Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Hesam Dashti"'
Autor:
Danielle Rasooly, Gina M. Peloso, Alexandre C. Pereira, Hesam Dashti, Claudia Giambartolomei, Eleanor Wheeler, Nay Aung, Brian R. Ferolito, Maik Pietzner, Eric H. Farber-Eger, Quinn Stanton Wells, Nicole M. Kosik, Liam Gaziano, Daniel C. Posner, A. Patrícia Bento, Qin Hui, Chang Liu, Krishna Aragam, Zeyuan Wang, Brian Charest, Jennifer E. Huffman, Peter W. F. Wilson, Lawrence S. Phillips, John Whittaker, Patricia B. Munroe, Steffen E. Petersen, Kelly Cho, Andrew R. Leach, María Paula Magariños, John Michael Gaziano, VA Million Veteran Program, Claudia Langenberg, Yan V. Sun, Jacob Joseph, Juan P. Casas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract We conduct a large-scale meta-analysis of heart failure genome-wide association studies (GWAS) consisting of over 90,000 heart failure cases and more than 1 million control individuals of European ancestry to uncover novel genetic determinan
Externí odkaz:
https://doaj.org/article/121bbc31eec24459b300c8546850ced3
Autor:
Saaket Agrawal, Minxian Wang, Marcus D. R. Klarqvist, Kirk Smith, Joseph Shin, Hesam Dashti, Nathaniel Diamant, Seung Hoan Choi, Sean J. Jurgens, Patrick T. Ellinor, Anthony Philippakis, Melina Claussnitzer, Kenney Ng, Miriam S. Udler, Puneet Batra, Amit V. Khera
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The inherited basis of body fat distribution is not fully understood. Here, the authors use genetic data and MRI-derived measures of local adiposity to highlight fat depot-specific genetic architecture with implications for cardiometabolic health.
Externí odkaz:
https://doaj.org/article/708f44bb6b094581a53300838b54ced3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Although models have been developed for predicting severity of COVID-19 from the medical history of patients, simplified models with good accuracy could be more practical. In this study, we examined utility of simpler models for estimating r
Externí odkaz:
https://doaj.org/article/6bbff66c1d6448228591636cfd44411a
Autor:
Olga V. Demler, Yanyan Liu, Heike Luttmann-Gibson, Jeramie D. Watrous, Kim A. Lagerborg, Hesam Dashti, Franco Giulianini, Mallory Heath, Carlos A. Camargo, William S. Harris, Jay G. Wohlgemuth, Allen M. Andres, Saumya Tivari, Tao Long, Mahan Najhawan, Khoi Dao, James G. Prentice, Julia A. Larsen, Olivia I. Okereke, Karen H. Costenbader, Julie E. Buring, JoAnn E. Manson, Susan Cheng, Mohit Jain, Samia Mora
Publikováno v:
Metabolites, Vol 10, Iss 11, p 431 (2020)
Omega-3 (n-3) treatment may lower cardiovascular risk, yet its effects on the circulating lipidome and relation to cardiovascular risk biomarkers are unclear. We hypothesized that n-3 treatment is associated with favorable changes in downstream fatty
Externí odkaz:
https://doaj.org/article/83c39b76471a4147acd90b85adca4e35
Autor:
Aniket N Zinzuwadia, Chunying Li, Hesam Dashti, Lin Chen, Brian Cade, Elizabeth Karlson, Nina Paynter, Samia Mora, Olga Demler
Publikováno v:
Circulation. 145
Introduction: The Pooled Cohort Equations (PCE) are the clinical standard for risk estimation of 10-year ASCVD risk, but they have not been extensively validated in minority populations or compared with newer risk estimation calculators such as the M
Publikováno v:
Nature Machine Intelligence
Nat Mach Intell
Nat Mach Intell
Recent technological advances may lead to the development of small-scale quantum computers that are capable of solving problems that cannot be tackled with classical computers. A limited number of algorithms have been proposed and their relevance to
Autor:
Angelica Di Vincenzo, Molly L. Veregge, Samuel J. Lin, Christopher G. Boyd, Adam Essene, Elizabeth McGonagle, Zachary Kramer, Melina Claussnitzer, Anja Jørgensen, Samantha Laber, Tune H. Pers, Margo P. Emont, Antonio Giordano, Eleanna De Filippis, Christopher Jacobs, Aviv Regev, Georgia Colleluori, Deepti Pant, William Gourash, Anton Gulko, Saaket Agrawal, Gregory P. Westcott, Danielle Tenen, Erin Merkel, Anita P. Courcoulas, Linus Tsai, Sophie Strobel, Adam Stefek, Evan D. Rosen, Orr Ashenberg, Hesam Dashti, Harini Srinivasan, Jennifer Ducie, Donald Morris, Bernard T. Lee, Amrita Kar, Amit Khera, Adam M. Tobias
White adipose tissue (WAT), once regarded as morphologically and functionally bland, is now recognized to be dynamic, plastic, heterogenous, and involved in a wide array of biological processes including energy homeostasis, glucose and lipid handling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b64205c47b354a8b6533c3b86b88af0
https://doi.org/10.1101/2021.11.09.466968
https://doi.org/10.1101/2021.11.09.466968
Publikováno v:
Advances in experimental medicine and biology. 1325
Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for approximately 18 million deaths in 2017. Coronary artery disease is the predominant cause of death from CVD, followed by stroke. Owing to recent technological advanc
Autor:
Anthony A. Philippakis, Marcus D. R. Klarqvist, Joseph Shin, Seung Hoan Choi, Melina Claussnitzer, Amit Khera, Sean J. Jurgens, Kenney Ng, Puneet Batra, Patrick T. Ellinor, Hesam Dashti, Nathaniel Diamant, Minxian Wang, Saaket Agrawal
For any given level of overall adiposity – as commonly quantified by body mass index (BMI) within clinical practice – individuals vary considerably in fat distribution. We and others have noted that increased visceral fat (VAT) is associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8042962061c7348545901546161cf4eb
https://doi.org/10.1101/2021.08.24.21262564
https://doi.org/10.1101/2021.08.24.21262564
Autor:
Yulia Pustovalova, Frank Delaglio, D. Levi Craft, Haribabu Arthanari, Ad Bax, Martin Billeter, Mark J. Bostock, Hesam Dashti, D. Flemming Hansen, Sven G. Hyberts, Bruce A. Johnson, Krzysztof Kazimierczuk, Hengfa Lu, Mark Maciejewski, Tomas M. Miljenovic, Mehdi Mobli, Daniel Nietlispach, Vladislav Orekhov, Robert Powers, Xiaobo Qu, Scott Anthony Robson, David Rovnyak, Gerhard Wagner, Jinfa Ying, Matthew Zambrello, Jeffrey C. Hoch, David L. Donoho, Adam D. Schuyler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3cc65231b8817a82cba9899a68afcd6
https://doi.org/10.5194/mr-2021-59-supplement
https://doi.org/10.5194/mr-2021-59-supplement