Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Hernán González-King"'
Autor:
Alena Ivanova, Franziska Kohl, Hernán González-King Garibotti, Renata Chalupska, Aleksander Cvjetkovic, Mike Firth, Karin Jennbacken, Sofia Martinsson, Andreia M. Silva, Ida Viken, Qing-Dong Wang, John Wiseman, Niek Dekker
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Heart failure remains a leading cause of mortality. Therapeutic intervention for heart failure would benefit from targeted delivery to the damaged heart tissue. Here, we applied in vivo peptide phage display coupled with high-throughput Next
Externí odkaz:
https://doaj.org/article/9f8a56535f58403fa172c838efb781c1
Autor:
Hernán González‐King, Patricia G. Rodrigues, Tamsin Albery, Benyapa Tangruksa, Ramya Gurrapu, Andreia M. Silva, Gentian Musa, Dominika Kardasz, Kai Liu, Bengt Kull, Karin Åvall, Katarina Rydén‐Markinhuhta, Tania Incitti, Nitin Sharma, Cecilia Graneli, Hadi Valadi, Kasparas Petkevicius, Miguel Carracedo, Sandra Tejedor, Alena Ivanova, Sepideh Heydarkhan‐Hagvall, Phillipe Menasché, Jane Synnergren, Niek Dekker, Qing‐Dong Wang, Karin Jennbacken
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Small extracellular vesicles (sEV) derived from various cell sources have been demonstrated to enhance cardiac function in preclinical models of myocardial infarction (MI). The aim of this study was to compare different sources of sEV for ca
Externí odkaz:
https://doaj.org/article/c768354e5bb04d27b8a38ee892355c5b
Autor:
Kasparas Petkevicius, Henrik Palmgren, Matthew S. Glover, Andrea Ahnmark, Anne-Christine Andréasson, Katja Madeyski-Bengtson, Hiroki Kawana, Erik L. Allman, Delaney Kaper, Martin Uhrbom, Liselotte Andersson, Leif Aasehaug, Johan Forsström, Simonetta Wallin, Ingela Ahlstedt, Renata Leke, Daniel Karlsson, Hernán González-King, Lars Löfgren, Ralf Nilsson, Giovanni Pellegrini, Nozomu Kono, Junken Aoki, Sonja Hess, Grzegorz Sienski, Marc Pilon, Mohammad Bohlooly-Y, Marcello Maresca, Xiao-Rong Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The regulation of cellular phosphatidylethanolamine (PE) acyl chain composition is poorly understood. Here, the authors show that TLCD1 and TLCD2 proteins mediate the formation of monounsaturated fatty acid-containing PE species and promote the progr
Externí odkaz:
https://doaj.org/article/15464563b39b4d54986a8c040d9d92b8
Autor:
Miguel Carracedo, Elke Ericson, Rasmus Ågren, Anna Forslöw, Katja Madeyski-Bengtson, Anna Svensson, Rebecca Riddle, Jonas Christoffersson, Hernán González-King Garibotti, Bojana Lazovic, Ryan Hicks, Lisa Buvall, Alessia Fornoni, Peter J. Greasley, Mark Lal
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106830- (2023)
Summary: Apolipoprotein L1 (APOL1) high-risk genotypes are associated with increased risk of chronic kidney disease (CKD) in people of West African ancestry. Given the importance of endothelial cells (ECs) in CKD, we hypothesized that APOL1 high-risk
Externí odkaz:
https://doaj.org/article/e7b72c9152f540b5a5332bc61f411e47
Autor:
Muhammad Nawaz, Sepideh Heydarkhan‐Hagvall, Benyapa Tangruksa, Hernán González‐King Garibotti, Yujia Jing, Marco Maugeri, Franziska Kohl, Leif Hultin, Azadeh Reyahi, Alessandro Camponeschi, Bengt Kull, Jonas Christoffersson, Ola Grimsholm, Karin Jennbacken, Martina Sundqvist, John Wiseman, Abdel Wahad Bidar, Lennart Lindfors, Jane Synnergren, Hadi Valadi
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A mRNA, to ischemic tissues for producing new blood vessels is an
Externí odkaz:
https://doaj.org/article/cd41eb4a09a4418b8e2864914218e324
Autor:
Sandra Tejedor, Marc Buigues, Hernán González-King, Andreia M. Silva, Nahuel Aquiles García, Niek Dekker, Pilar Sepúlveda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6467 (2023)
Myocardial fibrosis is a pathological hallmark of cardiac dysfunction. Oncostatin M (OSM) is a pleiotropic cytokine that can promote fibrosis in different organs after sustained exposure. However, OSM released by macrophages during cardiac fibrosis s
Externí odkaz:
https://doaj.org/article/50c689bfd584474f820e1b0637e331aa
Autor:
Rafael Sánchez-Sánchez, Marta Gómez-Ferrer, Ignacio Reinal, Marc Buigues, Estela Villanueva-Bádenas, Imelda Ontoria-Oviedo, Amparo Hernándiz, Hernán González-King, Esteban Peiró-Molina, Akaitz Dorronsoro, Pilar Sepúlveda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) are an emerging alternative to cell-based therapies to treat many diseases. However, the complexity of producing homogeneous populations of EVs in sufficient amount hampers th
Externí odkaz:
https://doaj.org/article/bb045a1c253b487baf6f5e5842645e73
Autor:
Imelda Ontoria-Oviedo, Akaitz Dorronsoro, Rafael Sánchez, Maria Ciria, Marta Gómez-Ferrer, Marc Buigues, Elena Grueso, Sandra Tejedor, Francisco García-García, Hernán González-King, Nahuel A. Garcia, Esteban Peiró-Molina, Pilar Sepúlveda
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Extracellular vesicles (EVs) are small membrane vesicles secreted by most cell types with important roles in cell-to-cell communication. To assess their relevance in the context of heart ischemia, EVs isolated from the AC10 ventricular cardiomyocyte
Externí odkaz:
https://doaj.org/article/0d9f90192df64b1eb5e2de5c3b90829e
Autor:
Hernán González-King, Nahuel García, María Ciria, Sandra Gascón, Rafael Sánchez, Helena Grueso, Marta Gómez, Rubén Martín-Cabezuelo, Vanesa Cava, Pilar Sepúlveda
Publikováno v:
Bio-Protocol, Vol 8, Iss 2 (2018)
During the course of evolution, prokaryote and eukaryote cells have developed elegant and to some extent analogous strategies to communicate with each other and to adapt to their surrounding environment. Eukaryotic cells communicate with each other t
Externí odkaz:
https://doaj.org/article/ed8f6e393a24490285e7fb5b875e6fe4
Autor:
Nahuel A Garcia, Imelda Ontoria-Oviedo, Hernán González-King, Antonio Diez-Juan, Pilar Sepúlveda
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138849 (2015)
Cardiomyocytes (CMs) and endothelial cells (ECs) have an intimate anatomical relationship that is essential for maintaining normal development and function in the heart. Little is known about the mechanisms that regulate cardiac and endothelial cross
Externí odkaz:
https://doaj.org/article/4204e310f2d4434fae1a89cc21b60e32