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pro vyhledávání: '"Herve Duclohier"'
Publikováno v:
Journal of Peptide Science. 9:776-783
The multiple conductance levels displayed by the antibiotic alamethicin in planar lipid bilayers is explained by a dynamic ‘barrel-stave’ model, the conducting pore resulting from the aggregation of up to ten helical amphipathic helical monomers.
Autor:
Herve Duclohier
Publikováno v:
European biophysics journal : EBJ. 33(3)
Kinks or bends introduced in peptides and proteins by “helical distorter” residues such as proline, other imino acids and glycine, especially when these are in close proximity in the sequence, are increasingly recognized as playing an essential r
Autor:
Herve Duclohier
Publikováno v:
Mini reviews in medicinal chemistry. 2(4)
Animals and plants defend themselves against pathogenic micro-organisms by the rapid mobilization of polycationic helical amphipathic peptides. Interactions with membranes induce optimal orientation and mutual structural changes, allowing for example