Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hervé Farine"'
Autor:
Peter Blattmann, Hervé Farine, Brian Dan, Nicole Stiffler, Thomas Lefebvre, Christine Huynh, Patricia N. Sidharta, Jasper Dingemanse, Richard W. D. Welford, Marcel Keller, Daniel S. Strasser
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract CXCL12 acts as a chemoattractant by binding to the receptor CXCR4. The (atypical) chemokine receptor ACKR3 (CXCR7) scavenges CXCL12. Antagonism of ACKR3 thus leads to an increase in CXCL12 concentrations that has been used as a pharmacodynam
Externí odkaz:
https://doaj.org/article/e53b8c21584147f092daf12cfbcb0485
Autor:
Marion Anliker‐Ort, Jasper Dingemanse, Hervé Farine, Peter Groenen, Rüdiger Kornberger, John van den Anker, Priska Kaufmann
Publikováno v:
British Journal of Clinical Pharmacology. 89:380-389
Autor:
Julia Marrie, Enrico Vezzali, Anna Sassi, Nadège Baumlin, Ulrich Mentzel, Marianne M. Martinic, Hervé Farine, Laetitia Pouzol, Mélanie Tunis
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(3)
Current strategies for the treatment of demyelinating diseases such as multiple sclerosis (MS) are based on anti-inflammatory or immunomodulatory drugs. Those drugs have the potential to reduce the frequency of new lesions but do not directly promote
Autor:
Richard W. D. Welford, Agata Sebastian, Alexander Schmidt, Daniel S. Strasser, Marcel P Keller, Lukasz Kozera, Hervé Farine
Publikováno v:
Journal of proteome research. 19(10)
One of the most important advantages of mass spectrometry is the ability to quantify proteins and their modifications in parallel to obtain a holistic picture of the protein of interest. Here, we present a hybrid immunoaffinity targeted mass spectrom
Autor:
Marten Trendelenburg, Andrea Kieninger-Graefitsch, Gabin M Pierlot, Marcel P Keller, Daniel S. Strasser, Estelle Gerossier, Marianne M Martinic, Sylvie Froidevaux, Virginie Sippel, Paulina Kulig, Ursula Grieder, Hervé Farine, Mark Murphy
Publikováno v:
Poster presentations.
Background Reported here is the characterization of cenerimod, a novel, potent, selective, and orally active sphingosine-1-phosphate receptor 1 (S1P1) modulator in the context of SLE. Methods Lymphocytes from patients with SLE and healthy subjects we
Autor:
Daniel S Strasser, Estelle Gerossier, Virginie Sippel, Ursula Grieder, Andrea Kieninger-Graefitsch, Gabin Pierlot, Hervé Farine, Paulina Kulig, Marcel Keller, Sylvie Froidevaux, Marten Trendelenburg, Mark Murphy, Marianne Martinic
Publikováno v:
Oral presentations.
Autor:
Hervé Farine, Nonhlanhla Lunjani, Peter M.A. Groenen, Eugen Bersuch, Juliane Schreiber, Andrew L. Croxford, Ge Tan, Petr Kubena, Mübeccel Akdis, Anita Dreher, Tadech Boonpiyathad, Beate Rückert, Daniel S. Strasser, Pattraporn Satitsuksanoa, Martine Clozel, HW Duchna, Gertruda Capova, Cezmi A. Akdis, David Mirer, Ellen D. Renner
Publikováno v:
Allergy 75, 84-94 (2019)
Background Asthma patients present with distinct immunological profiles, with a predominance of type 2 endotype. The aim of this study was to investigate the impact of high‐altitude treatment on the clinical and immunological response in asthma. Me
Autor:
Dominik Lott, Patricia N. Sidharta, Hervé Farine, Martine Gehin, Milena Issac, Jasper Dingemanse, Daniel S. Strasser
Publikováno v:
Basicclinical pharmacologytoxicology. 124(6)
ACT-774312 is an antagonist of the chemoattractant receptor-homologous molecule expressed on T helper (Th) 2 cells (CRTH2), in development for the treatment of nasal polyposis or other allergic and type-2 inflammatory diseases. Placebo, single doses
Autor:
Hervé Farine, Julie Hoerner, Peter M.A. Groenen, Daniel S. Strasser, Martin Holdener, Patricia N. Sidharta, Martine Gehin, Jasper Dingemanse, René Roscher, Jochen Zisowsky
Publikováno v:
European Journal of Molecular and Clinical Medicine, Vol 2, Iss 4-5, Pp 118-125 (2015)
Biomarkers have shown to improve success rates in the development of novel drugs, providing essential information in the early phases of clinical development for decision-making. Chemoattractant receptor-homologous molecule expressed on Th2 cells (CR