Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hervé Besançon"'
Autor:
Hervé Besançon, Viktoriia Babiychuk, Yu Larpin, René Köffel, Dominik Schittny, Lara Brockhus, Lucy J. Hathaway, Parham Sendi, Annette Draeger, Eduard Babiychuk
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of patho
Externí odkaz:
https://doaj.org/article/ef137a52471f4d6bbf852b1b4d4f936b
Publikováno v:
Cells, Vol 11, Iss 1, p 166 (2022)
The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their vir
Externí odkaz:
https://doaj.org/article/1a6c0cf01d9f4eb68bc7fbae3a765c70
Publikováno v:
Toxins, Vol 13, Iss 2, p 126 (2021)
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small
Externí odkaz:
https://doaj.org/article/5850a966b2c24dbba6cd675c17b075bb
Autor:
René Köffel, Heidi Wolfmeier, Yu Larpin, Hervé Besançon, Roman Schoenauer, Viktoria S. Babiychuk, Patrick Drücker, Thomas Pabst, Timothy J. Mitchell, Eduard B. Babiychuk, Annette Draeger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell
Externí odkaz:
https://doaj.org/article/ab204a27906c4eb7b16198098641d220
Autor:
Eduard B. Babiychuk, Yu Larpin, Annette Draeger, Mircea-Ioan Iacovache, Victoriia S. Babiychuk, Hervé Besançon, Benoît Zuber, René Köffel
Publikováno v:
The FASEB Journal. 34:1665-1678
Bacterial infectious diseases can lead to death or to serious illnesses. These outcomes are partly the consequence of pore‐forming toxins, which are secreted by the pathogenic bacteria (eg, pneumolysin of Streptococcus pneumoniae). Pneumolysin bind
Publikováno v:
Toxins
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small
Autor:
Parham Sendi, Dominik Schittny, Viktoriia S. Babiychuk, Yu Larpin, René Köffel, Eduard B. Babiychuk, Annette Draeger, Lara Brockhus, Lucy J. Hathaway, Hervé Besançon
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Nanobiotechnology
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), p. 46. BioMed Central 10.1186/s12951-021-00775-x
Journal of Nanobiotechnology
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), p. 46. BioMed Central 10.1186/s12951-021-00775-x
Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of pathogen clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb5557779461e243883cb8371dabbc
https://doi.org/10.21203/rs.3.rs-52770/v1
https://doi.org/10.21203/rs.3.rs-52770/v1
Autor:
Miloš, Stojanov, Hervé, Besançon, Tiia, Snäkä, Denise, Nardelli-Haefliger, Roy, Curtiss, David, Baud
Publikováno v:
Vaccine. 38(26)
In most attenuated Salmonella enterica vaccines, heterologous antigens are expressed under the control of strong inducible promoters to ensure a high level of synthesis. Although high expression levels of the antigen can improve the immunogenicity of