was used to expand its substrate range and to probe its commercially
Externí odkaz:
https://doaj.org/article/c84c2e55ae7a489fbd5916ac8cbcd1fe
Autor:
Manal Abdel-Fattah, Hesham Saeed, Lamiaa El-Shennawy, Manal Shalaby, Amira Embaby, Farid Ataya, Hoda Mahmoud, Ahmed Hussein
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0213880 (2019)
The current study highlights, for the first time, cloning, overexpression and purification of the novel interferon epsilon (IFNƐ), from the Arabian camel Camelus dromedaries. The study then assesses the cytotoxicity of IFNε against two human breast
Externí odkaz:
https://doaj.org/article/b7ef1278b7a7441e9eeb55341b93817f
Publikováno v:
Polymers and Polymer Composites. 29:1515-1527
The public concern for industrial pollution is urging for an economical solution to remove industrial effluent that increases the risk of human cancers. Currently, there are a few successful techniques implemented for dye removal; however, little has
Publikováno v:
Journal of Polymer Research. 29
Nanoparticles are the gateway to the new era in drug delivery of biocompatible agents. Several products have emerged from nanomaterials in quest of developing practical wound healing dressings that are nonantigenic, antishear stress, and gas-exchange
Autor:
Hesham Saeed, Amira M. Embaby, Ahmed Hussein, Manal Shalaby, Mohammed Moustapha Anwar, Mona M. Agwa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Prodigiosin, a secondary metabolite red pigment produced by Serratia marcescens, has an interesting apoptotic efficacy against cancer cell lines with low or no toxicity on normal cells. HSP90α is known as a crucial and multimodal target in the treat