Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Hernandez Borrero"'
Publikováno v:
In BBA - Reviews on Cancer August 2021 1876(1)
Autor:
Alexander G. Raufi, Nicholas R. Liguori, Lindsey Carlsen, Cassandra Parker, Liz Hernandez Borrero, Shengliang Zhang, Xiaobing Tian, Anna Louie, Lanlan Zhou, Attila A. Seyhan, Wafik S. El-Deiry
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by early metastasis, late detection, and poor prognosis. Progress towards effective therapy has been slow despite significant efforts. Novel treatment approaches are despe
Externí odkaz:
https://doaj.org/article/9e013afab8844e3382a6ba0292407a29
Autor:
Xiaobing Tian, Shengliang Zhang, Lanlan Zhou, Attila A. Seyhan, Liz Hernandez Borrero, Yiqun Zhang, Wafik S. El-Deiry
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The integrated stress response (ISR) is an evolutionarily conserved intra-cellular signaling network which is activated in response to intrinsic and extrinsic stresses. Various stresses are sensed by four specialized kinases, PKR-like ER kinase (PERK
Externí odkaz:
https://doaj.org/article/5e087687999b4cd98624127086ec17cb
Autor:
Liz Hernandez Borrero, David T Dicker, John Santiago, Jennifer Sanders, Xiaobing Tian, Nagib Ahsan, Avital Lev, Lanlan Zhou, Wafik S El-Deiry
Publikováno v:
eLife, Vol 10 (2021)
Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes, including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with mutant-p53 but we find that unlike
Externí odkaz:
https://doaj.org/article/9c1569a9e1944110b2016496e39309bd
Autor:
Shengliang Zhang, Lindsey Carlsen, Liz Hernandez Borrero, Attila A. Seyhan, Xiaobing Tian, Wafik S. El-Deiry
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 548 (2022)
TP53 is a tumor suppressor gene that encodes a sequence-specific DNA-binding transcription factor activated by stressful stimuli; it upregulates target genes involved in growth suppression, cell death, DNA repair, metabolism, among others. TP53 is th
Externí odkaz:
https://doaj.org/article/82791e06ae89482f9f11405588df6eee
Autor:
Lindsey Carlsen, Kelsey E. Huntington, Lanlan Zhou, Christoph Schorl, Liz J. Hernandez-Borrero, Aakash Jhaveri, Wafik S. El-Deiry, Shengliang Zhang
Publikováno v:
Oncotarget
Colorectal cancer (CRC) caused over 900,000 deaths worldwide in 2020. A majority of late-stage CRC patients are treated with 5-fluorouracil (5-FU) combined with either irinotecan (CPT-11), oxaliplatin, or both. Despite their widespread use, the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c8e77b77c200ae86260458ee21bcf1
https://doi.org/10.18632/oncotarget.28075
https://doi.org/10.18632/oncotarget.28075
Autor:
Jillian R. Strandberg, Anna Louie, Marina Hahn, Praveen Srinivasan, Andrew George, Arielle De La Cruz, Leiqing Zhang, Liz Hernandez Borrero, Kelsey Huntington, Christopher Azzoli, Abbas E. Abbas, Lanlan Zhou, Seulki Lee, Wafik S. El-Deiry
Publikováno v:
Cancer Research. 83:4457-4457
Thoracic therapeutic ionizing radiation is limited by toxicities such as pneumonitis and fibrosis of the lungs. Such limitation restricts therapeutic doses and adversely affects patient quality of life while undergoing and following treatment. ONC201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72c60711243deffa8a6c1de99e664294
https://doi.org/10.1158/1538-7445.am2023-4457
https://doi.org/10.1158/1538-7445.am2023-4457
Akademický článek
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Autor:
Xiaobing Tian, John Santiago, Nagib Ahsan, Wafik S. El-Deiry, Lanlan Zhou, Jennifer A. Sanders, Liz J. Hernandez Borrero, Avital Lev, David T. Dicker
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes, including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with mutant-p53 but we find that unlike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c0fcefbdd3d22e54e582c0e5e1ab00
https://doi.org/10.7554/elife.70429
https://doi.org/10.7554/elife.70429
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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