Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

Autor: Reid, SE, Kay, EJ, Neilson, LJ, Henze, AT, Serneels, J, McGhee, EJ, Dhayade, S, Nixon, C, Mackey, JB, Santi, A, Swaminathan, Karthic, Athineos, D, Papalazarou, V, Patella, F, Roman-Fernandez, A, ElMaghloob, Y, Hernandez-Fernaud, JR, Adams, RH, Ismail, S, Bryant, DM, Salmeron-Sanchez, M, Machesky, LM, Carlin, LM, Blyth, K, Mazzone, M, Zanivan, S

Yes
Tumor progression alters the composition and physical properties of the extracellular matrix. Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis. While endothelial cells are key players in cancer pro

Externí odkaz: http://hdl.handle.net/10454/17727

Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.

Autor: Kay EJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Paterson K; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK., Riera-Domingo C; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Däbritz JHM; Cancer Research UK Beatson Institute, Glasgow, UK., Tardito S; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Boldrini C; Cancer Research UK Beatson Institute, Glasgow, UK., Hernandez-Fernaud JR; Cancer Research UK Beatson Institute, Glasgow, UK., Athineos D; Cancer Research UK Beatson Institute, Glasgow, UK., Dhayade S; Cancer Research UK Beatson Institute, Glasgow, UK., Stepanova E; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany., Gjerga E; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany., Neilson LJ; Cancer Research UK Beatson Institute, Glasgow, UK., Lilla S; Cancer Research UK Beatson Institute, Glasgow, UK., Hedley A; Cancer Research UK Beatson Institute, Glasgow, UK., Koulouras G; Cancer Research UK Beatson Institute, Glasgow, UK., McGregor G; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Jamieson C; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow, UK., Johnson RM; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada., Park M; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.; Department of Medicine, McGill University, Montreal, Quebec, Canada.; Department of Oncology, McGill University, Montreal, Quebec, Canada., Kirschner K; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Miller C; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Kamphorst JJ; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Loayza-Puch F; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany., Saez-Rodriguez J; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany., Mazzone M; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Blyth K; Cancer Research UK Beatson Institute, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK., Zagnoni M; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK., Zanivan S; Cancer Research UK Beatson Institute, Glasgow, UK. s.zanivan@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. s.zanivan@beatson.gla.ac.uk.

Publikováno v: Nature metabolism [Nat Metab] 2022 Aug; Vol. 4 (8), pp. 1084.

Identification of an RNA sponge that controls the RoxS riboregulator of central metabolism in Bacillus subtilis.

Autor: Durand S; UMR8261, CNRS, Université de Paris, Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France., Callan-Sidat A; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK., McKeown J; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK., Li S; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK., Kostova G; UMR8261, CNRS, Université de Paris, Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France., Hernandez-Fernaud JR; School of Life Sciences, Proteomics Research Technology Platform, University of Warwick, Gibbet Hill Road, Coventry, UK., Alam MT; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK., Millard A; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK., Allouche D; UMR8261, CNRS, Université de Paris, Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France., Constantinidou C; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK., Condon C; UMR8261, CNRS, Université de Paris, Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, 75005 Paris, France., Denham EL; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, UK.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2021 Jun 21; Vol. 49 (11), pp. 6399-6419.

Beyond oil degradation: enzymatic potential of Alcanivorax to degrade natural and synthetic polyesters.

Autor: Zadjelovic V; School of Life Sciences, University of Warwick, Warwick, UK., Chhun A; School of Life Sciences, University of Warwick, Warwick, UK., Quareshy M; School of Life Sciences, University of Warwick, Warwick, UK., Silvano E; School of Life Sciences, University of Warwick, Warwick, UK., Hernandez-Fernaud JR; School of Life Sciences, University of Warwick, Warwick, UK.; Unidad de investigación-HUC, La Laguna-Tenerife, Spain., Aguilo-Ferretjans MM; School of Life Sciences, University of Warwick, Warwick, UK.; Department of Biology, University of the Balearic Islands, Spain., Bosch R; Department of Biology, University of the Balearic Islands, Spain.; IMEDEA (CSIC-UIB), Esporles, Spain., Dorador C; Laboratorio de Complejidad Microbiana y Ecología Funcional, Universidad de Antofagasta, Antofagasta, Chile.; Departamento de Biotecnología, Universidad de Antofagasta, Antofagasta, Chile.; Centre for Biotechnology & Bioengineering (CeBiB), Santiago, Chile., Gibson MI; Department of Chemistry, University of Warwick, Warwick, UK.; Warwick Medical School, University of Warwick, Warwick, UK., Christie-Oleza JA; School of Life Sciences, University of Warwick, Warwick, UK.; Department of Biology, University of the Balearic Islands, Spain.; IMEDEA (CSIC-UIB), Esporles, Spain.

Publikováno v: Environmental microbiology [Environ Microbiol] 2020 Apr; Vol. 22 (4), pp. 1356-1369. Date of Electronic Publication: 2020 Feb 27.

Updates of the In-Gel Digestion Method for Protein Analysis by Mass Spectrometry.

Autor: Goodman JK; School of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, CV 4 7AL, UK., Zampronio CG; Proteomics Research Technology Platform, University of Warwick, Gibbet Hill Road, Coventry, CV 4 7AL, UK., Jones AME; School of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, CV 4 7AL, UK.; Proteomics Research Technology Platform, University of Warwick, Gibbet Hill Road, Coventry, CV 4 7AL, UK., Hernandez-Fernaud JR; Proteomics Research Technology Platform, University of Warwick, Gibbet Hill Road, Coventry, CV 4 7AL, UK.

Publikováno v: Proteomics [Proteomics] 2018 Dec; Vol. 18 (23), pp. e1800236. Date of Electronic Publication: 2018 Nov 25.