Chemical Genetic Identification of PKC Epsilon Substrates in Mouse Brain.

Autor: Dugan MP; Department of Neuroscience, The University of Texas at Austin, Austin, Texas, USA., Ferguson LB; Department of Neuroscience, The University of Texas at Austin, Austin, Texas, USA., Hertz NT; Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute at the University of California San Francisco, San Francisco, California, USA; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USA., Chalkley RJ; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USA., Burlingame AL; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USA., Shokat KM; Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute at the University of California San Francisco, San Francisco, California, USA., Parker PJ; The Francis Crick Institute, London, United Kingdom; School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom., Messing RO; Department of Neuroscience, The University of Texas at Austin, Austin, Texas, USA. Electronic address: romessing@austin.utexas.edu.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2023 Apr; Vol. 22 (4), pp. 100522. Date of Electronic Publication: 2023 Feb 28.

Defining the proteolytic landscape during enterovirus infection.

Autor: Saeed M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America.; Department of Biochemistry, Boston University School of Medicine, Boston, MA, United States of America.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, United States of America., Kapell S; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America.; Department of Biochemistry, Boston University School of Medicine, Boston, MA, United States of America.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, United States of America.; The Center for Infectious Medicine, Department of Medicine HS, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden., Hertz NT; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, United States of America.; Department of Biology, Stanford University, Stanford, CA, United States of America., Wu X; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America., Bell K; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America., Ashbrook AW; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America., Mark MT; Proteomics Resource Center, The Rockefeller University, New York, NY, United States of America., Zebroski HA; Proteomics Resource Center, The Rockefeller University, New York, NY, United States of America., Neal ML; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States of America., Flodström-Tullberg M; The Center for Infectious Medicine, Department of Medicine HS, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden., MacDonald MR; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America., Aitchison JD; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States of America.; Departments of Pediatrics and Biochemistry, University of Washington, Seattle, WA, United States of America.; Institute for Systems Biology, Seattle, WA, United States of America., Molina H; Proteomics Resource Center, The Rockefeller University, New York, NY, United States of America., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Sep 30; Vol. 16 (9), pp. e1008927. Date of Electronic Publication: 2020 Sep 30 (Print Publication: 2020).

Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration.

Autor: Hertz NT; Department of Biology, Stanford University, Stanford, CA, USA; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA., Adams EL; Department of Biology, Stanford University, Stanford, CA, USA; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA., Weber RA; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA., Shen RJ; Department of Biology, Stanford University, Stanford, CA, USA., O'Rourke MK; Department of Biology, Stanford University, Stanford, CA, USA., Simon DJ; Department of Biology, Stanford University, Stanford, CA, USA; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA., Zebroski H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Olsen O; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA., Morgan CW; Departments of Pharmaceutical Chemistry and Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., Mileur TR; Department of Biology, Stanford University, Stanford, CA, USA., Hitchcock AM; Department of Biology, Stanford University, Stanford, CA, USA., Sinnott Armstrong NA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Wainberg M; Department of Computer Science, Stanford University School of Engineering, Stanford, CA, USA., Bassik MC; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Molina H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Wells JA; Departments of Pharmaceutical Chemistry and Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., Tessier-Lavigne M; Department of Biology, Stanford University, Stanford, CA, USA; Laboratory of Brain Development and Repair, The Rockefeller University, New York, NY, USA. Electronic address: tessier3@stanford.edu.

Publikováno v: Neuron [Neuron] 2019 Aug 07; Vol. 103 (3), pp. 412-422.e4. Date of Electronic Publication: 2019 Jun 17.

N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation.

Autor: Bowie LE; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada., Maiuri T; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada., Alpaugh M; Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada., Gabriel M; Department of Biochemistry, Western University, London, ON N6A 3K7, Canada., Arbez N; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore MD 21205., Galleguillos D; Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada., Hung CLK; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada., Patel S; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada., Xia J; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada., Hertz NT; Mitokinin, LLC, New York, NY 10006., Ross CA; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore MD 21205., Litchfield DW; Department of Biochemistry, Western University, London, ON N6A 3K7, Canada., Sipione S; Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada., Truant R; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada; truantr@mcmaster.ca.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Jul 24; Vol. 115 (30), pp. E7081-E7090. Date of Electronic Publication: 2018 Jul 09.

Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.

Autor: Orr AL; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA., Rutaganira FU; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA., de Roulet D; Mitokinin LLC, 2 Wall Street, 4th Floor, New York, NY, USA., Huang EJ; Department of Pathology, University of California, San Francisco, San Francisco, CA, USA., Hertz NT; Mitokinin LLC, 2 Wall Street, 4th Floor, New York, NY, USA., Shokat KM; Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA; Mitokinin LLC, 2 Wall Street, 4th Floor, New York, NY, USA., Nakamura K; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA. Electronic address: ken.nakamura@gladstone.ucsf.edu.

Publikováno v: Neurochemistry international [Neurochem Int] 2017 Oct; Vol. 109, pp. 106-116. Date of Electronic Publication: 2017 Apr 20.