Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hervé Pagès"'
Autor:
Lihua Julie Zhu, Michael Lawrence, Ankit Gupta, Hervé Pagès, Alper Kucukural, Manuel Garber, Scot A. Wolfe
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Genome editing technologies developed around the CRISPR-Cas9 nuclease system have facilitated the investigation of a broad range of biological questions. These nucleases also hold tremendous promise for treating a variety of genet
Externí odkaz:
https://doaj.org/article/4193e04907d7485d9ad9fe1f6d11f939
Autor:
Shweta Gopaulakrishnan, Samuela Pollack, BJ Stubbs, Hervé Pagès, John Readey, Sean Davis, Levi Waldron, Martin Morgan, Vincent Carey
Publikováno v:
F1000Research, Vol 8 (2019)
Bioconductor's SummarizedExperiment class unites numerical assay quantifications with sample- and experiment-level metadata. SummarizedExperiment is the standard Bioconductor class for assays that produce matrix-like data, used by over 200 packages.
Externí odkaz:
https://doaj.org/article/abbb06e3ae4144998b3fa3a2a79af8f5
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 5, p e1006135 (2018)
Biological experiments involving genomics or other high-throughput assays typically yield a data matrix that can be explored and analyzed using the R programming language with packages from the Bioconductor project. Improvements in the throughput of
Externí odkaz:
https://doaj.org/article/23478ab922484ce691f778aeb3f1810a
Autor:
Michael Lawrence, Wolfgang Huber, Hervé Pagès, Patrick Aboyoun, Marc Carlson, Robert Gentleman, Martin T Morgan, Vincent J Carey
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 8, p e1003118 (2013)
We describe Bioconductor infrastructure for representing and computing on annotated genomic ranges and integrating genomic data with the statistical computing features of R and its extensions. At the core of the infrastructure are three packages: IRa
Externí odkaz:
https://doaj.org/article/1bbc275c431c49e095926a193427e71b
Autor:
Anastassiia Vertii, Hervé Pagès, Lihua Julie Zhu, Jianhong Ou, Aimin Yan, Haibo Liu, Paul D. Kaufman, Jun Yu
In interphase eukaryotic cells, almost all heterochromatin is located adjacent to the nucleolus or to the nuclear lamina, thus defining Nucleolus-Associated Domains (NADs) and Lamina–Associated Domains (LADs), respectively. Here, we determined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a3b61fecb37e0a76ff082a3d575e90
Autor:
Hervé Pagès, Martin Morgan, Charlotte Soneson, Raphael Gottardo, Stephanie C. Hicks, Ludwig Geistlinger, Robert A. Amezquita, Vincent J. Carey, Levi Waldron, Federico Marini, Lindsay N. Carpp, Lun Atl., Etienne Becht, Wolfgang Huber, Davide Risso, Michael L. Smith, Kevin Rue-Albrecht
Publikováno v:
Nature Methods. 17:242-242
Autor:
Paul Shannon, Kasper D. Hansen, Sean Davis, Vincent J. Carey, Benilton S. Carvalho, Marc R. J. Carlson, Thomas Girke, Valerie Obenchain, Martin Morgan, Raphael Gottardo, Rafael A. Irizarry, Dan Tenenbaum, Hervé Pagès, Héctor Corrada Bravo, Alejandro Reyes, Michael I. Love, Robert Gentleman, James W. MacDonald, Simon Anders, Florian Hahne, Levi Waldron, Andrzej K. Oleś, Wolfgang Huber, Michael S. Lawrence, Gordon K. Smyth, Laurent Gatto
Publikováno v:
Nature Methods
Nature methods, Vol. 12, no.2, p. 115-21 (2015)
Nature methods, Vol. 12, no.2, p. 115-21 (2015)
Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development
Recent advances in single-cell RNA sequencing have dramatically increased the number of cells that can be profiled in a single experiment. This provides unparalleled resolution to study cellular heterogeneity within biological processes such as diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeed185a842ee2d0c1f5ce918edc4642
https://doi.org/10.1101/167445
https://doi.org/10.1101/167445
Autor:
Alper Kucukural, Lihua Julie Zhu, Michael S. Lawrence, Ankit Gupta, Scot A. Wolfe, Hervé Pagès, Manuel Garber
Publikováno v:
BMC Genomics
BMC Genomics, Vol 18, Iss 1, Pp 1-10 (2017)
BMC Genomics, Vol 18, Iss 1, Pp 1-10 (2017)
Background Genome editing technologies developed around the CRISPR-Cas9 nuclease system have facilitated the investigation of a broad range of biological questions. These nucleases also hold tremendous promise for treating a variety of genetic disord
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1418
Annotation resources make up a significant proportion of the Bioconductor project (Huber et al., Nat Methods 12:115-121, 2015). And there are also a diverse set of online resources available which are accessed using specific packages. Here we describ