Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Hervé Leh"'
Autor:
Hoda Jaffal, Mounia Kortebi, Pauline Misson, Paulo Tavares, Malika Ouldali, Hervé Leh, Sylvie Lautru, Virginia S Lioy, François Lecointe, Stéphanie G Bury-Moné
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002725 (2024)
Streptomyces are renowned for their prolific production of specialized metabolites with applications in medicine and agriculture. These multicellular bacteria present a sophisticated developmental cycle and play a key role in soil ecology. Little is
Externí odkaz:
https://doaj.org/article/827aab83e6284f32b0edabf581bc6442
Autor:
Virginia S. Lioy, Jean-Noël Lorenzi, Soumaya Najah, Thibault Poinsignon, Hervé Leh, Corinne Saulnier, Bertrand Aigle, Sylvie Lautru, Annabelle Thibessard, Olivier Lespinet, Pierre Leblond, Yan Jaszczyszyn, Kevin Gorrichon, Nelle Varoquaux, Ivan Junier, Frédéric Boccard, Jean-Luc Pernodet, Stéphanie Bury-Moné
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Streptomyces bacteria have a linear chromosome, with core genes located in the central region and gene clusters for specialized metabolite biosynthesis found in the ‘arms’. Here, Lioy et al. show that such chromosome structure correlates with gen
Externí odkaz:
https://doaj.org/article/69ebdcca68044d26ae4c0c82ce1b8f3e
Autor:
Anne-Sophie L'Honneur, Hervé Leh, Fanny Laurent-Tchenio, Uriel Hazan, Flore Rozenberg, Stéphanie Bury-Moné
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199171 (2018)
JC virus (JCV), a ubiquitous human polyomavirus, can cause fatal progressive multifocal leukoencephalopathy (PML) in immune compromised patients. The viral genome is composed of two conserved coding regions separated by a highly variable non-coding c
Externí odkaz:
https://doaj.org/article/8cec624ad6434b35a10cc9aeace03d60
Autor:
Hervé Leh, Ahmad Khodr, Marie-Christine Bouger, Bianca Sclavi, Sylvie Rimsky, Stéphanie Bury-Moné
Publikováno v:
mBio, Vol 8, Iss 4 (2017)
ABSTRACT In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis. This pathogenicity island comprises five major operons (LEE1 to LEE5), with the LEE5 o
Externí odkaz:
https://doaj.org/article/5ae46e1209944260afa503519718e732
Autor:
Paulina Prorok, Christine Saint-Pierre, Didier Gasparutto, Olga S. Fedorova, Alexander A. Ishchenko, Hervé Leh, Malcolm Buckle, Barbara Tudek, Murat Saparbaev
Publikováno v:
PLoS ONE, Vol 8, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/0b191d82fb414bb09ca78d7a3923ba59
Autor:
Elvire Beleoken, Hervé Leh, Armelle Arnoux, Béatrice Ducot, Claude Nogues, Eleonora De Martin, Catherine Johanet, Didier Samuel, Mohammad Zahid Mustafa, Jean-Charles Duclos-Vallée, Malcolm Buckle, Eric Ballot
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84600 (2013)
BACKGROUND: Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is a target for antinuclear autoantibodies in systemic Lupus erythematosus (SLE), rheumatoid arthritis (RA), and autoimmune hepatitis (AIH). AIM: To monitor molecular interactions betw
Externí odkaz:
https://doaj.org/article/e9db935d70e1416eb151e65a7899fe13
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44287 (2012)
Non-specific binding to biosensor surfaces is a major obstacle to quantitative analysis of selective retention of analytes at immobilized target molecules. Although a range of chemical antifouling monolayers has been developed to address this problem
Externí odkaz:
https://doaj.org/article/b72d5d13c22c435aae6484bc149c8035
Autor:
Paulina Prorok, Christine Saint-Pierre, Didier Gasparutto, Olga S Fedorova, Alexander A Ishchenko, Hervé Leh, Malcolm Buckle, Barbara Tudek, Murat Saparbaev
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51776 (2012)
BACKGROUND: Oxygen free radicals induce lipid peroxidation (LPO) that damages and breaks polyunsaturated fatty acids in cell membranes. LPO-derived aldehydes and hydroxyalkenals react with DNA leading to the formation of etheno(ε)-bases including 1,
Externí odkaz:
https://doaj.org/article/c92065d10f734f3596ea880672eeab40
Autor:
Claude Nogues, Hervé Leh, Christopher G Langendorf, Ruby H P Law, Ashley M Buckle, Malcolm Buckle
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12152 (2010)
BACKGROUND: Non-specific binding to biosensor surfaces is a major obstacle to quantitative analysis of selective retention of analytes at immobilized target molecules. Although a range of chemical antifouling monolayers has been developed to address
Externí odkaz:
https://doaj.org/article/32a678fe0a2f4f5c9b09c606ac5424d5
Autor:
Olivier Delelis, Vincent Parissi, Hervé Leh, Gladys Mbemba, Caroline Petit, Pierre Sonigo, Eric Deprez, Jean-François Mouscadet
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e608 (2007)
BACKGROUND: HIV-1 integrase (IN) catalyses the retroviral integration process, removing two nucleotides from each long terminal repeat and inserting the processed viral DNA into the target DNA. It is widely assumed that the strand transfer step has n
Externí odkaz:
https://doaj.org/article/22e2c5e08bc8405293a92f5115fcfafc