Výsledky vyhledávání - "Hervé Duborjal"

Ultradeep Pyrosequencing of NS3 To Predict Response to Triple Therapy with Protease Inhibitors in Previously Treated Chronic Hepatitis C Patients

Autor: Olivier François, Katia Fusillier, Michael G. B. Blum, Jean-Pierre Zarski, Sylvie Larrat, Pauline Tremeaux, Patrice Morand, Réjane Beugnot, Alice Marlu, Jean-Baptiste Claude, Agnès Plages, Om Kulkarni, Anne Signori-Schmuck, Julien Lupo, Hervé Duborjal, Vincent Leroy

Publikováno v: Journal of Clinical Microbiology
Journal of Clinical Microbiology, American Society for Microbiology, 2015, 53 (2), pp.389-97

Despite the gain in sustained virological responses (SVR) provided by protease inhibitors (PIs), failures still occur. The aim of this study was to determine if a baseline analysis of the NS3 region using ultradeep pyrosequencing (UDPS) can help to p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679a126025eda834e9adccf0712fde0c
https://doi.org/10.1128/jcm.02547-14

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Large Functional Range of Steady-State Levels of Nuclear and Mitochondrial Transcripts Coding for the Subunits of the Human Mitochondrial OXPHOS System

Autor: Bénédicte Mousson de Camaret, Hervé Duborjal, Réjane Beugnot, Jean-Paul Issartel

Publikováno v: Genome Research. 12:1901-1909

We have measured, by reverse transcription and real-time quantitative PCR, the steady-state levels of the mitochondrial and nuclear transcripts encoding several subunits of the human oxidative phosphorylation (OXPHOS) system, in different normal tiss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f8a59c4e9b7f0c4d5d29a738f6f0b5
https://doi.org/10.1101/gr.194102

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Pyruvate reverses metabolic effects produced by hypoxia in glioma and hepatoma cell cultures11A preliminary report has already appeared in abstract form [1]

Autor: Xavier Leverve, Catherine Riva-Lavieille, Christine Bachelet, R. Massarelli, Emilie Roudier, Hervé Duborjal, Anne Perrin

Publikováno v: Biochimie. 84:1003-1011

The intervention of pyruvate in glucose metabolism was investigated during hypoxic stress in tumour cell cultures having respiratory capacities under normoxic conditions. Results obtained with nuclear magnetic resonance (NMR) spectroscopy showed that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc6003ccaa5a8407a98b04edf7f74eb9
https://doi.org/10.1016/s0300-9084(02)00008-1

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Distal genes of thenuooperon ofRhodobacter capsulatusequivalent to the mitochondrial ND subunits are all essential for the biogenesis of the respiratory NADH–ubiquinone oxidoreductase

Autor: Béatrice Pierrard, Alain Dupuis, Mireille Chevallet, Joël Lunardi, Ronald van Belzen, Elisabeth Darrouzet, Simon P. J. Albracht, Hervé Duborjal

Publikováno v: Molecular Microbiology. 28:531-541

Seven out of the 13 proteins encoded by the mitochondrial genome of mammals (peptides ND1 to ND6 plus ND4L) are subunits of the respiratory NADH–ubiquinone oxidoreductase (complex I). The function of these ND subunits is still poorly understood. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70448db93ebc4c47f1a9a0b49d253989
https://doi.org/10.1046/j.1365-2958.1998.00814.x

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Immuno-purification of a dimeric subcomplex of the respiratory NAHD-CoQ reductase ofRhodobacter capsulatusequivalent to the FP fraction of the mitochondrial complex I

Autor: Hervé Duborjal, Alain Dupuis, Jean-Paul Issartel, Agnès Chapel, Silvie Kieffer, Joël Lunardi

Publikováno v: FEBS Letters. 405:345-350

The Rhodobacter capsulatus genes encoding the NUOE and NUOF subunits, equivalent to the 24 kDa and 51 kDa subunits of the mammalian mitochondrial complex I, have been sequenced. According to the nucleotide sequence, the NUOE subunit is 389 amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc8cdce5401feab8b55405c34d20aed
https://doi.org/10.1016/s0014-5793(97)00212-3

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Quantitative Single-letter Sequencing: a method for simultaneously monitoring numerous known allelic variants in single DNA samples

Autor: Stéphane Blanc, Baptiste Monsion, Hervé Duborjal

Publikováno v: BMC Genomics, Vol 9, Iss 1, p 85 (2008)
BMC Genomics
BMC Genomics, BioMed Central, 2008, 9 (85), pp.1-12. ⟨10.1186/1471-2164-9-85⟩
BMC Genomics 85 (9), 1-12. (2008)

Background Pathogens such as fungi, bacteria and especially viruses, are highly variable even within an individual host, intensifying the difficulty of distinguishing and accurately quantifying numerous allelic variants co-existing in a single nuclei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5111aa62e75e9235d3788648a689d1ca
http://www.biomedcentral.com/1471-2164/9/85

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Quantification of Mitochondrial DNA Deletion, Depletion, and Overreplication: Application to Diagnosis

Autor: Béatrice Chabi, Jean Paul Issartel, Hervé Duborjal, Bénédicte Mousson de Camaret, Georges Stepien

Publikováno v: Clinical Chemistry
Clinical Chemistry, 2003, 49 (8), pp.1309-1317. ⟨10.1373/49.8.1309⟩
Clinical Chemistry, American Association for Clinical Chemistry, 2003, 49 (8), pp.1309-1317. ⟨10.1373/49.8.1309⟩
Découverte des Génomes et Expression des Gènes
Découverte des Génomes et Expression des Gènes, May 2003, Paris, France. 1 p., 2003

Background: Many mitochondrial pathologies are quantitative disorders related to tissue-specific deletion, depletion, or overreplication of mitochondrial DNA (mtDNA). We developed an assay for the determination of mtDNA copy number by real-time quant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b334dded6182960c6160f4ede7044f
https://hal.inrae.fr/hal-02940646

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Pyruvate reverses metabolic effects produced by hypoxia in glioma and hepatoma cell cultures

Autor: Anne, Perrin, Emilie, Roudier, Hervé, Duborjal, Christine, Bachelet, Catherine, Riva-Lavieille, Xavier, Leverve, Raphaël, Massarelli

Publikováno v: Biochimie
Biochimie, Elsevier, 2002, 84 (10), pp.1003-11
Biochimie, 2002, 84 (10), pp.1003-11

International audience; The intervention of pyruvate in glucose metabolism was investigated during hypoxic stress in tumour cell cultures having respiratory capacities under normoxic conditions. Results obtained with nuclear magnetic resonance (NMR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1b2a4855ab41e50c60c33179b1013da9
https://www.hal.inserm.fr/inserm-00389953

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Nuclear DNA origin of mitochondrial complex I deficiency in fatal infantile lactic acidosis evidenced by transnuclear complementation of cultured fibroblasts

Autor: Joël Lunardi, René de Coo, Anne Lombès, Hervé Duborjal, Réjane Beugnot, Isabelle Pignot-Paintrand, Vincent Procaccio, Jean-Paul Issartel, Bénédicte Mousson, François Feillet, Guy Putet, Hubert J.M. Smeets

Publikováno v: Journal of Clinical Investigation, 104(1), 83-92. The American Society for Clinical Investigation

We have studied complex I (NADH-ubiquinone reductase) defects of the mitochondrial respiratory chain in 2 infants who died in the neonatal period from 2 different neurological forms of severe neonatal lactic acidosis. Specific and marked decrease in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d24cb8e814ed67186f073e8ada367d
https://pure.eur.nl/en/publications/ca00874d-3c46-4e6f-9952-e9c1eb604c6e

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