Mitochondrial ROS production by neutrophils is required for host antimicrobial function against Streptococcus pneumoniae and is controlled by A2B adenosine receptor signaling.

Autor: Herring, Sydney E.¹ (AUTHOR), Mao, Sovathiro¹ (AUTHOR), Bhalla, Manmeet¹ (AUTHOR), Tchalla, Essi Y. I.¹ (AUTHOR), Kramer, Jill M.² (AUTHOR), Bou Ghanem, Elsa N.¹ (AUTHOR) Elsaboug@buffalo.edu

Publikováno v: PLoS Pathogens. 11/14/2022, Vol. 18 Issue 11, p1-29. 29p.

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Extracellular adenosine signaling reverses the age‐driven decline in the ability of neutrophils to kill Streptococcus pneumoniae.

Autor: Bhalla, Manmeet, Simmons, Shaunna R., Abamonte, Alexsandra, Herring, Sydney E., Roggensack, Sara E., Bou Ghanem, Elsa N.

Publikováno v: Aging Cell; Oct2020, Vol. 19 Issue 10, p1-12, 12p

Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection.

Autor: Simmons SR; Department of Microbiology and Immunology, School of Medicine, University at Buffalo, Buffalo, NY, USA., Herring SE; Department of Microbiology and Immunology, School of Medicine, University at Buffalo, Buffalo, NY, USA., Tchalla EYI; Department of Microbiology and Immunology, School of Medicine, University at Buffalo, Buffalo, NY, USA., Lenhard AP; Department of Microbiology and Immunology, School of Medicine, University at Buffalo, Buffalo, NY, USA., Bhalla M; Department of Microbiology and Immunology, School of Medicine, University at Buffalo, Buffalo, NY, USA., Bou Ghanem EN; Department of Microbiology and Immunology, School of Medicine, University at Buffalo, Buffalo, NY, USA. Elsaboug@buffalo.edu.

Publikováno v: Immunity & ageing : I & A [Immun Ageing] 2024 Jun 05; Vol. 21 (1), pp. 34. Date of Electronic Publication: 2024 Jun 05.