Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hernando Diaz-Arauzo"'
Publikováno v:
Health Physics. 96:477-482
Emanation of radon ( 222 Rn) from granite used for countertops and mantels was measured with continuous and integrating radon monitors. Each of the 24 granite samples emitted a measurable amount of radon. Of the two analytical methods that utilized e
Autor:
Huang Qi, Chunrong Ma, Brad Harris, Mundla S. Reddy, Phil Skolnick, Hernando Diaz-Arauzo, James M. Cook, Ruth McKernan, Eric Cox
Publikováno v:
Journal of Medicinal Chemistry. 41:2537-2552
A pharmacophore and an alignment rule have previously been reported for BzR agonist ligands. The design and synthesis of 6-(propyloxy)-4-(methoxymethyl)-β-carboline-3-carboxylic acid ethyl ester (6-PBC, 24, IC50 = 8.1 nM) was based on this pharmacop
Publikováno v:
Life Sciences. 49:207-216
In order to employ rational drug design in the discovery of selective benzodiazepine receptor agonists and inverse agonists, pharmacophore/receptor models for both these activities must first be established. Recently, a pharmacophore for the inverse
Publikováno v:
Journal of Natural Products. 53:112-124
The first synthesis of 10,11-dihydroxydihydroquinidine N-oxide [7b], a recently isolated metabolite of quinidine, was accomplished in three steps from 1b. The related congener 7a in the quinine series was also prepared, as well as two other analogues
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
In many cases of drug-induced immunologic thrombocytopenia (DITP), a metabolite, rather than the native drug, is suspected of provoking the destructive drug-dependent antibodies (DDAB) responsible for this severe hemorrhagic disorder. However, this h