Glycosphingolipids and the central regulation of metabolism: Sugar analogues as research tools

Autor: Herrera Moro Chao, D.

This thesis describes different studies using sugar analogues to investigate the impact of glycosphingolipid metabolism, in different brain structures involved in the development of α-synucleinopathies and the control of energy homeostasis. Part I c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2dd2d5f07730b54f3078049acc141f5c
https://dare.uva.nl/personal/pure/en/publications/glycosphingolipids-and-the-central-regulation-of-metabolism(aac27c46-52bb-47da-a179-04de1049806f).html

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The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.

Autor: Herrera Moro Chao D; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Laboratory of Endocrinology, Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Wang Y; Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Foppen E; Laboratory of Endocrinology, Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Ottenhoff R; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., van Roomen C; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Parlevliet ET; Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., van Eijk M; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden, the Netherlands., Verhoek M; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden, the Netherlands., Boot R; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden, the Netherlands., Marques AR; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden, the Netherlands., Scheij S; Department of Medical Biochemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Mirzaian M; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden, the Netherlands., Kooijman S; Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Jansen K; Laboratory of Endocrinology, Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands., Wang D; Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands.; Institute of Plant Protection, Chinese Academy of Agricultural Science, Beijing, China., Mergen C; Helmholtz Diabetes Center and German Center for Diabetes Research, Helmholtz Zentrum München, Neuherberg, Germany, and Division of Metabolic Diseases, Technische Universität München, Munich, Germany., Seeley RJ; Department of Surgery, University of Michigan, MI., Tschöp MH; Helmholtz Diabetes Center and German Center for Diabetes Research, Helmholtz Zentrum München, Neuherberg, Germany, and Division of Metabolic Diseases, Technische Universität München, Munich, Germany., Overkleeft H; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden, the Netherlands., Rensen PCN; Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands., Kalsbeek A; Laboratory of Endocrinology, Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.; Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands., Aerts JMFG; Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden, the Netherlands j.m.f.g.aerts@lic.leidenuniv.nl., Yi CX; Laboratory of Endocrinology, Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

Publikováno v: Diabetes [Diabetes] 2019 Dec; Vol. 68 (12), pp. 2223-2234. Date of Electronic Publication: 2019 Oct 02.

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes.

Autor: Kallemeijn WW; Department of Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Scheij S; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Hoogendoorn S; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands., Witte MD; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands., Herrera Moro Chao D; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., van Roomen CP; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Ottenhoff R; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Overkleeft HS; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands., Boot RG; Department of Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Aerts JM; Department of Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: PloS one [PLoS One] 2017 Feb 16; Vol. 12 (2), pp. e0170268. Date of Electronic Publication: 2017 Feb 16 (Print Publication: 2017).