Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hervé Nicoloff"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Heteroresistance is a medically relevant phenotype where small antibiotic-resistant subpopulations coexist within predominantly susceptible bacterial populations. Heteroresistance reduces treatment efficacy across diverse bacterial species a
Externí odkaz:
https://doaj.org/article/6ed77ced59eb408aacdf181b48e07220
Publikováno v:
PLoS Biology, Vol 22, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/7092c049509b472f85ec29a38dc3e005
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001808 (2022)
In a collection of Escherichia coli isolates, we discovered a new mechanism leading to frequent and high-level tigecycline resistance involving tandem gene amplifications of an efflux pump encoded by the tet(A) determinant. Some isolates, despite car
Externí odkaz:
https://doaj.org/article/1ebafde0b5ed47b1bca44c1444d0734a
Autor:
David R. Olivenza, Hervé Nicoloff, María Antonia Sánchez-Romero, Ignacio Cota, Dan I. Andersson, Josep Casadesús
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract We describe a portable epigenetic switch based on opvAB, a Salmonella enterica operon that undergoes bistable expression under DNA methylation control. A DNA fragment containing the opvAB promoter and the opvAB upstream regulatory region con
Externí odkaz:
https://doaj.org/article/b36d5c100fd74377906c0304d92d7e3f
Publikováno v:
Nature Reviews Microbiology. 17:479-496
Antibiotic heteroresistance is a phenotype in which a bacterial isolate contains subpopulations of cells that show a substantial reduction in antibiotic susceptibility compared with the main population. Recent work indicates that heteroresistance is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459bfd982977d22e2502f5034adc9103
https://doi.org/10.1038/s41579-019-0218-1
https://doi.org/10.1038/s41579-019-0218-1
Publikováno v:
Nature Microbiology. 4:504-514
When choosing antibiotics to treat bacterial infections, it is assumed that the susceptibility of the target bacteria to an antibiotic is reflected by laboratory estimates of the minimum inhibitory concentration (MIC) needed to prevent bacterial grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80375ebcbcff8b4acd6d53e9dd1bbcca
https://doi.org/10.1038/s41564-018-0342-0
https://doi.org/10.1038/s41564-018-0342-0
Autor:
Hervé Nicoloff, María Antonia Sánchez-Romero, Dan I. Andersson, Ignacio Cota, David R. Olivenza, Josep Casadesús
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports
Scientific Reports
We describe a portable epigenetic switch based on opvAB, a Salmonella enterica operon that undergoes bistable expression under DNA methylation control. A DNA fragment containing the opvAB promoter and the opvAB upstream regulatory region confers bist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49529ac8f1fe6e440fbb08674f582eae
https://doi.org/10.1038/s41598-019-54657-2
https://doi.org/10.1038/s41598-019-54657-2
Autor:
Hervé Nicoloff, Dan I. Andersson
Publikováno v:
Molecular Microbiology. 90:1233-1248
Previous work demonstrated that selection for Escherichia coli mutants with low antibiotic resistance frequently resulted in co-selection of lon mutations and that lon(-) mutants evolved higher-level resistance faster than a lon(+) strain. Here we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::902b04788f91ebbf0749ae52eaef8aa5
https://doi.org/10.1111/mmi.12429
https://doi.org/10.1111/mmi.12429
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:4944-4948
Transposon inactivation of ycgE , a gene encoding a putative transcriptional regulator, led to decreased multidrug susceptibility in an Escherichia coli lon mutant. The multidrug susceptibility phenotype (e.g., to tetracycline and β-lactam antibioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1630d46c8390ce7214bd39515e7f004
https://doi.org/10.1128/aac.00787-09
https://doi.org/10.1128/aac.00787-09
Autor:
Dan I. Andersson, Hervé Nicoloff
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(1)
Objectives: The detection of indirect resistance in vitro suggests that coinfecting bacteria from the normal microbial flora may have a more important negative impact during antimicrobial therapy than is generally appreciated.Indirect resistance (IR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ab593725c9a6f3e320de86db68fc1c
https://pubmed.ncbi.nlm.nih.gov/26467993
https://pubmed.ncbi.nlm.nih.gov/26467993