Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hershberger PM"'
Autor:
Zoutendam Ph, Switzer Ag, T. P. Demuth, Tracy L. Twinem, Imbus R, Paula M. Koenigs, Paule Sm, Coleman Mc, Kraft Wg, Hershberger Pm, F. J. Rourke, Davis Bw, Devries Ca, Yelm Ke, Richard Siehnel
Publikováno v:
The Journal of antibiotics. 51(9)
This reports the synthesis and in vitro antimicrobial properties of a series of 2-thioether-linked quinolonyl-carbapenems. Although the title compounds exhibited broad spectrum activity, the MICs were generally higher than those observed for selected
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Autor:
Dobrovolskaite A; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Moots H; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Tantak MP; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Shah K; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Thomas J; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Dinara S; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Massaro C; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States., Hershberger PM; Sanford Burnham Medical Research Institute, 6400 Sanger Road, Orlando, Florida 32827, United States., Maloney PR; Sanford Burnham Medical Research Institute, 6400 Sanger Road, Orlando, Florida 32827, United States., Peddibhotla S; Sanford Burnham Medical Research Institute, 6400 Sanger Road, Orlando, Florida 32827, United States., Sugarman E; Sanford Burnham Medical Research Institute, 6400 Sanger Road, Orlando, Florida 32827, United States., Litherland S; Advent Health Cancer Institute, 2520 North Orange Ave, Suite 104, Orlando, Florida 32804, United States., Arnoletti JP; Advent Health Cancer Institute, 2520 North Orange Ave, Suite 104, Orlando, Florida 32804, United States., Jha RK; Laboratory of Pathology, Center for Cancer Research, 10 Center Drive, Building 10, Room 2N106, Bethesda, Maryland 20892-1500, United States., Levens D; Laboratory of Pathology, Center for Cancer Research, 10 Center Drive, Building 10, Room 2N106, Bethesda, Maryland 20892-1500, United States., Phanstiel O 4th; University of Central Florida, Biomolecular Research Annex, 12722 Research Parkway, Orlando, Florida 32826, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2022 Nov 24; Vol. 65 (22), pp. 15391-15415. Date of Electronic Publication: 2022 Nov 16.
Autor:
Sangaralingham SJ; Cardiorenal Research Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905; sangaralingham.jeson@mayo.edu smalany@cop.ufl.edu burnett.john@mayo.edu.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905., Whig K; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Peddibhotla S; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037.; Department of Pharmacodynamics, University of Florida, Gainesville, FL 32610., Kirby RJ; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Sessions HE; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Maloney PR; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Hershberger PM; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Mose-Yates H; Department of Pharmacodynamics, University of Florida, Gainesville, FL 32610., Hood BL; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Vasile S; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037., Pan S; Cardiorenal Research Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905., Zheng Y; Cardiorenal Research Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905., Malany S; Chemical Genomics Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037; sangaralingham.jeson@mayo.edu smalany@cop.ufl.edu burnett.john@mayo.edu.; Department of Pharmacodynamics, University of Florida, Gainesville, FL 32610., Burnett JC Jr; Cardiorenal Research Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905; sangaralingham.jeson@mayo.edu smalany@cop.ufl.edu burnett.john@mayo.edu.; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Dec 28; Vol. 118 (52).
Autor:
Esquejo RM; Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA., Roqueta-Rivera M; Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA., Shao W; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Phelan PE; Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA., Seneviratne U; Chemical Biology and Medicine Design, Pfizer Inc, Cambridge, MA 02139, USA., Am Ende CW; Pfizer Worldwide Research & Development, Eastern Point Road, Groton, CT 06340, USA., Hershberger PM; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Machamer CE; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Espenshade PJ; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Osborne TF; Sanford Burnham Prebys Medical Discovery Institute, Orlando, FL 32827, USA. Electronic address: tosborn9@jhmi.edu.
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2021 Feb 18; Vol. 28 (2), pp. 169-179.e7. Date of Electronic Publication: 2020 Oct 22.
Autor:
Peddibhotla S; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: peddibhotlas@seminolestate.edu., Hershberger PM; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Jason Kirby R; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Sugarman E; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Maloney PR; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Hampton Sessions E; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Divlianska D; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Morfa CJ; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Terry D; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Pinkerton AB; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Smith LH; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Malany S; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; College of Pharmacy, University of Florida, 1345 Center Drive, Gainesville, FL 32610, USA. Electronic address: smalany@cop.ufl.edu.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Feb 15; Vol. 30 (4), pp. 126899. Date of Electronic Publication: 2019 Dec 17.