Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Herwart F, Otto"'
Publikováno v:
Journal of Cellular and Molecular Medicine
The longest open reading frame of PKHD1 (polycystic kidney and hepatic disease 1), the autosomal recessive polycystic kidney disease (ARPKD) gene, encodes a single-pass, integral membrane protein named polyductin or fibrocystin. A fusion protein comp
Autor:
Herwart F. Otto, Consolato Sergi, Walter J. Hofmann, Dietrich Feist, Julia Benstz, Walter Nützenadel
Publikováno v:
Pathology. 40:260-267
To validate the bile duct to portal space ratio as an independent factor useful for the prognosis of neonatal liver disease.We assessed the maturation of the intrahepatic bile duct system (IBDS) in 87 consecutive infants aged less than 1 year undergo
Autor:
Sebastian Aulmann, Falk-Udo Sack, Peter Schirmacher, Philipp A. Schnabel, Ralf J. Rieker, Hendrik Bläker, Gunhild Mechtersheimer, Herwart F. Otto
Publikováno v:
Pathology & Oncology Research. 11:57-60
Thymic cysts are rare lesions located along the anatomical course of the third pharyngeal pouch. While most of the cases represent congenital cysts, they may also be related to neoplasms. We report a case of a micronodular thymoma with lymphoid strom
Autor:
Philipp A. Schnabel, Herwart F. Otto, Hans-Peter Sinn, Sebastian Aulmann, Hendrik Dienemann, Peter Drings, Birgit Helmchen
Publikováno v:
Virchows Archiv. 446:305-309
Primary acantholytic squamous cell carcinoma (ASCC) of the breast is a rare and aggressive variant of invasive breast cancer. Here we report two new cases of ASCC and their immunohistochemical and cytogenetic characterization. One case was associated
Autor:
Nikolaus Gassler, Herwart F. Otto, Marianne Thome, Burkhard Helmke, Wolfgang Wahl, Annemarie Poustka, Stefan Lyer, Jan Mollenhauer, Martin Deichmann, Axel Benner, Christel Herold-Mende
Publikováno v:
Helmke, B M, Mollenhauer, J, Herold-Mende, C, Benner, A, Thome, M, Gassler, N, Wahl, W, Lyer, S, Poustka, A, Otto, H F & Deichmann, M 2004, ' BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level. ', Gastroenterology, vol. 127, no. 6, pp. 1815-20 .
Udgivelsesdato: 2004-Dec BACKGROUND & AIMS: Anorectal melanoma (AM) is a rare but highly malignant tumor, displaying histologic and immunohistochemical features very similar to cutaneous melanoma (CM). Because BRAF mutations were recently identified
Autor:
Hendrik Bläker, Herwart F. Otto, Magnus von Knebel-Doeberitz, Burkhard Helmke, Christian Sutter, Martina Kadmon, Johannes Gebert
Publikováno v:
Genes, Chromosomes and Cancer. 41:93-98
Patients with familial adenomatous polyposis coli (FAP) carry heterozygous mutations of the APC gene. At a young age, these patients develop multiple colorectal adenomas that consistently display a second somatic mutation in the remaining APC wild-ty
Autor:
Roland Penzel, Birgit Helmchen, Sebastian Aulmann, Ralf J. Rieker, Hendrik Bläker, Herwart F. Otto
Publikováno v:
Pathology - Research and Practice. 200:1-7
Despite morphological similarities between adenocarcinomas of the small and the large intestine, recent evidence suggests that both tumor types follow different genetic pathways. In particular, inactivation of the APC tumor suppressor gene, a charact
Publikováno v:
Der Pathologe. 25:155-159
Die Krankengeschichte einer 65 Jahre alten Frau mit in die Gallenblase metastasiertem malignem Melanom wird geschildert. Die wegen einer Cholezystitis resezierte Gallenblase zeigte einen knotigen, dunkel pigmentierten Tumor auf den Schnittflachen. Du
Autor:
Birgit Ottenwälder, Nikolaus Gassler, Herwart F. Otto, Jürgen Kopitz, Annemarie Poustka, Frank Autschbach, Arman Tehrani, Jan Mollenhauer, Stefan Lyer, Martina Schnölzer, Jürgen Kartenbeck
Publikováno v:
The Journal of Pathology. 202:188-196
Several disorders of the small intestine are associated with disturbances in villus architecture. Thus, an understanding of the molecular mechanisms associated with the differentiation of villi represents an important step in the improvement of the u
Autor:
Falk-Udo Sack, Herwart F. Otto, Siegfried Hagl, Sarah Taylor, Thomas J. Vielfort, Philipp A. Schnabel, Markus Haass, Achim Koch
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 25:91-97
Objective: Platelet-derived growth factor (PDGF) plays an important role in structural alterations of blood vessels after heart transplantation (HTx). The aim of this study was to clarify the effect of peritransplant injury and postoperative complica