Signs of early cellular dysfunction in multiple system atrophy.

Autor: Herrera‐Vaquero, M.¹ (AUTHOR), Heras‐Garvin, A.¹ (AUTHOR), Krismer, F.¹ (AUTHOR), Deleanu, R.² (AUTHOR), Boesch, S.¹ (AUTHOR), Wenning, G. K.¹ (AUTHOR), Stefanova, N.¹ (AUTHOR) Nadia.Stefanova@i-med.ac.at

Publikováno v: Neuropathology & Applied Neurobiology. Feb2021, Vol. 47 Issue 2, p268-282. 15p.

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The molecular tweezer CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy.

Autor: Herrera-Vaquero M; Division of Neurobiology, Department of Neurology, Medical University of Innsbruck, Austria., Bouquio D; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Kallab M; Division of Neurobiology, Department of Neurology, Medical University of Innsbruck, Austria., Biggs K; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Nair G; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Ochoa J; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Brain Research Institute and Molecular Biology Institute, University of California, Los Angeles, CA, USA., Heras-Garvin A; Division of Neurobiology, Department of Neurology, Medical University of Innsbruck, Austria., Heid C; Institute of Chemistry, University of Duisburg-Essen, Essen, Germany., Hadrovic I; Institute of Chemistry, University of Duisburg-Essen, Essen, Germany., Poewe W; Division of Neurobiology, Department of Neurology, Medical University of Innsbruck, Austria., Wenning GK; Division of Neurobiology, Department of Neurology, Medical University of Innsbruck, Austria., Klärner FG; Institute of Chemistry, University of Duisburg-Essen, Essen, Germany., Schrader T; Institute of Chemistry, University of Duisburg-Essen, Essen, Germany., Bitan G; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Brain Research Institute and Molecular Biology Institute, University of California, Los Angeles, CA, USA. Electronic address: gbitan@mednet.ucla.edu., Stefanova N; Division of Neurobiology, Department of Neurology, Medical University of Innsbruck, Austria. Electronic address: nadia.stefanova@i-med.ac.at.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2019 Nov 01; Vol. 1865 (11), pp. 165513. Date of Electronic Publication: 2019 Jul 16.

Region-Specific Effects of Immunotherapy With Antibodies Targeting α-synuclein in a Transgenic Model of Synucleinopathy.

Autor: Kallab M; Division of Neurobiology, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria., Herrera-Vaquero M; Division of Neurobiology, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria., Johannesson M; BioArctic AB, Stockholm, Sweden., Eriksson F; BioArctic AB, Stockholm, Sweden., Sigvardson J; BioArctic AB, Stockholm, Sweden., Poewe W; Division of Neurobiology, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria., Wenning GK; Division of Neurobiology, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria., Nordström E; BioArctic AB, Stockholm, Sweden., Stefanova N; Division of Neurobiology, Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2018 Jul 04; Vol. 12, pp. 452. Date of Electronic Publication: 2018 Jul 04 (Print Publication: 2018).

Inhibition of Protein Aggregation and Endoplasmic Reticulum Stress as a Targeted Therapy for α-Synucleinopathy.

Autor: Siwecka, Natalia¹ (AUTHOR) natalia.siwecka@stud.umed.lodz.pl, Saramowicz, Kamil¹ (AUTHOR), Galita, Grzegorz¹ (AUTHOR), Rozpędek-Kamińska, Wioletta¹ (AUTHOR), Majsterek, Ireneusz¹ (AUTHOR) ireneusz.majsterek@umed.lodz.pl

Publikováno v: Pharmaceutics. Aug2023, Vol. 15 Issue 8, p2051. 45p.