Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hervé Toutain"'
Autor:
Wim J.A. Meuling, Hervé Toutain, Rolf Fautz, Wouter H.J. Vaes, Julie A. Skare, W. Steiling, Kenneth R. Wehmeyer, Gerhard J. Nohynek, Eric K. Dufour, Mario Bramante, Albertus Th H.J. de Bie
Publikováno v:
Food and Chemical Toxicology. 81:71-80
Systemic exposure was measured in humans after hair dyeing with oxidative hair dyes containing 2.0% (A) or 1.0% (B) [14C]-p-phenylenediamine (PPD). Hair was dyed, rinsed, dried, clipped and shaved; blood and urine samples were collected for 48 hours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a9f63c805e379ae129f525670a92584
https://doi.org/10.1016/j.fct.2015.04.003
https://doi.org/10.1016/j.fct.2015.04.003
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 672:21-26
Retinyl palmitate (RP), an ingredient of cosmetic and medical skin-care preparations, has been reported to be photo-genotoxic/photo-clastogenic in mouse lymphoma cells (Tk locus) as well as in human Jurkat T-cells, as measured by use of the comet ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6db7511d89bc1e5a7b94f66126f5da
https://doi.org/10.1016/j.mrgentox.2008.09.019
https://doi.org/10.1016/j.mrgentox.2008.09.019
Autor:
Alexa Patzelt, Christèle Ribaud, Hans Schaefer, Jacques Leclaire, Heike Richter, F. Benech-Kieffer, Gerhard J. Nohynek, Hervé Toutain, Frédérique Hueber-Becker, Wolfram Sterry, Ute Jacobi, Eric K. Dufour, Juergen Lademann
Publikováno v:
Food and Chemical Toxicology. 46:2214-2223
Although in vitro skin absorption studies often detect small residues of applied test material in the epidermis/dermis, it is uncertain whether the residue is within the living skin. We studied the dermal absorption of a hair dye hydroxyanthraquinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6891ab1e43ffdc27c7e09646a19f5379
https://doi.org/10.1016/j.fct.2008.02.018
https://doi.org/10.1016/j.fct.2008.02.018
Autor:
Albertus Th H.J. de Bie, Eric K. Dufour, Frédérique Hueber-Becker, Gerhard J. Nohynek, Hervé Toutain, Hermann M. Bolt, W.J.A. Meuling
Publikováno v:
Food and Chemical Toxicology. 45:160-169
We monitored the exposure of hairdressers to oxidative hair dyes for 6 working days under controlled conditions. Eighteen professional hairdressers (3/day) coloured hairdresser's training heads bearing natural human hair (hair length: approximately 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aecd000ae8b029e5684e700af62ec5
https://doi.org/10.1016/j.fct.2006.08.002
https://doi.org/10.1016/j.fct.2006.08.002
Autor:
Gerhard J. Nohynek, Alexia Garrigues, Jacques Leclaire, Hervé Toutain, Pierre-Alain Meunier, Daniel Duche
Publikováno v:
Toxicology Letters. 158:196-212
We investigated the biotransformation of the oxidative arylamine (AA) hair dye ingredients [14C]-para-aminophenol (PAP) and [14C]-para-phenylenediamine (PPD) in reconstructed human epidermis and human hepatocytes. Human epidermis quantitatively trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b19d4eb0173b280a7902743189f706
https://doi.org/10.1016/j.toxlet.2005.03.014
https://doi.org/10.1016/j.toxlet.2005.03.014
Publikováno v:
Food and Chemical Toxicology. 42:517-543
Hair dyes and their ingredients have moderate to low acute toxicity. Human poisoning accidents are rare and have only been reported following oral ingestion. Contact sensitisation to hair dyes has been a safety issue, mainly as a consequence of unpro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529a9064dbff1a0bc4f18f88a7387817
https://doi.org/10.1016/j.fct.2003.11.003
https://doi.org/10.1016/j.fct.2003.11.003
Autor:
Hiroyuki Jinnai, Daniel Marzin, Christele Leclerc-Ribaud, Hervé Toutain, David Kirkland, Gerhard J. Nohynek
Publikováno v:
Food and Chemical Toxicology. 42:93-105
Kojic acid (KA), a natural substance produced by fungi or bacteria, such as Aspergillus, Penicillium or Acetobacter spp, is contained in traditional Japanese fermented foods and is used as a dermatological skin-lightening agent. High concentrations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd82bfb9653aa0806131a5638f5ee1c
https://doi.org/10.1016/j.fct.2003.08.008
https://doi.org/10.1016/j.fct.2003.08.008
Autor:
Andrea Trevisan, Gabrielle M. Hawksworth, Fons A.J.J.L. Rutten, Jacques E. Diezi, Walter Pfaller, Peter H. Bach, Hervé Toutain, Ernest Harpur, Edward A. Lock, Jean-Paul Morin, Michael P. Ryan, Caroline MacDonald, J. Fred Nagelkerke, Wolfgang Dekant
Publikováno v:
Alternatives to Laboratory Animals. 23:713-727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9c2c19014c94104a2ada35f4e5cbea
https://doi.org/10.1177/026119299502300525
https://doi.org/10.1177/026119299502300525
Autor:
Hervé Toutain, Françoise Courjault
Publikováno v:
Alternatives to Laboratory Animals. 21:30-37
Nephrotoxicity is one of the most important dose-limiting side-effects of cis-diaminedichloroplatinum (II) (cDDP) in humans. Quiescent OK cells grown in hormonally-defined, serum-free medium in the total absence of antibiotics were used to study the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72da54ff240383290b94d94928fd4cd8
https://doi.org/10.1177/026119299302100106
https://doi.org/10.1177/026119299302100106
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 49(2)
The key issue of the safety assessment of botanical ingredients in personal care products (PCP) is the phytochemical characterisation of the plant source, data on contamination, adulteration and hazardous residues. The comparative approach used in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dda2f519a60dfc63bc8f2f7fdda15c9
https://pubmed.ncbi.nlm.nih.gov/21111022
https://pubmed.ncbi.nlm.nih.gov/21111022